Detailed information NTG1142606

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: DQL18_RS00045
• Genome accession: NZ_LS483486
• Coordinates: 14945..16066 (+)
• Length: 373 a.a.
• NCBI ID: WP_042593727.1
• Uniprot ID: -
• Organism: Haemophilus influenzae strain NCTC12194
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 9945..21066

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL18_RS00030 (NCTC12194_00006)	leuC	10099..11508 (-)	1410	WP_011272333.1	3-isopropylmalate dehydratase large subunit	-
DQL18_RS00035 (NCTC12194_00007)	leuB	11683..12759 (-)	1077	WP_105897944.1	3-isopropylmalate dehydrogenase	-
DQL18_RS00040 (NCTC12194_00008)	leuA	12841..14388 (-)	1548	WP_042594400.1	2-isopropylmalate synthase	-
DQL18_RS00045 (NCTC12194_00009)	dprA	14945..16066 (+)	1122	WP_042593727.1	DNA-processing protein DprA	Machinery gene
DQL18_RS00050 (NCTC12194_00010)	yaaA	16120..16896 (+)	777	WP_013527264.1	peroxide stress protein YaaA	-
DQL18_RS00055 (NCTC12194_00011)	-	16889..17470 (+)	582	WP_015701980.1	hypothetical protein	-
DQL18_RS00060 (NCTC12194_00013)	pfkA	17566..18532 (+)	967	Protein_11	6-phosphofructokinase	-
DQL18_RS00065 (NCTC12194_00014)	smpB	18773..19258 (+)	486	WP_005647965.1	SsrA-binding protein SmpB	-
DQL18_RS00070 (NCTC12194_00015)	fis	19353..19652 (-)	300	WP_005651583.1	DNA-binding transcriptional regulator Fis	-
DQL18_RS00075 (NCTC12194_00016)	dusB	19646..20626 (-)	981	WP_038440094.1	tRNA dihydrouridine synthase DusB	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41670.76 Da
• Isoelectric Point: 6.4124

>NTDB_id=1142606 DQL18_RS00045 WP_042593727.1 14945..16066(+) (dprA) [Haemophilus influenzae strain NCTC12194]
MNDITYTLLRLMQVPKLGGVGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALVWSQKEGNHLVNY
FSPFYPFLLKQTASFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENTKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=1142606 DQL18_RS00045 WP_042593727.1 14945..16066(+) (dprA) [Haemophilus influenzae strain NCTC12194]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTGCCTAAACTTGGCGGCGTTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGGTGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAGCCTGAAGCAAAATTTATTGAGCCTGCACTTGTGTGGTCACAAAAAGAGGGAAATCATTTAGTGAATTAT
TTTTCCCCTTTTTATCCCTTTTTGTTGAAACAGACCGCAAGTTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGAAGCCGTTATTGCACGACTTACGGAGAATATTGGGCAAAACATTTTGCGA
CAGAACTTTCATTAGCTGGCTTTACGATTACTAGTGGACTTGCATTAGGAATTGATGGACATTGCCATCAAGCTGTCGTC
AATATTCAAGGACAAACTATTGCGGTTTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCAGC
ACAAATCATCGAAAATAATGGCGCATTAGTCTCTGAGTTCTTACCAAACCAAGCCCCCATTGCCGCTAATTTCCCACGTC
GTAATCGGATTATTAGCGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACAGAAAAAAGCGGCTCGCTTATTACTGCG
CGATATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCGGGAAACATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTAATTAAACAAGGTGCAATGTTAGTAGAAAATACTAAAGATATTTTGGAAACCCTCTACCAACATTCTATCCATAGCC
AAACTGAAATCGATTTTGATCAGATCGCCGTGCCTAATTACACGCCACCACCTGATCCTCGCCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTATTCGCGTATTGGTTACACGCCTGTGAGCATTGATGATTTAGCAGAAGAATTTAATTTAAGCGT
CGATGTTTTGCTTGTTCAGTTGCTCGATCTTGAGTTGCAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCGTTT
AG

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (311-366)

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	99.464	100	0.995
dprA	Glaesserella parasuis strain SC1401	52.161	93.029	0.485
dprA	Vibrio campbellii strain DS40M4	43.883	100	0.442
dprA	Vibrio cholerae strain A1552	43.288	97.855	0.424
dprA	Legionella pneumophila strain ERS1305867	40.634	93.029	0.378