Detailed information NTG1155333

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: QNH74_RS00335
• Genome accession: NZ_OX352806
• Coordinates: 55403..56302 (+)
• Length: 299 a.a.
• NCBI ID: WP_074390054.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 861160_dxerD_hsdSA
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	57036..57866	55403..56302	flank	734

Gene organization within MGE regions

Location: 55403..57866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QNH74_RS00335	comR	55403..56302 (+)	900	WP_074390054.1	helix-turn-helix domain-containing protein	Regulator
QNH74_RS00340	-	56928..57866 (-)	939	Protein_47	IS4 family transposase	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35382.26 Da
• Isoelectric Point: 4.6029

>NTDB_id=1155333 QNH74_RS00335 WP_074390054.1 55403..56302(+) (comR) [Streptococcus suis isolate 861160_dxerD_hsdSA]
MNDKEFGQRVRQLRESASMTREQFCDDELELSVRQLTRIEAGASKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKNYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide

• Length: 900 bp

>NTDB_id=1155333 QNH74_RS00335 WP_074390054.1 55403..56302(+) (comR) [Streptococcus suis isolate 861160_dxerD_hsdSA]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGCTAGTATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTGCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTATGTATCTTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAACTCAAATGATTTATTTGTTCTAAGGGATACATTATTATCCTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGATAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGAATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATTGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

• Helix-turn-helix domain (HTH_31) (5-60)

• ComR tetratricopeptide (ComR_TPR) (73-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus suis P1/7	99.666	100	0.997
comR	Streptococcus suis 05ZYH33	99.666	100	0.997
comR	Streptococcus suis D9	62.126	100	0.625
comR	Streptococcus mutans UA159	43.813	100	0.438
comR	Streptococcus pyogenes MGAS315	37.374	99.331	0.371