Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DQL01_RS09205 Genome accession   NZ_LS483451
Coordinates   1731790..1732449 (+) Length   219 a.a.
NCBI ID   WP_111702693.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4041STDY6836166     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1726790..1737449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL01_RS09180 - 1727086..1727403 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  DQL01_RS09185 - 1727418..1728314 (-) 897 WP_061368565.1 hypothetical protein -
  DQL01_RS09190 - 1728317..1729579 (-) 1263 WP_111702691.1 PTS sugar transporter subunit IIC -
  DQL01_RS09195 - 1729859..1731037 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  DQL01_RS09200 - 1731265..1731720 (-) 456 WP_111702692.1 GNAT family N-acetyltransferase -
  DQL01_RS09205 cclA/cilC 1731790..1732449 (+) 660 WP_111702693.1 prepilin peptidase Machinery gene
  DQL01_RS09210 - 1732501..1733652 (-) 1152 WP_000481750.1 helix-turn-helix domain-containing protein -
  DQL01_RS09215 - 1733667..1734398 (-) 732 Protein_1765 hypothetical protein -
  DQL01_RS09220 - 1734618..1734728 (+) 111 Protein_1766 prepilin peptidase -
  DQL01_RS09225 trpA 1734700..1735476 (-) 777 WP_001126994.1 tryptophan synthase subunit alpha -
  DQL01_RS09230 trpB 1735469..1736692 (-) 1224 WP_061368563.1 tryptophan synthase subunit beta -
  DQL01_RS09235 - 1736670..1737269 (-) 600 WP_061368562.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24881.00 Da        Isoelectric Point: 7.9675

>NTDB_id=1142072 DQL01_RS09205 WP_111702693.1 1731790..1732449(+) (cclA/cilC) [Streptococcus pneumoniae strain 4041STDY6836166]
MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNHFRCRYCKVRYPVWYALFELGLG
LLFLLYSWGWLSLGQVVLITAGLTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFMDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1142072 DQL01_RS09205 WP_111702693.1 1731790..1732449(+) (cclA/cilC) [Streptococcus pneumoniae strain 4041STDY6836166]
ATGATTGATATTTATTTTTTTCTTGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTATCGC
AGGTTTTTAATCATTTTCGCTGTCGCTACTGCAAGGTCCGCTATCCAGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGGATGGCTCTCCTTGGGACAAGTCGTCCTAATCACCGCTGGTTTGACCTTGAGCAT
CTATGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATGGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-88)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

95.89

100

0.959
  cclA/cilC Streptococcus pneumoniae Rx1

95.434

100

0.954
  cclA/cilC Streptococcus pneumoniae D39

95.434

100

0.954
  cclA/cilC Streptococcus pneumoniae R6

95.434

100

0.954
  cclA/cilC Streptococcus mitis SK321

94.064

100

0.941
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment