Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DQL17_RS03410 Genome accession   NZ_LS483496
Coordinates   668713..669405 (-) Length   230 a.a.
NCBI ID   WP_111688883.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC8455     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 663713..674405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL17_RS03380 (NCTC8455_00665) - 665588..665794 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  DQL17_RS03385 (NCTC8455_00666) - 665868..666074 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL17_RS03390 (NCTC8455_00667) - 666149..666355 (-) 207 WP_005648955.1 heavy-metal-associated domain-containing protein -
  DQL17_RS03395 (NCTC8455_00668) cueR 666432..666818 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQL17_RS03400 (NCTC8455_00669) metJ 666832..667149 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DQL17_RS03405 (NCTC8455_00670) rho 667397..668659 (+) 1263 WP_111688882.1 transcription termination factor Rho -
  DQL17_RS03410 (NCTC8455_00671) pilD 668713..669405 (-) 693 WP_111688883.1 prepilin peptidase Machinery gene
  DQL17_RS03415 (NCTC8455_00672) pilC 669402..670622 (-) 1221 WP_005691827.1 type II secretion system F family protein Machinery gene
  DQL17_RS03420 (NCTC8455_00673) pilB 670619..672013 (-) 1395 WP_005691826.1 GspE/PulE family protein Machinery gene
  DQL17_RS03425 (NCTC8455_00674) pilA 672010..672459 (-) 450 WP_005691824.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQL17_RS03430 (NCTC8455_00675) ampD 672574..673128 (+) 555 WP_005691822.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26742.76 Da        Isoelectric Point: 9.1329

>NTDB_id=1142725 DQL17_RS03410 WP_111688883.1 668713..669405(-) (pilD) [Haemophilus influenzae strain NCTC8455]
MIYFTMFLLGGILGIALWFYLSGFITRLQQEIYATYVELFPQNRSPFQPHFASIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWIGLTLIILWTISYLDWHYQLISTTPCLWLLTLGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKCYYR
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1142725 DQL17_RS03410 WP_111688883.1 668713..669405(-) (pilD) [Haemophilus influenzae strain NCTC8455]
ATGATTTATTTCACAATGTTTTTATTAGGCGGTATCTTAGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACACG
TTTGCAGCAAGAGATTTATGCGACTTACGTTGAATTATTTCCACAAAACCGTTCTCCATTTCAACCGCACTTTGCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGAGTTGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGATCGGACTCACACTTATTATTCTTTGGACAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACTCTAGGATTATTTGGAGCAGACAATAACTTTTCATTGCTAACGT
TATCTGAAAGCATAAAAAGTGCGGCTAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATGTTATTACAGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTGCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(92-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

97.391

100

0.974
  pilD Haemophilus influenzae Rd KW20

95.652

100

0.957

Multiple sequence alignment