Detailed information NTG1155455

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: QNH65_RS03525
• Genome accession: NZ_OX352940
• Coordinates: 727925..730162 (-)
• Length: 745 a.a.
• NCBI ID: WP_024405508.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 861160_LM_A
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 722925..735162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QNH65_RS03495	tmk	723030..723668 (-)	639	WP_024379691.1	dTMP kinase	-
QNH65_RS03500	-	723843..724709 (+)	867	WP_002935357.1	YitT family protein	-
QNH65_RS03505	-	724746..726017 (-)	1272	WP_024405507.1	toxic anion resistance protein	-
QNH65_RS03510	-	726023..726850 (-)	828	WP_011922194.1	hypothetical protein	-
QNH65_RS03515	-	726944..727600 (-)	657	WP_011922763.1	CBS domain-containing protein	-
QNH65_RS03520	-	727783..727908 (-)	126	Protein_686	IS982 family transposase	-
QNH65_RS03525	comEC/celB	727925..730162 (-)	2238	WP_024405508.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
QNH65_RS03530	comEA/celA/cilE	730146..730808 (-)	663	WP_024405509.1	helix-hairpin-helix domain-containing protein	Machinery gene
QNH65_RS03535	-	730875..731621 (-)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
QNH65_RS03540	-	731767..733212 (+)	1446	WP_024405510.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
QNH65_RS03545	-	733364..734149 (+)	786	WP_011922762.1	ABC transporter ATP-binding protein	-
QNH65_RS03550	-	734162..735091 (+)	930	WP_012775038.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84006.03 Da
• Isoelectric Point: 7.8195

>NTDB_id=1155455 QNH65_RS03525 WP_024405508.1 727925..730162(-) (comEC/celB) [Streptococcus suis isolate 861160_LM_A]
MSRLSKLPCQPVHLAVLAVAAYFAVHSFSLLTMCLLSLVLAVFGVRQGKTVFLKTLPLLTLCGLFFGCQKVQWERAAQSA
PEQVTTVQVIPDTIDINGDSLSFRGRADGQNYQVFYKLTSQEEQTYFQNLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNVFDWLSTWRRQALVYVKINFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKETVDKLQIPFSLVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFICLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVKMTWVNGFFIFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRRKKWLLGLSLVLALLFFITK
HPLENEVTVLDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPEFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDSRNIQ
VYRTDQQGAIRFRGWKEWKIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=1155455 QNH65_RS03525 WP_024405508.1 727925..730162(-) (comEC/celB) [Streptococcus suis isolate 861160_LM_A]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCGTTCACCTGGCAGTCTTGGCGGTGGCAGCTTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATGTGCCTGCTCAGCTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGACAGTTTTCCTCA
AAACGCTGCCGCTTCTAACCCTGTGTGGTCTCTTTTTCGGATGCCAAAAGGTCCAATGGGAGCGGGCAGCTCAGTCAGCC
CCAGAGCAAGTGACGACTGTGCAGGTCATTCCAGATACCATAGACATCAATGGCGACAGCTTGTCTTTTCGTGGTCGGGC
TGATGGACAAAACTATCAGGTTTTCTACAAATTAACCAGTCAGGAGGAGCAGACCTATTTTCAAAATCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACTGTCAAGCTAACGGCGATTAAGAAGATTGTCCCTGTCCAGTCTTGGAATGTTTTTGA
CTGGCTGTCAACTTGGCGGAGGCAGGCCTTGGTCTATGTCAAAATCAATTTTCCGGCTCCCATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTTGACCAGATGAGTGACCTCTATTCCAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTGGGCTTTTTCATCGACAAGTTTCGTTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAAC
AGTGGATAAGTTACAAATTCCCTTTTCCCTTGTCTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACGGTCTTTATCTGTCTGTTGATACTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACTTATGCTTTCTTGCTGACGGTCTTTGATTTTGAGGATTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCACTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTCTATCTATCCTCTTGACCTTTGTCTTTTCCTTTGTCTTTGATGTCCTACTCTTGCCAGGTTTGTCAGTC
ATTTTTCTCCTGTCGCCAGTTGTCAAGATGACTTGGGTCAACGGATTTTTCATCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTCTTCT
TGCTCTACGATTTCCACAGGAGAAAGAAATGGCTTCTAGGACTGAGCTTGGTCCTCGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAATGAGGTGACGGTGCTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTAGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTGGATAGGATTGATAGTTTAGTCCTGACCCACACCGACACAGAC
CATGTGGGGGATGTGCTGGAAGTGGCGAAGCAGGTCCAGATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGAATTTGTAGCGACCTTGAAAAAAATCAATGTTCCTGTCCATGTGGTAAAAGTGGGCGACCGCCTACCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCATGGCTCCAAAGGCTCTTCTTATCCTGAATTTTTAGACCATATCGGTGCCAAGATTGCCT
TGGTATCTGCTGGAGAAAACAACCGCTACAAGCATCCTCACCAAGAAACCTTGGAACGATTTGACAGCCGGAATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATTCGCTTCCGAGGTTGGAAGGAGTGGAAGATTGAGACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (215-461)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.774	99.597	0.536
comEC/celB	Streptococcus mitis NCTC 12261	52.646	98.926	0.521
comEC/celB	Streptococcus pneumoniae TIGR4	51.973	98.658	0.513
comEC/celB	Streptococcus pneumoniae Rx1	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae D39	51.701	98.658	0.51
comEC/celB	Streptococcus pneumoniae R6	51.701	98.658	0.51
comEC	Lactococcus lactis subsp. cremoris KW2	49.468	100	0.499