Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   CKV78_RS10195 Genome accession   NZ_LT906448
Coordinates   2228671..2229966 (+) Length   431 a.a.
NCBI ID   WP_005764897.1    Uniprot ID   C9PM32
Organism   Pasteurella dagmatis strain NCTC11617     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2223671..2234966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CKV78_RS10175 (SAMEA4362423_02078) - 2226371..2227147 (+) 777 WP_081442243.1 hypothetical protein -
  CKV78_RS10180 (SAMEA4362423_02079) - 2227173..2227679 (+) 507 WP_005764891.1 PilN domain-containing protein -
  CKV78_RS10185 (SAMEA4362423_02080) - 2227713..2228264 (+) 552 WP_005764893.1 hypothetical protein -
  CKV78_RS10190 (SAMEA4362423_02081) - 2228270..2228662 (+) 393 WP_005764895.1 pilus assembly protein PilP -
  CKV78_RS10195 (SAMEA4362423_02082) comE 2228671..2229966 (+) 1296 WP_005764897.1 type IV pilus secretin PilQ Machinery gene
  CKV78_RS10200 (SAMEA4362423_02083) aroK 2230216..2230743 (+) 528 WP_005764899.1 shikimate kinase AroK -
  CKV78_RS10205 (SAMEA4362423_02084) aroB 2230768..2231856 (+) 1089 WP_005764902.1 3-dehydroquinate synthase -
  CKV78_RS10210 (SAMEA4362423_02085) - 2231862..2232755 (+) 894 WP_005764905.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  CKV78_RS10215 (SAMEA4362423_02086) - 2232838..2233146 (-) 309 WP_005764907.1 DciA family protein -
  CKV78_RS10220 (SAMEA4362423_02087) secM 2233238..2233552 (+) 315 WP_032855657.1 secA translation cis-regulator SecM -

Sequence

Protein


Download         Length: 431 a.a.        Molecular weight: 47851.06 Da        Isoelectric Point: 6.7735

>NTDB_id=1147376 CKV78_RS10195 WP_005764897.1 2228671..2229966(+) (comE) [Pasteurella dagmatis strain NCTC11617]
MRILWKLVLKCSLLLLSFIQNVQAEEAERFSIRLKQAPLLPVLQQLALNQNKNVIIDDELNGSLSLQLEQTDFEAFFRAV
AKIKQLQFSKEGELYYLTQQNKPQRVEQLEYTPENADNLVTSAIKLHFAKVAEVMKSLSSGSGSLLSPQGSLSFDERSNL
LLVKDVSQSVRNIKKLVAEMDKPIEQIAIEARIVTISDESLKELGVRWGLLNPTELSHRVAGSLDANGFSQISEQLNVNF
ATSITPAGSLALQLAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTSGKNETQSVEFREAVL
GLDVTPHISKDNQILLDLVVSQNSPGARVAYGSGEIVSIDKQEINTQVVAKDGETIVLGGVFHDSMTKGVDKVPVLGDIP
MIKHLFRKQNERHQKRELVIFVTPRILKSKE

Nucleotide


Download         Length: 1296 bp        

>NTDB_id=1147376 CKV78_RS10195 WP_005764897.1 2228671..2229966(+) (comE) [Pasteurella dagmatis strain NCTC11617]
ATGCGGATATTGTGGAAGTTAGTGTTAAAGTGCAGTCTATTGTTATTGAGCTTTATACAAAATGTACAGGCGGAGGAGGC
AGAACGTTTTTCTATTCGGTTAAAACAAGCGCCGTTGTTACCAGTTTTACAACAGCTTGCCTTAAACCAAAATAAAAATG
TGATCATTGATGATGAGTTAAATGGGTCATTGTCTTTACAGCTTGAACAAACGGATTTTGAAGCATTTTTTCGTGCTGTA
GCGAAAATAAAGCAGCTTCAATTTAGCAAAGAAGGTGAGTTGTATTATTTAACTCAACAAAATAAGCCACAACGCGTTGA
ACAGCTTGAATATACGCCAGAAAATGCAGACAATCTTGTTACTTCAGCAATAAAATTGCATTTTGCAAAAGTAGCAGAAG
TCATGAAATCTTTATCGTCAGGTAGTGGTTCTTTATTGTCGCCACAGGGCAGTTTAAGTTTTGATGAGCGTAGTAATTTG
CTGTTAGTGAAAGATGTGTCGCAGTCGGTACGTAACATCAAGAAATTAGTTGCAGAAATGGATAAGCCTATTGAACAAAT
TGCCATTGAAGCTCGTATAGTTACAATTTCTGATGAAAGTCTAAAAGAGTTGGGCGTGCGTTGGGGATTATTAAATCCAA
CAGAATTGTCTCATCGTGTAGCTGGTAGTTTGGATGCGAATGGTTTTAGTCAAATTAGTGAGCAGCTAAATGTAAATTTT
GCGACTTCAATTACACCAGCAGGATCTTTAGCTTTGCAACTGGCAAAAATTAATGGGCGTTTATTAGATCTTGAGTTAAC
TGCACTTGAGCGTGAAAATAATGTAGAAATCATTGCCAGCCCACGTTTGCTTACAACTAATAAGAAAAGCGCAAGTATTA
AGCAAGGGACAGAAATTCCTTATGTTGTTACTAGTGGTAAAAATGAAACACAATCGGTGGAATTTAGAGAAGCAGTTTTA
GGTTTAGATGTCACGCCGCATATTTCTAAAGATAATCAAATTCTCTTGGATTTAGTGGTCAGTCAAAACTCACCGGGTGC
AAGAGTAGCGTATGGTTCAGGGGAGATTGTATCGATTGATAAACAAGAAATTAATACGCAGGTGGTTGCTAAAGACGGTG
AAACCATTGTGTTAGGTGGTGTATTTCACGATAGCATGACAAAAGGTGTGGATAAAGTGCCTGTTTTGGGTGATATTCCT
ATGATTAAGCATTTATTTCGTAAACAAAATGAGAGACATCAAAAGCGTGAATTGGTCATTTTTGTGACACCTAGAATTCT
CAAGTCGAAAGAATGA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(268-428)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C9PM32

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

66.207

100

0.668
  comE Haemophilus influenzae 86-028NP

65.287

100

0.659
  comE Glaesserella parasuis strain SC1401

52.019

97.68

0.508
  pilQ Vibrio campbellii strain DS40M4

40.047

99.072

0.397
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

40.094

98.376

0.394
  pilQ Vibrio cholerae strain A1552

40.094

98.376

0.394

Multiple sequence alignment