Detailed information NTG1147140

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: CKV83_RS07775
• Genome accession: NZ_LT906439
• Coordinates: 1667326..1668060 (-)
• Length: 244 a.a.
• NCBI ID: WP_018373328.1
• Uniprot ID: -
• Organism: Streptococcus merionis strain NCTC13788
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1662326..1673060

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CKV83_RS07750 (SAMEA4412692_01547)	-	1662330..1663031 (-)	702	WP_018373333.1	N-acetylmannosamine-6-phosphate 2-epimerase	-
CKV83_RS07755 (SAMEA4412692_01548)	-	1663300..1664046 (+)	747	WP_018373332.1	hypothetical protein	-
CKV83_RS07760 (SAMEA4412692_01549)	-	1664069..1664941 (+)	873	WP_018373331.1	ABC transporter ATP-binding protein	-
CKV83_RS07765 (SAMEA4412692_01550)	-	1664968..1665747 (+)	780	WP_018373330.1	hypothetical protein	-
CKV83_RS07770 (SAMEA4412692_01551)	-	1665998..1667329 (-)	1332	WP_018373329.1	sensor histidine kinase	-
CKV83_RS07775 (SAMEA4412692_01552)	comE/blpR	1667326..1668060 (-)	735	WP_018373328.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 244 a.a.
• Molecular weight: 28090.13 Da
• Isoelectric Point: 5.8731

>NTDB_id=1147140 CKV83_RS07775 WP_018373328.1 1667326..1668060(-) (comE/blpR) [Streptococcus merionis strain NCTC13788]
MLSIFVLEDDFLQQGRLERAIAETVKAGQIKCKRLEIFGKPQQLLEAVTETGDHQFFFLDIEIKGEEKKGMEIAREIREK
DPRAVIVFVTTHSEFMPLSYKYRVSALDFIDKGLSEADYQEAVSSVLEHAYANISQTVSQDAFVFKNEHSHVQVPFSDIL
YFETASTVHKVILTTKTGMLEFYGKVSEMAKLDERLYQTHRAYVVNPENVTSIDRKNFMVHFGNDESCFVSRMKLKGLIE
RVEK

Nucleotide

• Length: 735 bp

>NTDB_id=1147140 CKV83_RS07775 WP_018373328.1 1667326..1668060(-) (comE/blpR) [Streptococcus merionis strain NCTC13788]
ATGTTATCTATTTTTGTTTTAGAAGATGATTTTTTACAACAGGGACGCTTAGAGCGGGCGATTGCTGAGACGGTAAAAGC
TGGTCAGATCAAGTGCAAACGCTTGGAGATTTTTGGTAAACCGCAGCAATTGCTGGAGGCTGTGACAGAGACAGGGGACC
ACCAATTTTTCTTCTTAGATATTGAAATCAAGGGTGAGGAAAAAAAGGGCATGGAAATCGCGCGTGAGATTCGTGAAAAG
GATCCGCGTGCGGTCATCGTCTTTGTCACGACGCATTCGGAATTCATGCCCCTGTCTTACAAGTACCGTGTGTCGGCTCT
GGATTTTATTGACAAGGGCTTGAGCGAAGCTGATTATCAGGAAGCGGTCAGTTCTGTCCTTGAGCATGCTTATGCCAATA
TTAGTCAGACCGTTAGCCAAGATGCCTTTGTCTTTAAAAATGAGCACTCCCATGTTCAGGTGCCTTTTTCAGATATTCTT
TACTTTGAGACGGCATCGACTGTTCACAAGGTCATTTTGACCACCAAGACAGGCATGTTGGAATTTTACGGTAAGGTCTC
TGAAATGGCTAAGCTGGACGAGCGACTTTACCAAACACATAGAGCCTATGTGGTCAATCCTGAAAATGTGACTAGTATTG
ACCGTAAGAATTTTATGGTTCATTTTGGAAACGACGAATCTTGCTTTGTCTCTAGGATGAAACTCAAAGGCTTGATTGAG
AGGGTCGAAAAATGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-241)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.812	97.951	0.537
comE/comE1	Streptococcus equinus JB1	45.188	97.951	0.443
comE/comE2	Streptococcus equinus JB1	39.918	99.59	0.398
comE	Streptococcus infantis strain Atu-4	36.032	100	0.365