Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   DXE48_RS13515 Genome accession   NZ_LT992473
Coordinates   2670192..2670662 (+) Length   156 a.a.
NCBI ID   WP_000610648.1    Uniprot ID   A0A090M1W2
Organism   Staphylococcus aureus isolate 14_5418     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 2648330..2699952 2670192..2670662 within 0


Gene organization within MGE regions


Location: 2648330..2699952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DXE48_RS13350 groES 2648330..2648614 (+) 285 WP_000917289.1 co-chaperone GroES -
  DXE48_RS13355 groL 2648690..2650306 (+) 1617 WP_000240642.1 chaperonin GroEL -
  DXE48_RS13360 - 2650847..2651026 (+) 180 WP_000201398.1 hypothetical protein -
  DXE48_RS14890 - 2651023..2651649 (+) 627 WP_000216896.1 hypothetical protein -
  DXE48_RS13380 - 2652188..2653495 (-) 1308 WP_001045074.1 TrkH family potassium uptake protein -
  DXE48_RS13390 - 2653878..2655101 (-) 1224 WP_000206618.1 ArgE/DapE family deacylase -
  DXE48_RS13395 - 2655533..2656588 (+) 1056 WP_000791397.1 leukocidin family pore-forming toxin -
  DXE48_RS13400 - 2656610..2657626 (+) 1017 WP_000595612.1 leukocidin/hemolysin toxin family protein -
  DXE48_RS13405 sph 2657888..2658712 (-) 825 Protein_2535 sphingomyelin phosphodiesterase -
  DXE48_RS13410 - 2658769..2659806 (-) 1038 WP_000857191.1 tyrosine-type recombinase/integrase -
  DXE48_RS13415 - 2659879..2660328 (-) 450 WP_231915586.1 hypothetical protein -
  DXE48_RS13420 - 2660428..2660610 (-) 183 WP_000705248.1 hypothetical protein -
  DXE48_RS13425 - 2660814..2661155 (-) 342 WP_000591749.1 hypothetical protein -
  DXE48_RS13430 - 2661161..2662093 (-) 933 WP_000759682.1 exonuclease domain-containing protein -
  DXE48_RS13435 - 2662109..2662822 (-) 714 WP_001031454.1 XRE family transcriptional regulator -
  DXE48_RS13440 - 2662785..2662958 (+) 174 WP_001801500.1 hypothetical protein -
  DXE48_RS13445 - 2662955..2663236 (+) 282 WP_000854074.1 helix-turn-helix transcriptional regulator -
  DXE48_RS13450 - 2663233..2663448 (+) 216 WP_001025404.1 Thoeris anti-defense Tad2 family protein -
  DXE48_RS13455 - 2663437..2663766 (-) 330 WP_000128907.1 hypothetical protein -
  DXE48_RS13460 - 2663817..2664569 (+) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  DXE48_RS13465 - 2664585..2664782 (+) 198 WP_001148862.1 hypothetical protein -
  DXE48_RS13470 - 2664769..2665149 (-) 381 WP_000762519.1 DUF2513 domain-containing protein -
  DXE48_RS13475 - 2665204..2665527 (+) 324 WP_001120201.1 DUF771 domain-containing protein -
  DXE48_RS13480 - 2665524..2665685 (+) 162 WP_000048129.1 DUF1270 family protein -
  DXE48_RS13485 - 2665780..2666082 (+) 303 WP_000165371.1 DUF2482 family protein -
  DXE48_RS13490 - 2666087..2666347 (+) 261 WP_000291510.1 DUF1108 family protein -
  DXE48_RS13495 - 2666356..2666619 (+) 264 WP_001205732.1 hypothetical protein -
  DXE48_RS13500 - 2666628..2668571 (+) 1944 WP_000700555.1 AAA family ATPase -
  DXE48_RS13505 - 2668573..2669493 (+) 921 WP_000138475.1 recombinase RecT -
  DXE48_RS13510 - 2669574..2670191 (+) 618 WP_114636105.1 MBL fold metallo-hydrolase -
  DXE48_RS13515 ssbA 2670192..2670662 (+) 471 WP_000610648.1 single-stranded DNA-binding protein Machinery gene
  DXE48_RS13520 - 2670692..2671585 (+) 894 WP_000148321.1 DnaD domain protein -
  DXE48_RS13525 - 2671592..2671810 (+) 219 WP_000338530.1 hypothetical protein -
  DXE48_RS13530 - 2671819..2672223 (+) 405 WP_114636106.1 RusA family crossover junction endodeoxyribonuclease -
  DXE48_RS13535 - 2672236..2672604 (+) 369 WP_000101288.1 SA1788 family PVL leukocidin-associated protein -
  DXE48_RS13540 - 2672608..2672850 (+) 243 WP_000131370.1 SAV1978 family virulence-associated passenger protein -
  DXE48_RS13545 - 2672865..2673119 (+) 255 WP_001065097.1 DUF1024 family protein -
  DXE48_RS14895 - 2673106..2673276 (+) 171 WP_000714403.1 hypothetical protein -
  DXE48_RS13550 - 2673269..2673805 (+) 537 WP_001066447.1 dUTP diphosphatase -
  DXE48_RS13555 - 2673842..2674087 (+) 246 WP_001282074.1 hypothetical protein -
  DXE48_RS13560 - 2674084..2674290 (+) 207 WP_076686084.1 DUF1381 domain-containing protein -
  DXE48_RS13565 - 2674287..2674673 (+) 387 WP_000592207.1 hypothetical protein -
  DXE48_RS13570 rinB 2674670..2674819 (+) 150 WP_000595265.1 transcriptional activator RinB -
  DXE48_RS13575 - 2674819..2675019 (+) 201 WP_001622114.1 DUF1514 family protein -
  DXE48_RS13580 - 2675047..2675463 (+) 417 WP_000590122.1 hypothetical protein -
  DXE48_RS13585 - 2675695..2675994 (+) 300 WP_000988336.1 HNH endonuclease -
  DXE48_RS13590 - 2676126..2676470 (+) 345 WP_000402904.1 hypothetical protein -
  DXE48_RS13595 - 2676467..2678128 (+) 1662 WP_000625088.1 terminase large subunit -
  DXE48_RS13600 - 2678144..2679331 (+) 1188 WP_000025274.1 phage portal protein -
  DXE48_RS13605 - 2679315..2680052 (+) 738 WP_000642728.1 head maturation protease, ClpP-related -
  DXE48_RS13610 - 2680076..2681221 (+) 1146 WP_000154559.1 phage major capsid protein -
  DXE48_RS13615 - 2681241..2681525 (+) 285 WP_000238236.1 hypothetical protein -
  DXE48_RS13620 - 2681515..2681799 (+) 285 WP_000150936.1 phage head-tail adapter protein -
  DXE48_RS13625 - 2681783..2682145 (+) 363 WP_000755150.1 head-tail adaptor protein -
  DXE48_RS13630 - 2682142..2682546 (+) 405 WP_114636107.1 HK97 gp10 family phage protein -
  DXE48_RS13635 - 2682543..2682950 (+) 408 WP_000565498.1 hypothetical protein -
  DXE48_RS13640 - 2682951..2683595 (+) 645 WP_000268733.1 major tail protein -
  DXE48_RS13645 - 2683649..2683861 (+) 213 WP_078101489.1 Ig-like domain-containing protein -
  DXE48_RS13650 gpG 2683911..2684261 (+) 351 WP_001096355.1 phage tail assembly chaperone G -
  DXE48_RS15110 gpGT 2684312..2684449 (+) 138 WP_001549167.1 phage tail assembly chaperone GT -
  DXE48_RS13655 - 2684506..2689035 (+) 4530 WP_001796452.1 phage tail tape measure protein -
  DXE48_RS13660 - 2689032..2690516 (+) 1485 WP_000567408.1 phage distal tail protein -
  DXE48_RS13665 - 2690532..2694317 (+) 3786 WP_000582165.1 phage tail spike protein -
  DXE48_RS13670 - 2694307..2694459 (+) 153 WP_001153681.1 hypothetical protein -
  DXE48_RS13675 - 2694506..2694793 (+) 288 WP_001040261.1 hypothetical protein -
  DXE48_RS13680 - 2694851..2695147 (+) 297 WP_000539688.1 DUF2951 domain-containing protein -
  DXE48_RS13685 pepG1 2695339..2695473 (+) 135 WP_000226108.1 type I toxin-antitoxin system toxin PepG1 -
  DXE48_RS13690 - 2695526..2695633 (-) 108 WP_001791821.1 hypothetical protein -
  DXE48_RS13695 - 2695685..2695939 (+) 255 WP_000611512.1 phage holin -
  DXE48_RS13700 - 2695951..2696706 (+) 756 WP_000861038.1 CHAP domain-containing protein -
  DXE48_RS13705 sak 2696897..2697388 (+) 492 WP_000919350.1 staphylokinase -
  DXE48_RS13715 - 2698035..2698373 (+) 339 Protein_2598 SH3 domain-containing protein -
  DXE48_RS13720 - 2698468..2698917 (-) 450 WP_000727649.1 chemotaxis-inhibiting protein CHIPS -
  DXE48_RS13725 scn 2699602..2699952 (+) 351 WP_000702263.1 complement inhibitor SCIN-A -

Sequence


Protein


Download         Length: 156 a.a.        Molecular weight: 17641.52 Da        Isoelectric Point: 5.2672

>NTDB_id=1149971 DXE48_RS13515 WP_000610648.1 2670192..2670662(+) (ssbA) [Staphylococcus aureus isolate 14_5418]
MINRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTR
NYENKEGQRVYVTEVIADSIQFLEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKPVKDNPFANANGPIELNDDDLPF

Nucleotide


Download         Length: 471 bp        

>NTDB_id=1149971 DXE48_RS13515 WP_000610648.1 2670192..2670662(+) (ssbA) [Staphylococcus aureus isolate 14_5418]
ATGATAAACAGAACAATATTAGTTGGTCGTTTAACTAGAGACCCAGAATTAAGGACCACTCAAAGTGGTGTAAATGTAGC
ATCATTCACATTAGCAGTTAACCGTACATTTACAAATGCACAAGGCGAGCGCGAGGCAGACTTTATTAATATCATCGTAT
TTAAAAAACAAGCAGAGAACGTTAATAAATACCTATCTAAAGGATCGTTGGCGGGCGTAGATGGTAGGTTACAAACGCGG
AACTATGAAAATAAGGAAGGTCAACGTGTATACGTTACGGAAGTTATTGCTGATAGTATTCAATTTTTAGAACCGAAAAA
CTCAAATGACACTCAACAAGATTTATATCAACAACAAGTACAACAAACACGTGGACAATCGCAATATTCAAATAACAAAC
CAGTAAAAGATAATCCGTTTGCGAATGCAAATGGTCCGATTGAACTAAATGATGATGATTTACCATTCTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB A0A090M1W2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

55.367

100

0.628

  ssb Latilactobacillus sakei subsp. sakei 23K

51.176

100

0.558

  ssbB Bacillus subtilis subsp. subtilis str. 168

59.434

67.949

0.404

  ssb Glaesserella parasuis strain SC1401

32.768

100

0.372


Multiple sequence alignment