Detailed information NTG1146158

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: BQ8897_RS04690
• Genome accession: NZ_LT714196
• Coordinates: 833617..835854 (+)
• Length: 745 a.a.
• NCBI ID: WP_000902956.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae isolate BM110
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 828617..840854

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BQ8897_RS04665 (BQ8897_BM110_00907)	-	829213..830799 (+)	1587	WP_000673086.1	DEAD/DEAH box helicase	-
BQ8897_RS04670 (BQ8897_BM110_00908)	-	830982..831248 (-)	267	WP_000598735.1	GIY-YIG nuclease family protein	-
BQ8897_RS04675 (BQ8897_BM110_00909)	-	831241..832005 (-)	765	WP_000567428.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
BQ8897_RS04680 (BQ8897_BM110_00910)	-	832140..832880 (+)	741	WP_000500222.1	lysophospholipid acyltransferase family protein	-
BQ8897_RS04685 (BQ8897_BM110_00911)	-	832980..833633 (+)	654	WP_000461741.1	helix-hairpin-helix domain-containing protein	-
BQ8897_RS04690 (BQ8897_BM110_00912)	comEC/celB	833617..835854 (+)	2238	WP_000902956.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BQ8897_RS04695 (BQ8897_BM110_00913)	-	835980..836789 (+)	810	WP_000153219.1	Cof-type HAD-IIB family hydrolase	-
BQ8897_RS04700 (BQ8897_BM110_00914)	-	836800..837744 (+)	945	WP_000200834.1	LacI family DNA-binding transcriptional regulator	-
BQ8897_RS04705 (BQ8897_BM110_00915)	-	837803..838795 (-)	993	WP_000800989.1	alpha/beta hydrolase fold domain-containing protein	-
BQ8897_RS04710 (BQ8897_BM110_00916)	-	838971..839699 (+)	729	WP_000468967.1	methyltransferase domain-containing protein	-
BQ8897_RS04715 (BQ8897_BM110_00917)	holA	839753..840790 (+)	1038	WP_000560298.1	DNA polymerase III subunit delta	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 85666.56 Da
• Isoelectric Point: 9.8125

>NTDB_id=1146158 BQ8897_RS04690 WP_000902956.1 833617..835854(+) (comEC/celB) [Streptococcus agalactiae isolate BM110]
MLHLTKYFPLKPIYLALLVFQIYLLVFSWTMLGCAFLLFTFIFLIYQYDRETIFKTITIVIFFLFYFLWQNHNMNVQYQR
VPNHISQIKVRIDTISINGDVLSFQADASGNTYQAFYTLKNKSEKDYFQNLDNNIMIIADIKLEEAEERRHFNGFDYRQY
LKRHGIYRIAKVTKIKQIRLFQHRSFFDLMFKWRRSAIVISQTFPNPMRHYMSGLLFGYLDKTFDDMSDLYSSLGIIHLF
ALSGMQVGFFLGIFRYICLRIGLRLDHVWLLQIPFSLIYAGLTGFSISVVRALIQSLLSHSGVKKDENFALCLLICLISL
PHSLLTTGGVLSFAYAFILTMTSFDHFSSIKKVAIESLTVSVGILPILTYYFSGFQPISIILTALLSFAFDIIFLPLLTV
IFVLSPFVKLSCINSLFEILEVLLKWTGQLFPRPLIFGKPSLFLLIVMIIILGLLYDYYHSKCFRYCSLLIIFTLFFITK
NPITNEVAILDVGQGDSILVRDWLGKTILIDTGGRVRFEQPEEWKQKVNQSNAERTLIPYLKSRGISKIDNLVITHTDTD
HMGDMEVISKHFKVARLITSSGSLTNSQYVKRLSKIGVAVKSIEAGDKLSVMGSYLQVLYPWHKGDGKNNDSIVLYGHLL
GKGFLFTGDLEEEGEKQLLEAYPNLSVDILKAGHHGSKGSSSLSFLKKLSPSVVLVSAGKNNRYQHPHQETLQRFQKIKS
KIFRTDQSGTIRLTGWWKWHIQTVR

Nucleotide

• Length: 2238 bp

>NTDB_id=1146158 BQ8897_RS04690 WP_000902956.1 833617..835854(+) (comEC/celB) [Streptococcus agalactiae isolate BM110]
ATGTTACACTTGACTAAGTATTTTCCTCTAAAACCTATTTATTTAGCATTGTTGGTCTTCCAAATTTACTTACTAGTGTT
TTCTTGGACAATGCTTGGTTGTGCCTTTCTTTTATTTACTTTTATTTTTCTGATTTATCAATATGATCGTGAAACTATTT
TTAAAACAATAACAATAGTAATTTTTTTCTTATTTTATTTTTTATGGCAAAATCACAATATGAATGTCCAATATCAAAGA
GTACCGAATCATATTAGCCAGATTAAAGTGCGTATTGATACTATTTCTATCAATGGTGATGTTTTATCATTCCAGGCAGA
TGCTTCAGGTAACACTTATCAAGCTTTTTACACATTAAAAAATAAAAGTGAGAAAGATTATTTTCAAAATCTTGATAATA
ATATAATGATAATTGCAGATATCAAACTTGAAGAAGCAGAGGAGAGAAGGCATTTTAATGGCTTTGATTATCGTCAGTAT
TTAAAAAGACATGGAATTTATCGTATCGCCAAAGTGACAAAGATAAAACAGATACGCTTATTTCAACATAGGTCTTTCTT
TGATCTTATGTTTAAGTGGCGTAGAAGTGCAATTGTTATTAGTCAAACTTTTCCAAATCCTATGCGTCACTATATGTCAG
GGCTTTTGTTTGGATATCTAGATAAGACCTTTGATGACATGTCCGATTTATATAGTAGTCTAGGTATTATACATTTATTT
GCTTTGTCAGGTATGCAAGTAGGTTTTTTTCTCGGTATTTTTCGTTATATCTGTCTACGTATTGGCTTACGTCTAGACCA
TGTTTGGTTACTTCAAATACCATTCTCGCTAATTTATGCTGGTTTAACAGGCTTTAGTATCTCAGTCGTTAGGGCACTTA
TTCAATCTTTATTATCACATAGCGGTGTCAAGAAAGATGAGAACTTTGCTCTCTGCTTGTTAATTTGTCTTATCTCTCTC
CCCCACTCACTTTTGACTACGGGAGGAGTTCTTAGCTTTGCTTATGCTTTTATACTTACGATGACCTCCTTTGATCATTT
TTCGAGTATAAAAAAAGTAGCTATCGAATCTTTGACAGTCTCTGTAGGAATTCTTCCCATACTAACCTACTATTTTTCGG
GTTTTCAACCAATATCAATTATATTAACAGCACTTTTATCTTTTGCATTTGATATTATATTTTTGCCTTTATTAACTGTT
ATATTTGTCTTATCACCGTTCGTTAAATTAAGTTGTATTAATAGTTTGTTTGAAATCCTAGAAGTATTATTAAAATGGAC
TGGGCAACTGTTTCCAAGACCACTTATTTTTGGAAAGCCCAGCCTTTTTCTTTTAATAGTCATGATTATAATTTTGGGAT
TACTTTATGATTATTATCATTCTAAATGTTTTCGTTATTGCTCCCTTCTTATTATCTTTACCTTGTTTTTTATCACTAAG
AATCCAATTACTAACGAGGTTGCGATTTTAGATGTTGGACAAGGAGATAGTATTTTAGTGAGGGATTGGTTAGGAAAAAC
AATTTTAATTGATACTGGGGGAAGGGTGAGATTTGAACAGCCTGAAGAATGGAAACAAAAAGTAAACCAGTCTAATGCTG
AGAGAACGCTCATTCCTTACTTGAAAAGCAGAGGTATTAGCAAGATAGATAATTTAGTGATAACTCATACCGATACAGAT
CATATGGGGGATATGGAAGTTATCTCAAAGCATTTTAAAGTTGCACGTTTGATTACAAGTTCAGGTTCTTTAACGAATTC
GCAGTACGTTAAGCGTTTATCAAAGATAGGAGTAGCTGTAAAATCTATAGAAGCTGGTGATAAACTTTCTGTCATGGGAA
GTTATTTACAAGTACTTTACCCATGGCACAAGGGTGATGGAAAAAATAATGATTCAATTGTTTTATATGGACATTTATTA
GGAAAAGGCTTCTTATTTACCGGTGATTTGGAGGAAGAGGGAGAAAAGCAGTTATTAGAAGCTTATCCTAATTTATCAGT
AGATATCCTTAAAGCAGGACATCATGGTTCTAAGGGCTCATCAAGTCTATCCTTTCTGAAAAAGTTGTCTCCTAGTGTGG
TTCTAGTGTCAGCTGGTAAAAATAATCGTTACCAGCATCCTCATCAAGAGACTTTACAAAGGTTCCAAAAGATTAAAAGC
AAGATTTTCCGAACGGATCAATCAGGTACAATTAGGCTAACAGGATGGTGGAAGTGGCATATTCAGACAGTTCGTTGA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-458)

• Metallo-beta-lactamase superfamily (Lactamase_B) (491-576)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	48.262	100	0.485
comEC/celB	Streptococcus mitis NCTC 12261	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae TIGR4	46.791	100	0.47
comEC/celB	Streptococcus pneumoniae Rx1	46.319	100	0.464
comEC/celB	Streptococcus pneumoniae D39	46.319	100	0.464
comEC/celB	Streptococcus pneumoniae R6	46.319	100	0.464
comEC	Lactococcus lactis subsp. cremoris KW2	44.355	99.866	0.443