Detailed information NTG1154320

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: AD178_RS04935
• Genome accession: NZ_OX244288
• Coordinates: 959145..960098 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain PT8105 isolate 2RLC4
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 954145..965098

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AD178_RS04910	rpmG	954888..955037 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
AD178_RS04915 (SAMEA1463109_00988)	secG	955077..955310 (+)	234	WP_000282519.1	preprotein translocase subunit SecG	-
AD178_RS04920 (SAMEA1463109_00989)	rnr	955412..957766 (+)	2355	WP_000654889.1	ribonuclease R	-
AD178_RS04925 (SAMEA1463109_00990)	smpB	957729..958196 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
AD178_RS04930 (SAMEA1463109_00991)	tehB	958212..959072 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
AD178_RS04935 (SAMEA1463109_00992)	coiA	959145..960098 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
AD178_RS04940 (SAMEA1463109_00993)	pepF	960117..961919 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
AD178_RS04945 (SAMEA1463109_00994)	-	961921..962634 (+)	714	WP_000230399.1	O-methyltransferase	-
AD178_RS04950 (SAMEA1463109_00995)	prsA	962701..963642 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
AD178_RS04955 (SAMEA1463109_00996)	-	963761..964102 (-)	342	Protein_979	IS3 family transposase	-
AD178_RS04960	-	964516..964611 (+)	96	Protein_980	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=1154320 AD178_RS04935 WP_000495911.1 959145..960098(+) (coiA) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1154320 AD178_RS04935 WP_000495911.1 959145..960098(+) (coiA) [Streptococcus pneumoniae strain PT8105 isolate 2RLC4]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435