Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   KJB12_RS02275 Genome accession   NZ_LT795502
Coordinates   474600..475724 (+) Length   374 a.a.
NCBI ID   WP_000228566.1    Uniprot ID   A0A0L6XXN7
Organism   Escherichia coli strain KV7 isolate KV7     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 469600..480724
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KJB12_RS02250 mscL 469726..470136 (-) 411 WP_000022442.1 large-conductance mechanosensitive channel protein MscL -
  KJB12_RS02255 trkA 470266..471642 (-) 1377 WP_000691382.1 Trk system potassium transporter TrkA -
  KJB12_RS02260 rsmB 471664..472953 (-) 1290 WP_001313334.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  KJB12_RS02265 fmt 472999..473946 (-) 948 WP_000004459.1 methionyl-tRNA formyltransferase -
  KJB12_RS02270 def 473961..474470 (-) 510 WP_000114984.1 peptide deformylase -
  KJB12_RS02275 dprA 474600..475724 (+) 1125 WP_000228566.1 DNA-protecting protein DprA Machinery gene
  KJB12_RS02280 smg 475696..476169 (+) 474 WP_000460672.1 DUF494 family protein Smg -
  KJB12_RS02285 yrdD 476198..476740 (+) 543 WP_001313333.1 type I DNA topoisomerase -
  KJB12_RS02290 tsaC 476745..477317 (+) 573 WP_024257773.1 L-threonylcarbamoyladenylate synthase type 1 TsaC -
  KJB12_RS02295 aroE 477322..478140 (+) 819 WP_000451222.1 shikimate dehydrogenase -
  KJB12_RS02300 yrdB 478137..478394 (+) 258 WP_001070559.1 DUF1488 domain-containing protein -
  KJB12_RS02305 yrdA 478370..478924 (-) 555 WP_213222121.1 gamma carbonic anhydrase family protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 41002.96 Da        Isoelectric Point: 6.3366

>NTDB_id=1146209 KJB12_RS02275 WP_000228566.1 474600..475724(+) (dprA) [Escherichia coli strain KV7 isolate KV7]
MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLATSLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALHSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=1146209 KJB12_RS02275 WP_000228566.1 474600..475724(+) (dprA) [Escherichia coli strain KV7 isolate KV7]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGCGTCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GCTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTGGCGCATAAAGCGGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCGCGTCGCCATGCCCGACTGGCTACCAGTTTGCT
TGAACATGGTGGGGCACTTGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCACAGTGGTTCGTTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGTGAAGTTTTTGCCTTGCCAGGACCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(312-357)

DNA recombination-mediator protein A (DNA_processg_A)

(67-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0L6XXN7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.78

98.663

0.481
  dprA Vibrio cholerae strain A1552

44.595

98.93

0.441
  dprA Glaesserella parasuis strain SC1401

45.104

90.107

0.406
  dprA Haemophilus influenzae Rd KW20

44.51

90.107

0.401
  dprA Legionella pneumophila strain ERS1305867

44.242

88.235

0.39

Multiple sequence alignment