Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   DQK98_RS08785 Genome accession   NZ_LS483449
Coordinates   1675996..1676655 (+) Length   219 a.a.
NCBI ID   WP_000565001.1    Uniprot ID   A0A0B7M7B9
Organism   Streptococcus pneumoniae strain 4041STDY6836170     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1670996..1681655
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQK98_RS08760 - 1671301..1671618 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  DQK98_RS08765 - 1671633..1672529 (-) 897 WP_000825669.1 PEP phosphonomutase -
  DQK98_RS08770 - 1672532..1673794 (-) 1263 WP_111688159.1 PTS sugar transporter subunit IIC -
  DQK98_RS08775 - 1674074..1675252 (+) 1179 WP_000175876.1 ROK family transcriptional regulator -
  DQK98_RS08780 - 1675480..1675926 (-) 447 WP_111688160.1 GNAT family N-acetyltransferase -
  DQK98_RS08785 cclA/cilC 1675996..1676655 (+) 660 WP_000565001.1 prepilin peptidase Machinery gene
  DQK98_RS08790 - 1676707..1677858 (-) 1152 WP_050259352.1 XRE family transcriptional regulator -
  DQK98_RS08795 - 1677873..1678604 (-) 732 WP_000934017.1 hypothetical protein -
  DQK98_RS08800 - 1678824..1678934 (+) 111 Protein_1662 prepilin peptidase -
  DQK98_RS08805 trpA 1678906..1679682 (-) 777 WP_111688161.1 tryptophan synthase subunit alpha -
  DQK98_RS08810 trpB 1679675..1680898 (-) 1224 WP_000331289.1 tryptophan synthase subunit beta -
  DQK98_RS08815 - 1680876..1681475 (-) 600 WP_000169904.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24820.92 Da        Isoelectric Point: 7.2761

>NTDB_id=1141914 DQK98_RS08785 WP_000565001.1 1675996..1676655(+) (cclA/cilC) [Streptococcus pneumoniae strain 4041STDY6836170]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=1141914 DQK98_RS08785 WP_000565001.1 1675996..1676655(+) (cclA/cilC) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTAGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATTGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M7B9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

98.174

100

0.982
  cclA/cilC Streptococcus pneumoniae Rx1

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae D39

96.804

100

0.968
  cclA/cilC Streptococcus pneumoniae R6

96.804

100

0.968
  cclA/cilC Streptococcus mitis SK321

92.237

100

0.922
  cclA/cilC Streptococcus mitis NCTC 12261

87.215

100

0.872

Multiple sequence alignment