Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BUC38_RS05230 Genome accession   NZ_LT671674
Coordinates   1054631..1056010 (+) Length   459 a.a.
NCBI ID   WP_044690760.1    Uniprot ID   A0A0Z8IDY1
Organism   Streptococcus suis strain LS9N     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1049631..1061010
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUC38_RS05200 pstA 1049953..1050840 (+) 888 WP_014635996.1 phosphate ABC transporter permease PstA -
  BUC38_RS05205 pstB 1050865..1051668 (+) 804 WP_029185151.1 phosphate ABC transporter ATP-binding protein PstB -
  BUC38_RS05210 pstB 1051680..1052438 (+) 759 WP_044673059.1 phosphate ABC transporter ATP-binding protein PstB -
  BUC38_RS05215 phoU 1052467..1053123 (+) 657 WP_002940865.1 phosphate signaling complex protein PhoU -
  BUC38_RS05220 - 1053273..1053821 (+) 549 WP_032511937.1 hypothetical protein -
  BUC38_RS05225 ciaR 1053967..1054638 (+) 672 WP_029176020.1 response regulator transcription factor Regulator
  BUC38_RS05230 ciaH 1054631..1056010 (+) 1380 WP_044690760.1 HAMP domain-containing sensor histidine kinase Regulator
  BUC38_RS05235 - 1056110..1057339 (+) 1230 WP_044690763.1 transglutaminase domain-containing protein -
  BUC38_RS05240 rpsT 1057554..1057802 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  BUC38_RS05245 coaA 1057861..1058781 (-) 921 WP_002940857.1 type I pantothenate kinase -
  BUC38_RS05250 - 1058890..1059480 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  BUC38_RS05255 - 1059477..1060754 (+) 1278 WP_002940851.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51873.53 Da        Isoelectric Point: 6.1938

>NTDB_id=1146000 BUC38_RS05230 WP_044690760.1 1054631..1056010(+) (ciaH) [Streptococcus suis strain LS9N]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDVEQLKLGINTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKEATVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMINVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=1146000 BUC38_RS05230 WP_044690760.1 1054631..1056010(+) (ciaH) [Streptococcus suis strain LS9N]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAGCCAGCGATGGCTGTTGGTTTTGCAATCGCAAGAACGTATGAGCCTAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGT
AGAACAGCTGAAATTAGGTATCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCAGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAGCAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTGGCTACAGATGAACTAGGCTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCTTCCATTGAGACTTATGAATCGACAGTTGCTATTGTTATGGTTTCAG
CTTGGCTCATTTCTATCTTAGCCAGTATTTACCTATCGAATCTTAGCATGCGTCCAATTCTAATTAGCTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTGCGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTATTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGCATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCAATGTCCAACCTAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCTGAAGAAAATGGAAAAACGCTAACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTTCTGATCAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACAGACGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAACAAATTATCAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8IDY1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.46

100

0.499
  ciaH Streptococcus pneumoniae D39

49.46

100

0.499
  ciaH Streptococcus pneumoniae R6

49.46

100

0.499
  ciaH Streptococcus pneumoniae TIGR4

49.46

100

0.499
  ciaH Streptococcus mutans UA159

49.888

97.386

0.486

Multiple sequence alignment