Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   AD178_RS08605 Genome accession   NZ_OX244288
Coordinates   1687276..1687935 (+) Length   219 a.a.
NCBI ID   WP_000565016.1    Uniprot ID   A0A4J1SBP5
Organism   Streptococcus pneumoniae strain PT8105 isolate 2RLC4     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1682276..1692935
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AD178_RS08580 (SAMEA1463109_01730) - 1682581..1682898 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  AD178_RS08585 (SAMEA1463109_01731) - 1682913..1683809 (-) 897 WP_000825668.1 PEP phosphonomutase -
  AD178_RS08590 (SAMEA1463109_01732) - 1683812..1685074 (-) 1263 WP_000413336.1 PTS sugar transporter subunit IIC -
  AD178_RS08595 (SAMEA1463109_01733) - 1685354..1686532 (+) 1179 WP_000175872.1 ROK family transcriptional regulator -
  AD178_RS08600 (SAMEA1463109_01734) - 1686760..1687206 (-) 447 WP_000155412.1 GNAT family N-acetyltransferase -
  AD178_RS08605 (SAMEA1463109_01735) cclA/cilC 1687276..1687935 (+) 660 WP_000565016.1 A24 family peptidase Machinery gene
  AD178_RS08610 (SAMEA1463109_01736) trpA 1687907..1688683 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  AD178_RS08615 (SAMEA1463109_01737) trpB 1688676..1689899 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  AD178_RS08620 (SAMEA1463109_01738) - 1689877..1690476 (-) 600 WP_000169872.1 phosphoribosylanthranilate isomerase -
  AD178_RS08625 (SAMEA1463109_01739) trpC 1690463..1691230 (-) 768 WP_000076544.1 indole-3-glycerol phosphate synthase TrpC -
  AD178_RS08630 (SAMEA1463109_01740) trpD 1691227..1692231 (-) 1005 WP_000658684.1 anthranilate phosphoribosyltransferase -
  AD178_RS08635 (SAMEA1463109_01741) - 1692242..1692808 (-) 567 WP_000601921.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24835.94 Da        Isoelectric Point: 7.6418

>NTDB_id=1154335 AD178_RS08605 WP_000565016.1 1687276..1687935(+) (cclA/cilC) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1154335 AD178_RS08605 WP_000565016.1 1687276..1687935(+) (cclA/cilC) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4J1SBP5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae TIGR4

95.89

100

0.959
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

86.758

100

0.868

Multiple sequence alignment