Detailed information NTG1147464

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CKV85_RS00330
• Genome accession: NZ_LT906454
• Coordinates: 55966..56874 (+)
• Length: 302 a.a.
• NCBI ID: WP_095121251.1
• Uniprot ID: -
• Organism: Streptococcus acidominimus strain NCTC11291
• Function: activate transcription of comX (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	56996..59174	55966..56874	flank	122

Gene organization within MGE regions

Location: 55966..59174

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV85_RS00330 (SAMEA4504048_00065)	comR	55966..56874 (+)	909	WP_095121251.1	helix-turn-helix domain-containing protein	Regulator
CKV85_RS00335	-	56996..58284 (+)	1289	Protein_44	IS1182 family transposase	-
CKV85_RS00340	-	58327..59174 (+)	848	WP_095121255.1	IS630 family transposase	-

Sequence

Protein

• Length: 302 a.a.
• Molecular weight: 35945.33 Da
• Isoelectric Point: 4.5120

>NTDB_id=1147464 CKV85_RS00330 WP_095121251.1 55966..56874(+) (comR) [Streptococcus acidominimus strain NCTC11291]
MLKNFGIKVKQLRMDKGMTREEFCEDESELSVRQLARIELGDSLPNLKKAIFIAKRLNIMLSILTDGETLELPKEYLKLK
HYIIKIPTYSDSERLATKENYFDLIYEEYYDNLPEVEKLVIDTLQATHDSLVTENFNFGAGILGDYFEQLKRKVRFDEND
LVLINLYLTYLDLEGFDGEFSDEYFYDGLFEYFKNQFQDFTIDELIILNQVLITMYALVLKNKSLTKMEEILKMIDHIME
RTKDFSRLPIQKILEWKYQLCIEENESRAKDSYNKALLFAQMTDDKYLEEQLIVEWNKDTKK

Nucleotide

• Length: 909 bp

>NTDB_id=1147464 CKV85_RS00330 WP_095121251.1 55966..56874(+) (comR) [Streptococcus acidominimus strain NCTC11291]
ATGTTAAAGAATTTTGGAATAAAAGTAAAACAATTACGTATGGATAAAGGAATGACTAGAGAAGAGTTTTGTGAAGATGA
ATCTGAATTGTCAGTTCGTCAATTGGCTAGAATTGAGCTAGGTGACTCTCTACCAAATTTAAAAAAAGCTATATTTATAG
CGAAACGACTGAATATCATGTTGAGTATTTTAACTGATGGTGAAACTTTGGAATTACCTAAAGAGTATTTAAAATTAAAA
CACTACATCATAAAAATTCCAACTTATTCAGATAGTGAGCGCTTGGCTACAAAAGAAAATTATTTTGATCTGATCTATGA
AGAGTATTATGATAATCTTCCAGAAGTTGAAAAACTAGTAATAGATACCTTGCAAGCAACGCATGATTCTCTTGTTACAG
AAAATTTCAATTTTGGTGCAGGTATTCTAGGTGACTATTTTGAACAATTAAAGAGAAAAGTACGGTTTGATGAAAATGAT
CTAGTTTTAATAAATTTATATTTAACATACTTAGATTTAGAAGGATTTGACGGAGAATTTTCAGACGAATATTTTTATGA
TGGTCTATTTGAGTATTTTAAAAATCAATTTCAGGACTTCACTATAGATGAATTAATTATTCTTAATCAAGTGCTGATAA
CAATGTATGCTCTTGTGCTAAAAAATAAAAGTTTAACAAAGATGGAAGAAATCCTTAAGATGATAGATCATATTATGGAA
AGAACAAAGGATTTTAGTCGGTTACCAATACAAAAAATCTTAGAGTGGAAATATCAGCTATGTATTGAAGAAAATGAATC
TCGTGCAAAAGATAGCTATAATAAAGCATTGCTATTTGCCCAAATGACAGATGATAAGTACTTAGAAGAACAACTTATTG
TTGAATGGAACAAGGATACTAAAAAGTGA

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix (HTH_3) (9-59)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	53.821	99.669	0.536
comR	Streptococcus mutans UA159	45.515	99.669	0.454
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	46.021	95.695	0.44
comR	Streptococcus pyogenes MGAS315	43.478	99.007	0.43