Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   DQN68_RS01365 Genome accession   NZ_LS483522
Coordinates   247427..249397 (+) Length   656 a.a.
NCBI ID   WP_002992224.1    Uniprot ID   A0A5S4TJC7
Organism   Streptococcus pyogenes strain NCTC8224     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 242427..254397
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN68_RS01345 (NCTC8224_00268) sufU 242473..242952 (+) 480 WP_002986018.1 Fe-S cluster assembly sulfur transfer protein SufU -
  DQN68_RS01350 (NCTC8224_00269) sufB 242945..244363 (+) 1419 WP_002986015.1 Fe-S cluster assembly protein SufB -
  DQN68_RS01355 (NCTC8224_00270) - 244515..245696 (-) 1182 WP_002992220.1 D-alanyl-D-alanine carboxypeptidase family protein -
  DQN68_RS01360 (NCTC8224_00271) pbp3 245864..247096 (-) 1233 WP_002991111.1 D-alanyl-D-alanine carboxypeptidase PBP3 -
  DQN68_RS01365 (NCTC8224_00272) amiA 247427..249397 (+) 1971 WP_002992224.1 peptide ABC transporter substrate-binding protein Regulator
  DQN68_RS01370 (NCTC8224_00273) amiC 249462..250964 (+) 1503 WP_011017334.1 ABC transporter permease Regulator
  DQN68_RS01375 (NCTC8224_00274) amiD 250964..251890 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  DQN68_RS01380 (NCTC8224_00275) amiE 251899..252969 (+) 1071 WP_002992231.1 ABC transporter ATP-binding protein Regulator
  DQN68_RS01385 (NCTC8224_00276) amiF 252962..253885 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  DQN68_RS09690 - 253923..254012 (-) 90 WP_109821088.1 IS3 family transposase -
  DQN68_RS09425 - 254033..254212 (-) 180 WP_014635282.1 hypothetical protein -

Sequence

Protein


Download         Length: 656 a.a.        Molecular weight: 72033.45 Da        Isoelectric Point: 5.1180

>NTDB_id=1142872 DQN68_RS01365 WP_002992224.1 247427..249397(+) (amiA) [Streptococcus pyogenes strain NCTC8224]
MKKSKWLAAVSVAILSVSALAACGNKNASGGSEATKTYKYVFVNDPKSLDYILTNGGGTTDVITQMVDGLLENDEYGNLV
PSLAKDWKVSKDGLTYTYTLRDGVSWYTADGEEYAPVTAEDFVTGLKHAVDDKSDALYVVEDSIKNLKAYQNGEVDFKEV
GVKALDDKTVQYTLNKPESYWNSKTTYSVLFPVNAKFLKSKGKDFGTTDPSSILVNGAYFLSAFTSKSSMEFHKNENYWD
AKNVGIESVKLTYSDGSDPGSFYKNFDKGEFSVARLYPNDPTYKSAKKNYADNITYGMLTGDIRHLTWNLNRTSFKNTKK
DPAQQDAGKKALNNKDFRQAIQFAFDRASFQAQTAGQDAKTKALRNMLVPPTFVTIGESDFGSEVEKEMAKLGDEWKDVN
LADAQDGFYNPEKAKAEFAKAKEALTAEGVTFPVQLDYPVDQANAATVQEAQSFKQSVEASLGKENVIVNVLETETSTHE
AQGFYAETPEQQDYDIISSWWGPDYQDPRTYLDIMSPVGGGSVIQKLGIKAGQNKDVVAAAGLDTYQTLLDEAAAITDDN
DARYKAYAKAQAYLTDSAVDIPVVALGGTPRVTKAVPFSGGFSWAGSKGPLAYKGMKLQDKPVTAKQYENAKEKWMKAKA
KSNAKYAEKLADHVEK

Nucleotide


Download         Length: 1971 bp        

>NTDB_id=1142872 DQN68_RS01365 WP_002992224.1 247427..249397(+) (amiA) [Streptococcus pyogenes strain NCTC8224]
ATGAAGAAAAGTAAATGGTTGGCAGCTGTAAGTGTTGCGATCTTGTCAGTATCCGCTTTGGCAGCTTGTGGTAATAAAAA
TGCTTCAGGTGGCTCAGAAGCTACAAAAACCTACAAGTACGTTTTTGTTAACGATCCAAAATCATTGGATTATATTTTGA
CTAATGGCGGTGGAACGACTGATGTGATAACACAAATGGTTGATGGTCTTTTGGAAAACGATGAGTATGGTAATTTAGTA
CCATCACTTGCTAAAGATTGGAAGGTTTCAAAAGACGGTCTGACTTATACTTATACTCTTCGCGATGGTGTCTCTTGGTA
TACGGCTGATGGTGAAGAATATGCCCCAGTAACAGCAGAAGATTTTGTGACTGGTTTGAAGCACGCGGTTGACGATAAAT
CAGATGCTCTTTACGTTGTTGAAGATTCAATAAAAAACTTAAAGGCTTACCAAAATGGTGAAGTAGATTTTAAAGAAGTT
GGTGTCAAAGCCCTTGACGATAAAACTGTTCAGTATACTTTGAACAAGCCTGAAAGCTACTGGAATTCAAAAACAACTTA
TAGTGTGCTTTTCCCAGTTAATGCGAAATTTTTGAAGTCAAAAGGTAAAGATTTTGGTACAACCGATCCATCATCAATCC
TTGTTAATGGTGCTTACTTCTTGAGCGCCTTCACCTCAAAATCATCTATGGAATTCCATAAAAATGAAAACTACTGGGAT
GCTAAGAATGTTGGGATAGAATCTGTTAAATTGACTTACTCAGATGGTTCAGACCCAGGTTCGTTCTACAAGAACTTTGA
CAAGGGTGAGTTCAGCGTTGCACGACTTTACCCAAATGACCCTACCTACAAATCAGCTAAGAAAAACTATGCTGATAACA
TTACTTACGGAATGTTGACTGGAGATATCCGTCATTTAACATGGAATTTGAACCGTACTTCTTTCAAAAACACTAAGAAA
GACCCTGCACAACAAGATGCCGGTAAGAAAGCTCTTAACAACAAGGATTTTCGTCAAGCTATTCAGTTTGCTTTTGACCG
AGCGTCATTCCAAGCACAAACTGCAGGTCAAGATGCCAAAACAAAAGCCTTACGTAACATGCTTGTGCCACCAACATTTG
TGACCATTGGAGAAAGTGATTTTGGTTCAGAAGTTGAAAAGGAAATGGCAAAACTTGGTGATGAATGGAAAGACGTTAAC
TTAGCTGATGCTCAAGATGGTTTCTATAATCCTGAAAAAGCAAAAGCTGAGTTTGCAAAAGCCAAAGAAGCTTTGACAGC
TGAAGGTGTAACCTTCCCAGTTCAATTAGATTACCCTGTTGACCAAGCAAACGCAGCAACTGTTCAGGAAGCTCAGTCTT
TCAAACAATCTGTTGAAGCATCTCTTGGTAAAGAAAATGTCATTGTCAATGTTCTTGAAACAGAAACATCAACTCACGAA
GCCCAAGGCTTCTATGCTGAGACCCCAGAACAACAAGACTACGATATCATTTCATCATGGTGGGGACCAGACTACCAAGA
TCCACGGACCTACCTTGACATCATGAGTCCAGTAGGTGGTGGATCTGTTATCCAAAAACTTGGAATCAAAGCAGGTCAAA
ATAAGGATGTTGTGGCAGCTGCAGGCCTTGATACTTACCAAACTCTCCTTGATGAAGCAGCAGCAATTACAGACGACAAC
GATGCGCGCTATAAAGCTTACGCAAAAGCACAAGCCTACCTTACAGATAGTGCCGTAGATATTCCAGTTGTGGCATTGGG
TGGCACTCCACGAGTTACTAAAGCCGTTCCATTTAGCGGGGGCTTCTCTTGGGCAGGGTCTAAAGGTCCTCTAGCATATA
AAGGAATGAAACTTCAAGACAAACCTGTCACAGCAAAACAATACGAAAATGCAAAAGAAAAATGGATGAAAGCAAAGGCT
AAGTCAAATGCAAAATATGCTGAGAAGTTAGCTGATCACGTTGAAAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(79-515)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5S4TJC7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

51.286

100

0.517
  amiA3 Streptococcus thermophilus LMG 18311

50

100

0.505
  amiA3 Streptococcus thermophilus LMD-9

49.698

100

0.502

Multiple sequence alignment