Detailed information NTG1143804

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A8Q77_RS07245
• Genome accession: NZ_LT571436
• Coordinates: 1571615..1572475 (-)
• Length: 286 a.a.
• NCBI ID: WP_004285616.1
• Uniprot ID: A0A448VLV4
• Organism: Neisseria weaveri strain NCTC13585
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1566615..1577475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A8Q77_RS07220 (SAMEA3174300_01446)	-	1566835..1567491 (-)	657	WP_231987914.1	phosphatase PAP2 family protein	-
A8Q77_RS07225 (SAMEA3174300_01448)	yjgA	1567990..1568505 (-)	516	WP_004282581.1	ribosome biogenesis factor YjgA	-
A8Q77_RS07230 (SAMEA3174300_01449)	pmbA	1568639..1569967 (+)	1329	WP_064130788.1	metalloprotease PmbA	-
A8Q77_RS10375 (SAMEA3174300_01450)	yacG	1570032..1570214 (-)	183	WP_081463174.1	DNA gyrase inhibitor YacG	-
A8Q77_RS07235 (SAMEA3174300_01451)	zapD	1570220..1570993 (-)	774	WP_004282578.1	cell division protein ZapD	-
A8Q77_RS07240 (SAMEA3174300_01452)	coaE	1570990..1571613 (-)	624	WP_064130789.1	dephospho-CoA kinase	-
A8Q77_RS07245 (SAMEA3174300_01453)	pilD	1571615..1572475 (-)	861	WP_004285616.1	prepilin peptidase	Machinery gene
A8Q77_RS07250 (SAMEA3174300_01454)	pilG	1572478..1573719 (-)	1242	WP_004282575.1	type II secretion system F family protein	Machinery gene
A8Q77_RS07255 (SAMEA3174300_01455)	pilF	1573743..1575422 (-)	1680	WP_004282574.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A8Q77_RS07260 (SAMEA3174300_01456)	comE	1575649..1575954 (-)	306	WP_064130790.1	ComEA family DNA-binding protein	Machinery gene

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31613.70 Da
• Isoelectric Point: 7.6384

>NTDB_id=1143804 A8Q77_RS07245 WP_004285616.1 1571615..1572475(-) (pilD) [Neisseria weaveri strain NCTC13585]
MHQLDLPIYWLLGVAAVFGLLVGSFLNVVIYRLPVMMERSWTVFSKEHLELPLSKEEKQRFDLIKPDSRCPTCHTPVRFW
QNIPVISYCILKGKCAECATPISKRYPLVELLTSVLFVIVVWQYGVSWFALGGLVLTAFLIALTFIDADTQYLPDSLTLP
LIWLGLLFNWDNGLISLQSAVLGAVLGYSALWLLCYVYRLLTGKIGMGGGDLKLLAALGAWLGVGALPVIVFLSALVGIV
VGLLMKVAKNEHFAFGPSLAIVGWLVFVANTHVSQAIDWWLNASGF

Nucleotide

• Length: 861 bp

>NTDB_id=1143804 A8Q77_RS07245 WP_004285616.1 1571615..1572475(-) (pilD) [Neisseria weaveri strain NCTC13585]
ATGCATCAACTCGACTTGCCAATCTATTGGTTATTGGGGGTGGCAGCAGTTTTCGGTTTGTTAGTCGGCAGTTTTTTAAA
TGTTGTCATTTATCGTTTGCCGGTGATGATGGAACGGAGTTGGACTGTATTTTCTAAGGAGCACTTAGAGCTTCCCTTAT
CTAAAGAAGAAAAACAGCGTTTTGATTTGATTAAACCTGATTCACGTTGCCCTACTTGCCATACACCTGTCAGATTTTGG
CAGAATATTCCGGTAATCAGCTATTGTATTCTGAAAGGAAAATGCGCCGAATGCGCCACGCCGATCAGTAAGCGGTATCC
GTTGGTTGAATTGTTGACATCGGTTTTATTTGTCATTGTCGTTTGGCAGTATGGAGTGAGTTGGTTCGCTCTAGGTGGTT
TGGTGCTTACAGCTTTTTTGATTGCTTTGACGTTTATTGATGCCGATACTCAATATTTGCCCGATTCGCTGACATTACCT
CTCATATGGCTGGGTTTATTATTTAATTGGGACAATGGTTTGATATCCTTGCAGTCTGCTGTTTTGGGTGCGGTGTTGGG
ATATTCCGCTCTGTGGTTATTGTGTTACGTTTACCGATTATTAACAGGTAAGATAGGCATGGGTGGCGGTGATTTGAAAT
TATTGGCCGCTTTAGGTGCATGGTTGGGTGTGGGAGCTTTGCCTGTTATAGTGTTTTTGTCTGCTTTGGTCGGTATAGTG
GTCGGTCTGCTGATGAAGGTGGCAAAAAACGAGCATTTTGCTTTTGGACCGAGTCTTGCGATAGTGGGATGGTTGGTTTT
TGTTGCAAATACCCATGTATCACAAGCTATAGATTGGTGGTTGAACGCTTCGGGATTCTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-243)

3D structure

• AlphaFold DB: A0A448VLV4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	69.145	94.056	0.65
pilD	Vibrio cholerae strain A1552	46.786	97.902	0.458
pilD	Acinetobacter baumannii D1279779	49.807	90.559	0.451
pilD	Acinetobacter nosocomialis M2	49.421	90.559	0.448
pilD	Vibrio campbellii strain DS40M4	45.714	97.902	0.448