Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   NB068_RS06060 Genome accession   NZ_OW969598
Coordinates   1236440..1237300 (+) Length   286 a.a.
NCBI ID   WP_250314386.1    Uniprot ID   -
Organism   Neisseria sp. Marseille-Q6792     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1231440..1242300
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NB068_RS06045 dapD 1232103..1232924 (-) 822 WP_107862922.1 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase -
  NB068_RS06050 pgi 1233133..1234776 (-) 1644 WP_250314384.1 glucose-6-phosphate isomerase -
  NB068_RS06055 pilG 1235134..1236366 (+) 1233 WP_250314385.1 type II secretion system F family protein Machinery gene
  NB068_RS06060 pilD 1236440..1237300 (+) 861 WP_250314386.1 A24 family peptidase Machinery gene
  NB068_RS06065 coaE 1237302..1237934 (+) 633 WP_250314387.1 dephospho-CoA kinase -
  NB068_RS06070 yacG 1237927..1238136 (+) 210 WP_250314388.1 DNA gyrase inhibitor YacG -
  NB068_RS06075 pilF 1238229..1239905 (-) 1677 WP_250314389.1 type IV-A pilus assembly ATPase PilB Machinery gene
  NB068_RS06080 - 1239902..1240174 (-) 273 WP_250314390.1 hypothetical protein -
  NB068_RS06090 - 1240437..1240883 (-) 447 WP_250314391.1 DUF441 domain-containing protein -
  NB068_RS06095 - 1240888..1241862 (-) 975 WP_250314392.1 polyprenyl synthetase family protein -

Sequence

Protein


Download         Length: 286 a.a.        Molecular weight: 31230.14 Da        Isoelectric Point: 8.2342

>NTDB_id=1153542 NB068_RS06060 WP_250314386.1 1236440..1237300(+) (pilD) [Neisseria sp. Marseille-Q6792]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVIMERGWTVFAKEHLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLHGKCASCQTKISIRYPSIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide


Download         Length: 861 bp        

>NTDB_id=1153542 NB068_RS06060 WP_250314386.1 1236440..1237300(+) (pilD) [Neisseria sp. Marseille-Q6792]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTCGGTTTATTGGTCGGAAGTTTCTTAAA
CGTCGTCATTTACCGCGTGCCGGTCATAATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAACCGGATTCCTGCTGCCCCAAATGCCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCACGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTACCC
CTCTATCGAGCTGCTGACCGGTGTATTGTTCGGGCTGGTTGCCTGGCAATACGGCTGGTCTTGGATTACATTGGGCGGTT
TGATACTGACTGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCATTATGGCTCTTATGTGCGGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGATGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(134-242)

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(17-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Neisseria gonorrhoeae MS11

97.193

99.65

0.969
  pilD Vibrio cholerae strain A1552

45.486

100

0.458
  pilD Vibrio campbellii strain DS40M4

46.014

96.503

0.444
  pilD Acinetobacter baumannii D1279779

46.97

92.308

0.434
  pilD Acinetobacter nosocomialis M2

46.97

92.308

0.434

Multiple sequence alignment