Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   LSO75_RS03665 Genome accession   NZ_OV040584
Coordinates   715134..715826 (+) Length   230 a.a.
NCBI ID   WP_038440789.1    Uniprot ID   A0AAJ8WR53
Organism   Haemophilus influenzae isolate KR271     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 710134..720826
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LSO75_RS03645 (KRLU271_LOCUS688) ampD 711411..711965 (-) 555 WP_044364862.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  LSO75_RS03650 (KRLU271_LOCUS689) pilA 712080..712529 (+) 450 WP_044364865.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  LSO75_RS03655 (KRLU271_LOCUS690) pilB 712526..713920 (+) 1395 WP_044364868.1 GspE/PulE family protein Machinery gene
  LSO75_RS03660 (KRLU271_LOCUS691) pilC 713917..715137 (+) 1221 WP_011271971.1 type II secretion system F family protein Machinery gene
  LSO75_RS03665 (KRLU271_LOCUS692) pilD 715134..715826 (+) 693 WP_038440789.1 prepilin peptidase Machinery gene
  LSO75_RS03670 (KRLU271_LOCUS693) rho 715880..717142 (-) 1263 WP_005629550.1 transcription termination factor Rho -
  LSO75_RS03675 (KRLU271_LOCUS694) metJ 717390..717707 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  LSO75_RS03680 (KRLU271_LOCUS695) cueR 717721..718107 (-) 387 WP_005663006.1 Cu(I)-responsive transcriptional regulator -
  LSO75_RS03685 (KRLU271_LOCUS696) - 718184..718390 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  LSO75_RS03690 (KRLU271_LOCUS697) - 718476..718682 (+) 207 WP_005648955.1 heavy-metal-associated domain-containing protein -
  LSO75_RS03695 (KRLU271_LOCUS698) - 718768..718974 (+) 207 WP_012054944.1 heavy-metal-associated domain-containing protein -
  LSO75_RS03700 (KRLU271_LOCUS699) - 719060..719266 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26786.77 Da        Isoelectric Point: 8.6895

>NTDB_id=1151742 LSO75_RS03665 WP_038440789.1 715134..715826(+) (pilD) [Haemophilus influenzae isolate KR271]
MIYFTMFLLGGILGIALWFYLSGFITHLQQEIYATYVELFPQNSSPFQPHFASIQQKKCGHILRYFFSIGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGTDNNFSLLTLSESIKSAAIFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHRKKKEFLPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1151742 LSO75_RS03665 WP_038440789.1 715134..715826(+) (pilD) [Haemophilus influenzae isolate KR271]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACGCA
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACAGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTTAGTATTGGGGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGCACAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTATTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAGAAAGAAAAAAGAATTTTTACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

97.391

100

0.974
  pilD Haemophilus influenzae Rd KW20

95.652

100

0.957

Multiple sequence alignment