Detailed information NTG1155478

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: QNH65_RS07405
• Genome accession: NZ_OX352940
• Coordinates: 1513826..1514725 (-)
• Length: 299 a.a.
• NCBI ID: WP_074390054.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 861160_LM_A
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1512262..1513092	1513826..1514725	flank	734

Gene organization within MGE regions

Location: 1512262..1514725

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QNH65_RS07400	-	1512262..1513200 (+)	939	Protein_1435	IS4 family transposase	-
QNH65_RS07405	comR	1513826..1514725 (-)	900	WP_074390054.1	helix-turn-helix domain-containing protein	Regulator

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35382.26 Da
• Isoelectric Point: 4.6029

>NTDB_id=1155478 QNH65_RS07405 WP_074390054.1 1513826..1514725(-) (comR) [Streptococcus suis isolate 861160_LM_A]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKNYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide

• Length: 900 bp

>NTDB_id=1155478 QNH65_RS07405 WP_074390054.1 1513826..1514725(-) (comR) [Streptococcus suis isolate 861160_LM_A]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGAATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_31) (5-60)

• ComR tetratricopeptide (ComR_TPR) (73-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	99.666	100	0.997
comR	Streptococcus suis 05ZYH33	99.666	100	0.997
comR	Streptococcus suis D9	62.126	100	0.625
comR	Streptococcus mutans UA159	43.813	100	0.438
comR	Streptococcus pyogenes MGAS315	37.374	99.331	0.371