Detailed information NTG1142209

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: DQN30_RS09320
• Genome accession: NZ_LS483458
• Coordinates: 1918187..1918864 (+)
• Length: 225 a.a.
• NCBI ID: WP_005633332.1
• Uniprot ID: -
• Organism: Haemophilus haemolyticus strain NCTC10839
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1913187..1923864

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN30_RS09280 (NCTC10839_01857)	mutM	1913216..1914031 (-)	816	WP_111697091.1	DNA-formamidopyrimidine glycosylase	-
DQN30_RS09285 (NCTC10839_01858)	rpmG	1914103..1914273 (-)	171	WP_005613503.1	50S ribosomal protein L33	-
DQN30_RS09290 (NCTC10839_01859)	rpmB	1914285..1914521 (-)	237	WP_005542826.1	50S ribosomal protein L28	-
DQN30_RS09295 (NCTC10839_01860)	radC	1914735..1915400 (-)	666	WP_111697092.1	DNA repair protein RadC	-
DQN30_RS09300 (NCTC10839_01861)	coaBC	1915564..1916766 (+)	1203	WP_111697093.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
DQN30_RS09305 (NCTC10839_01862)	dut	1916814..1917269 (+)	456	WP_005631431.1	dUTP diphosphatase	-
DQN30_RS09310 (NCTC10839_01863)	slmA	1917273..1917929 (+)	657	WP_048954244.1	nucleoid occlusion factor SlmA	-
DQN30_RS09315 (NCTC10839_01864)	-	1917951..1918202 (+)	252	WP_005631427.1	YheU family protein	-
DQN30_RS09320 (NCTC10839_01865)	crp	1918187..1918864 (+)	678	WP_005633332.1	cAMP-activated global transcriptional regulator CRP	Regulator
DQN30_RS09325 (NCTC10839_01866)	rlmC	1919228..1920406 (-)	1179	WP_111697094.1	23S rRNA (uracil(747)-C(5))-methyltransferase RlmC	-
DQN30_RS09330 (NCTC10839_01867)	nagZ	1920418..1921455 (-)	1038	WP_111697095.1	beta-N-acetylhexosaminidase	-
DQN30_RS09335 (NCTC10839_01868)	-	1921459..1921809 (-)	351	WP_111697096.1	YcfL family protein	-
DQN30_RS09340 (NCTC10839_01869)	hinT	1921809..1922159 (-)	351	WP_032803248.1	purine nucleoside phosphoramidase	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25266.94 Da
• Isoelectric Point: 6.6051

>NTDB_id=1142209 DQN30_RS09320 WP_005633332.1 1918187..1918864(+) (crp) [Haemophilus haemolyticus strain NCTC10839]
MSNELTEIDEVVTSSQEEETTQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSAKDDEGKEMILTYL
GAGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVSNLAFLDVAGRIA
QTLMNLAKQPDAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide

• Length: 678 bp

>NTDB_id=1142209 DQN30_RS09320 WP_005633332.1 1918187..1918864(+) (crp) [Haemophilus haemolyticus strain NCTC10839]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTCACCTCCTCTCAAGAAGAAGAGACAACTCAACGAGATCCAGTTTT
AGATTGGTTTCTTACTCACTGCCATTTACATAAATATCCCGCAAAATCGACTTTAATTCACGCAGGTGAAGATGCAACGA
CACTTTATTATGTCATTAAAGGCTCTGTAATGGTGTCAGCAAAAGATGACGAAGGTAAAGAGATGATTCTCACTTATTTG
GGAGCTGGACAATTCTTTGGTGAGGCTGGATTATTTGATGAGGGTTCAAAACGCTCTGCTTGGGTAAAAACAAAAACAAC
ATGTGAAATTGCTGAGATTTCTTATAAAAAATATCGTCAATTAATTCAAGCAAACCCAGAAATCTTAATGTTTTTAACCG
CACAATTGGCAAGACGTTTACAAAATACTTCACGCCAAGTCAGTAATTTAGCATTCTTAGATGTGGCAGGTCGTATTGCT
CAAACGCTAATGAACTTAGCTAAACAGCCTGACGCAATGACACATCCTGATGGGATGCAAATCAAAATTACACGTCAAGA
AATAGGGCAAATGGTTGGTTGTTCACGAGAAACTGTAGGACGTATTATTAAGATGTTAGAGGATCAGAATCTTATCCATG
CTCATGGAAAAACCATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

• Cyclic nucleotide-binding domain (cNMP_binding) (37-125)

• Crp-like helix-turn-helix domain (HTH_Crp_2) (157-221)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Haemophilus influenzae Rd KW20	97.778	100	0.978
crp	Vibrio cholerae strain A1552	75.98	90.667	0.689
crp	Acinetobacter baumannii D1279779	47.668	85.778	0.409