Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQN71_RS02550 Genome accession   NZ_LS483471
Coordinates   495157..496458 (+) Length   433 a.a.
NCBI ID   WP_041826810.1    Uniprot ID   -
Organism   Streptococcus cristatus strain NCTC13807     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 490157..501458
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN71_RS02525 (NCTC13807_00488) - 490936..491568 (+) 633 WP_015605263.1 response regulator transcription factor -
  DQN71_RS02530 (NCTC13807_00489) - 491606..493006 (+) 1401 WP_015605262.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQN71_RS02535 (NCTC13807_00490) - 493006..493368 (+) 363 WP_015605261.1 S1 RNA-binding domain-containing protein -
  DQN71_RS02540 (NCTC13807_00491) cysK 493419..494348 (-) 930 WP_015605260.1 cysteine synthase A -
  DQN71_RS02545 (NCTC13807_00492) - 494465..495100 (-) 636 WP_015605259.1 YigZ family protein -
  DQN71_RS02550 (NCTC13807_00493) comFA/cflA 495157..496458 (+) 1302 WP_041826810.1 DEAD/DEAH box helicase Machinery gene
  DQN71_RS02555 (NCTC13807_00494) comFC/cflB 496455..497120 (+) 666 WP_015605257.1 ComF family protein Machinery gene
  DQN71_RS02560 (NCTC13807_00495) hpf 497202..497744 (+) 543 WP_015605256.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQN71_RS02565 (NCTC13807_00496) - 497896..501018 (+) 3123 WP_015605255.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49917.70 Da        Isoelectric Point: 8.6806

>NTDB_id=1142304 DQN71_RS02550 WP_041826810.1 495157..496458(+) (comFA/cflA) [Streptococcus cristatus strain NCTC13807]
MLERKDCLGRIFTKDQLSPELRSQAQQMPSMREERRRLFCSRCGSQVDKENYQLPVNAYYCRECLILGRVRSDQELYYFP
QEDFPENQVLKWQGKLTAFQEKVSQGLLESVVQKQNSLVHAVTGAGKTEMIYQVIAEVVDRGGAVCLASPRIDVCLELYR
RLKLDFACPISLLHGESEPYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPVLYHAVDQSVKEEGTTIFLTATS
TDELDKKVQKGELKRLSLPRRFHGNPLIVPQKVWLADFQKYLAKKKLPPKLRKYIERQRKTGFPLLIFASEIKRGQEFAQ
VLEENFPAERVGFVASTTENRLEIVEEFRKREITILVTTTILERGVTFPCVDVFVLEAHHRLFSRSALVQISGRVGRSMD
RPTGDLFFFHDGTTRSIEKAIREIKLMNKEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1142304 DQN71_RS02550 WP_041826810.1 495157..496458(+) (comFA/cflA) [Streptococcus cristatus strain NCTC13807]
ATGTTAGAAAGAAAAGATTGTTTAGGTAGGATATTTACAAAGGATCAGCTAAGTCCTGAGCTGCGCTCGCAGGCCCAGCA
GATGCCCAGTATGCGAGAGGAAAGGCGGAGATTGTTTTGCAGCCGCTGTGGCTCTCAAGTGGACAAGGAGAACTACCAAC
TACCTGTCAACGCCTATTATTGCAGGGAATGTCTGATATTGGGGCGAGTTCGGAGTGATCAAGAACTTTATTATTTTCCG
CAGGAAGACTTTCCAGAAAATCAGGTACTCAAGTGGCAGGGGAAATTGACAGCCTTTCAAGAGAAAGTTTCTCAGGGACT
GTTAGAGTCAGTCGTTCAAAAGCAGAATAGCTTGGTTCATGCGGTGACTGGGGCAGGCAAAACGGAGATGATTTATCAGG
TGATTGCAGAGGTGGTTGATCGCGGAGGTGCCGTTTGCCTGGCCAGCCCGCGGATTGATGTCTGTTTGGAGCTTTATCGT
CGCCTTAAGCTAGATTTTGCTTGCCCGATTTCGCTTTTGCATGGCGAATCCGAGCCCTATTTTCGCAGTCCCTTGGTCAT
CGCCACCACCCATCAGCTTCTTAAATTTTATCGAGCCTTTGATTTGCTGATTGTGGACGAGGTGGATGCCTTTCCTTATG
TGGACAATCCCGTGCTCTACCATGCCGTAGATCAGTCGGTCAAGGAGGAGGGAACGACAATTTTCTTAACTGCCACTTCG
ACGGATGAGTTGGATAAAAAAGTCCAAAAAGGAGAATTAAAACGACTCAGCCTTCCTCGCCGCTTCCATGGCAATCCTTT
GATTGTGCCCCAAAAAGTTTGGCTGGCAGATTTTCAAAAATATCTAGCGAAAAAGAAATTGCCACCTAAACTGAGAAAAT
ATATCGAGAGACAGAGAAAAACAGGCTTTCCTTTGCTGATCTTTGCCTCAGAAATCAAGAGAGGTCAAGAATTTGCGCAA
GTTTTAGAGGAGAATTTTCCAGCGGAAAGAGTCGGTTTTGTAGCTTCAACAACTGAAAATCGTTTAGAAATCGTTGAAGA
GTTTCGCAAGCGAGAAATTACCATTTTGGTCACGACGACCATCTTAGAGCGTGGTGTGACCTTTCCCTGTGTAGATGTCT
TTGTTCTGGAGGCCCACCATCGTCTCTTTAGCCGTAGCGCCTTGGTGCAAATTTCTGGACGGGTGGGACGTAGTATGGAT
AGACCGACGGGAGATTTATTCTTCTTTCACGACGGCACTACACGTTCAATCGAAAAAGCGATTCGTGAAATCAAACTGAT
GAACAAGGAGGCTGGCCTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(297-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

71.831

98.383

0.707
  comFA/cflA Streptococcus pneumoniae D39

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae R6

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae TIGR4

71.028

98.845

0.702
  comFA/cflA Streptococcus pneumoniae Rx1

71.028

98.845

0.702
  comFA/cflA Streptococcus mitis SK321

70.892

98.383

0.697
  comFA Lactococcus lactis subsp. cremoris KW2

54.68

93.764

0.513
  comFA Latilactobacillus sakei subsp. sakei 23K

41.628

99.307

0.413
  comFA Bacillus subtilis subsp. subtilis str. 168

39.659

94.919

0.376

Multiple sequence alignment