Detailed information NTG1141976

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DQL12_RS04880
• Genome accession: NZ_LS483450
• Coordinates: 903281..904234 (+)
• Length: 317 a.a.
• NCBI ID: WP_050255615.1
• Uniprot ID: A0A4J2AUQ0
• Organism: Streptococcus pneumoniae strain 4041STDY6583227
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 898281..909234

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL12_RS04855	rpmG	899024..899173 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
DQL12_RS04860	secG	899213..899446 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
DQL12_RS04865	rnr	899548..901902 (+)	2355	WP_000654917.1	ribonuclease R	-
DQL12_RS04870	smpB	901865..902332 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
DQL12_RS04875	tehB	902348..903208 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
DQL12_RS04880	coiA	903281..904234 (+)	954	WP_050255615.1	competence protein CoiA	Machinery gene
DQL12_RS04885	pepF	904253..906055 (+)	1803	WP_001864211.1	oligoendopeptidase F	Regulator
DQL12_RS04890	-	906057..906770 (+)	714	WP_000230399.1	O-methyltransferase	-
DQL12_RS04895	prsA	906837..907778 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
DQL12_RS04900	-	907897..908238 (-)	342	Protein_915	transposase	-
DQL12_RS04910	-	908651..908746 (+)	96	Protein_916	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38306.92 Da
• Isoelectric Point: 8.9860

>NTDB_id=1141976 DQL12_RS04880 WP_050255615.1 903281..904234(+) (coiA) [Streptococcus pneumoniae strain 4041STDY6583227]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQIHLRQGPSVRTHFAHKSLKDCDFFFENESPEHIANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQDFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYRNFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1141976 DQL12_RS04880 WP_050255615.1 903281..904234(+) (coiA) [Streptococcus pneumoniae strain 4041STDY6583227]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGATCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACATAGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGATTTTCTGTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATTCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCGGAACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-262)

3D structure

• AlphaFold DB: A0A4J2AUQ0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	98.423	100	0.984
coiA	Streptococcus pneumoniae Rx1	97.792	100	0.978
coiA	Streptococcus pneumoniae D39	97.792	100	0.978
coiA	Streptococcus pneumoniae R6	97.792	100	0.978
coiA	Streptococcus mitis NCTC 12261	88.328	100	0.883
coiA	Lactococcus lactis subsp. cremoris KW2	42.284	100	0.432