Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   BQ3358_RS06155 Genome accession   NZ_LT615218
Coordinates   1226432..1227304 (+) Length   290 a.a.
NCBI ID   WP_000593194.1    Uniprot ID   A0A9P3DKN4
Organism   Staphylococcus aureus strain AUS0325     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1191315..1237290 1226432..1227304 within 0


Gene organization within MGE regions


Location: 1191315..1237290
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BQ3358_RS05995 - 1191761..1192504 (+) 744 WP_000888485.1 protein-serine/threonine phosphatase Stp1 -
  BQ3358_RS06000 pknB 1192501..1194495 (+) 1995 WP_031865098.1 serine/threonine protein kinase Stk1 -
  BQ3358_RS06005 rsgA 1194723..1195598 (+) 876 WP_069991953.1 ribosome small subunit-dependent GTPase A -
  BQ3358_RS06010 rpe 1195599..1196243 (+) 645 WP_000164332.1 ribulose-phosphate 3-epimerase -
  BQ3358_RS06015 - 1196250..1196891 (+) 642 WP_069991955.1 thiamine diphosphokinase -
  BQ3358_RS06020 rpmB 1197272..1197460 (-) 189 WP_000517908.1 50S ribosomal protein L28 -
  BQ3358_RS06025 - 1197903..1198277 (+) 375 WP_000171418.1 Asp23/Gls24 family envelope stress response protein -
  BQ3358_RS06030 fakA 1198292..1199938 (+) 1647 WP_000623903.1 fatty acid kinase catalytic subunit FakA -
  BQ3358_RS06035 recG 1200128..1202188 (+) 2061 WP_069991957.1 ATP-dependent DNA helicase RecG -
  BQ3358_RS06040 fapR 1202391..1202963 (+) 573 WP_001548538.1 transcription factor FapR -
  BQ3358_RS06045 plsX 1202968..1203954 (+) 987 WP_000239752.1 phosphate acyltransferase PlsX -
  BQ3358_RS06050 fabD 1203947..1204873 (+) 927 WP_000047343.1 ACP S-malonyltransferase -
  BQ3358_RS06055 fabG 1204866..1205600 (+) 735 WP_000167263.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  BQ3358_RS06065 - 1205808..1206041 (+) 234 WP_000426914.1 acyl carrier protein -
  BQ3358_RS06070 rnc 1206157..1206888 (+) 732 WP_000043237.1 ribonuclease III -
  BQ3358_RS06075 smc 1207035..1210601 (+) 3567 WP_000262701.1 chromosome segregation protein SMC -
  BQ3358_RS06080 ftsY 1210601..1211851 (+) 1251 WP_000007689.1 signal recognition particle-docking protein FtsY -
  BQ3358_RS06085 - 1211838..1212170 (+) 333 WP_000531319.1 putative DNA-binding protein -
  BQ3358_RS06090 ffh 1212196..1213563 (+) 1368 WP_000863474.1 signal recognition particle protein -
  BQ3358_RS06095 rpsP 1213998..1214273 (+) 276 WP_000268754.1 30S ribosomal protein S16 -
  BQ3358_RS06100 rimM 1214461..1214964 (+) 504 WP_001261987.1 ribosome maturation factor RimM -
  BQ3358_RS06105 trmD 1214964..1215701 (+) 738 WP_000687328.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  BQ3358_RS06110 rplS 1215804..1216154 (+) 351 WP_000181404.1 50S ribosomal protein L19 -
  BQ3358_RS06120 yfhO 1216795..1219401 (-) 2607 WP_000915227.1 lipoteichoic acid-specific glycosyltransferase YfhO -
  BQ3358_RS06125 ylqF 1219802..1220686 (+) 885 WP_000236714.1 ribosome biogenesis GTPase YlqF -
  BQ3358_RS06130 - 1220670..1221437 (+) 768 WP_000176395.1 ribonuclease HII -
  BQ3358_RS06135 sucC 1221546..1222712 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  BQ3358_RS06140 sucD 1222734..1223642 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  BQ3358_RS06145 - 1223869..1224987 (+) 1119 Protein_1186 LysM peptidoglycan-binding domain-containing protein -
  BQ3358_RS06150 fmhC 1225015..1226259 (+) 1245 WP_000672869.1 FemA/FemB family glycyltransferase FmhC -
  BQ3358_RS06155 dprA 1226432..1227304 (+) 873 WP_000593194.1 DNA-processing protein DprA Machinery gene
  BQ3358_RS06160 topA 1227478..1229553 (+) 2076 WP_001557331.1 type I DNA topoisomerase -
  BQ3358_RS06165 trmFO 1229709..1231016 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  BQ3358_RS06170 xerC 1231433..1232329 (+) 897 WP_001015597.1 tyrosine recombinase XerC -
  BQ3358_RS06175 hslV 1232326..1232871 (+) 546 WP_000072681.1 ATP-dependent protease subunit HslV -
  BQ3358_RS06180 hslU 1232937..1234340 (+) 1404 WP_000379054.1 ATP-dependent protease ATPase subunit HslU -
  BQ3358_RS06185 codY 1234365..1235138 (+) 774 WP_000055337.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  BQ3358_RS06190 - 1235189..1235281 (+) 93 WP_001790530.1 hypothetical protein -
  BQ3358_RS06195 rpsB 1235480..1236247 (+) 768 WP_000268484.1 30S ribosomal protein S2 -
  BQ3358_RS06200 - 1236281..1236394 (+) 114 WP_001789890.1 hypothetical protein -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33541.01 Da        Isoelectric Point: 9.5093

>NTDB_id=1145289 BQ3358_RS06155 WP_000593194.1 1226432..1227304(+) (dprA) [Staphylococcus aureus strain AUS0325]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVLLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=1145289 BQ3358_RS06155 WP_000593194.1 1226432..1227304(+) (dprA) [Staphylococcus aureus strain AUS0325]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCTTTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTAGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGAGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus N315

100

100

1
  dprA Staphylococcus aureus MW2

99.655

100

0.997
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae D39

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus pneumoniae R6

37.809

97.586

0.369
  dprA/cilB/dalA Streptococcus mitis SK321

37.456

97.586

0.366

Multiple sequence alignment