Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   CKV85_RS02310 Genome accession   NZ_LT906454
Coordinates   483824..484513 (+) Length   229 a.a.
NCBI ID   WP_017770836.1    Uniprot ID   A0A239WNP0
Organism   Streptococcus acidominimus strain NCTC11291     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 478824..489513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV85_RS02285 (SAMEA4504048_00479) ktrA 479208..479879 (-) 672 WP_017770831.1 potassium uptake transporter gating subunit KtrA -
  CKV85_RS02290 (SAMEA4504048_00480) - 479899..481272 (-) 1374 WP_095121828.1 TrkH family potassium uptake protein -
  CKV85_RS02295 (SAMEA4504048_00481) rsmG 481293..482006 (-) 714 WP_017770833.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  CKV85_RS02300 (SAMEA4504048_00482) htpX 482120..483034 (+) 915 WP_017770834.1 zinc metalloprotease HtpX -
  CKV85_RS02305 (SAMEA4504048_00483) - 483055..483594 (+) 540 WP_095121830.1 DUF177 domain-containing protein -
  CKV85_RS02310 (SAMEA4504048_00484) covR 483824..484513 (+) 690 WP_017770836.1 response regulator transcription factor Regulator
  CKV85_RS02315 (SAMEA4504048_00485) - 484494..486005 (+) 1512 WP_017770837.1 HAMP domain-containing sensor histidine kinase -
  CKV85_RS02320 (SAMEA4504048_00486) nrdR 486258..486737 (+) 480 WP_017770838.1 transcriptional regulator NrdR -
  CKV85_RS02325 (SAMEA4504048_00487) - 486734..487909 (+) 1176 WP_095121831.1 DnaD domain protein -
  CKV85_RS02330 (SAMEA4504048_00488) dnaI 487912..488814 (+) 903 WP_017770840.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26470.31 Da        Isoelectric Point: 5.2594

>NTDB_id=1147478 CKV85_RS02310 WP_017770836.1 483824..484513(+) (covR) [Streptococcus acidominimus strain NCTC11291]
MTKHILIIEDEKNLSRFVSLELQHEGYSVTVEHSGRAGLESALEKDYDLILLDLMLPEMDGFEITRRLQQEKSTYIIMMT
ARDSVMDIVSGLDRGADDYIIKPFAIEELLARVRAAFRRQEIEDSKRAKTGGASYRDLKLDPQNRSVVRGEETIPLTKRE
FDLLSALMSNMNRVMTREELLNHVWKYDEAVETNVVDVYVRYLRGKIDVSGKESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 690 bp        

>NTDB_id=1147478 CKV85_RS02310 WP_017770836.1 483824..484513(+) (covR) [Streptococcus acidominimus strain NCTC11291]
ATGACGAAACATATTTTGATTATAGAAGATGAAAAAAATCTTTCACGATTTGTTTCTTTAGAATTACAACATGAAGGGTA
CTCTGTTACCGTTGAACATAGTGGCCGTGCTGGTCTTGAGTCAGCTTTGGAAAAAGATTATGATTTGATTTTGCTGGATT
TGATGTTGCCTGAAATGGATGGCTTTGAAATTACACGACGTTTACAGCAGGAAAAATCAACCTATATTATCATGATGACT
GCTCGTGATTCTGTGATGGATATTGTGTCTGGCTTAGATCGTGGTGCAGATGATTATATTATTAAGCCTTTTGCGATTGA
AGAGTTACTTGCGCGTGTTCGGGCAGCCTTTCGTCGTCAAGAAATCGAGGATAGTAAACGGGCTAAAACTGGCGGAGCTA
GCTACCGTGACCTGAAATTGGATCCTCAAAATCGCTCAGTTGTTCGTGGTGAGGAAACCATTCCTTTGACGAAAAGAGAA
TTCGATTTGTTGTCGGCATTGATGTCTAATATGAATCGCGTTATGACTCGTGAAGAGTTGCTAAACCATGTTTGGAAATA
TGATGAAGCTGTCGAAACCAATGTGGTTGATGTCTATGTCCGCTACTTGCGTGGCAAGATAGATGTCAGTGGTAAAGAGT
CGTACATTCAAACAGTGCGTGGTATGGGATATGTCATTCGTGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(152-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A239WNP0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

80.349

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.812

100

0.668
  vicR Streptococcus mutans UA159

42.424

100

0.428
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.424

Multiple sequence alignment