Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilD   Type   Machinery gene
Locus tag   DQL18_RS04025 Genome accession   NZ_LS483486
Coordinates   765065..765757 (+) Length   230 a.a.
NCBI ID   WP_105905460.1    Uniprot ID   -
Organism   Haemophilus influenzae strain NCTC12194     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 760065..770757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL18_RS04005 (NCTC12194_00809) ampD 761336..761896 (-) 561 WP_011271974.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQL18_RS04010 (NCTC12194_00810) pilA 762011..762460 (+) 450 WP_011271973.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQL18_RS04015 (NCTC12194_00811) pilB 762457..763851 (+) 1395 WP_105905461.1 GspE/PulE family protein Machinery gene
  DQL18_RS04020 (NCTC12194_00812) pilC 763848..765068 (+) 1221 WP_042601844.1 type II secretion system F family protein Machinery gene
  DQL18_RS04025 (NCTC12194_00813) pilD 765065..765757 (+) 693 WP_105905460.1 prepilin peptidase Machinery gene
  DQL18_RS04030 (NCTC12194_00814) rho 765811..767073 (-) 1263 WP_005648966.1 transcription termination factor Rho -
  DQL18_RS04035 (NCTC12194_00815) metJ 767321..767638 (+) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  DQL18_RS04040 (NCTC12194_00816) cueR 767652..768038 (-) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  DQL18_RS04045 (NCTC12194_00817) - 768115..768321 (+) 207 WP_048941374.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04050 (NCTC12194_00818) - 768395..768601 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04055 (NCTC12194_00819) - 768675..768881 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04060 (NCTC12194_00820) - 768955..769161 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04065 (NCTC12194_00821) - 769235..769441 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04070 (NCTC12194_00822) - 769515..769721 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04075 (NCTC12194_00823) - 769807..770013 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  DQL18_RS04080 (NCTC12194_00824) - 770087..770293 (+) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26588.53 Da        Isoelectric Point: 8.8544

>NTDB_id=1142632 DQL18_RS04025 WP_105905460.1 765065..765757(+) (pilD) [Haemophilus influenzae strain NCTC12194]
MIYFTMFLLGGIFGIALWFYLSGFITRLQQEIYATYIELFPQNFLPFQSSVSSIQQKKCGHILRYFLSVGVGFIFLQIAF
KDSIFTVWLGATLLILWAISYLDWHYQLISTTPCLWLLTIGLFGADNNFSLLTLSESIKSAASFFIVFYAIYWIAKFYYG
KEAFGRGDYWLAMALGSFIHLETLPHFLLLASVLGICFSLIHKKKKEFIPFAPFMNLSAVIIYFVKYYGY

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1142632 DQL18_RS04025 WP_105905460.1 765065..765757(+) (pilD) [Haemophilus influenzae strain NCTC12194]
ATGATTTACTTCACAATGTTTTTATTAGGCGGCATCTTCGGGATCGCATTGTGGTTCTACCTATCTGGTTTTATTACCCG
TTTACAGCAAGAGATTTATGCGACTTATATTGAATTATTCCCACAAAACTTTCTGCCATTTCAGTCTAGCGTTTCCTCTA
TTCAACAAAAAAAGTGCGGTCATATTTTGAGGTATTTTTTAAGTGTTGGGGTAGGATTTATATTTTTACAAATTGCCTTC
AAAGATTCTATTTTTACTGTATGGCTAGGAGCCACACTTCTTATCCTTTGGGCAATCAGTTATCTTGATTGGCACTATCA
ACTTATTTCTACGACACCCTGTTTATGGTTACTTACAATCGGTTTATTTGGAGCAGACAATAATTTTTCATTGCTTACGT
TATCTGAAAGCATAAAAAGTGCGGCAAGTTTTTTTATTGTTTTCTACGCAATCTATTGGATTGCAAAATTCTATTACGGA
AAAGAAGCCTTTGGACGGGGAGATTATTGGCTAGCAATGGCATTAGGAAGTTTTATTCATTTAGAAACCTTACCGCACTT
TTTATTATTAGCCTCAGTTCTTGGAATATGTTTTTCGCTTATTCATAAAAAGAAAAAAGAATTTATACCTTTTGCCCCTT
TTATGAACTTATCAGCTGTCATCATTTATTTCGTCAAATATTACGGATATTAA

Domains

Predicted by InterproScan.

Type IV leader peptidase family (Peptidase_A24)

(93-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilD Haemophilus influenzae 86-028NP

91.304

100

0.913
  pilD Haemophilus influenzae Rd KW20

90.87

100

0.909

Multiple sequence alignment