Detailed information NTG1141898

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DQK98_RS04850
• Genome accession: NZ_LS483449
• Coordinates: 916979..917932 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain 4041STDY6836170
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 911979..922932

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK98_RS04825	rpmG	912722..912871 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
DQK98_RS04830	secG	912911..913144 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
DQK98_RS04835	rnr	913246..915600 (+)	2355	WP_050206133.1	ribonuclease R	-
DQK98_RS04840	smpB	915563..916030 (+)	468	WP_001051747.1	SsrA-binding protein SmpB	-
DQK98_RS04845	tehB	916046..916906 (+)	861	WP_000413763.1	SAM-dependent methyltransferase TehB	-
DQK98_RS04850	coiA	916979..917932 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
DQK98_RS04855	pepF	917951..919753 (+)	1803	WP_111688086.1	oligoendopeptidase F	Regulator
DQK98_RS04860	-	919755..920468 (+)	714	WP_000230399.1	O-methyltransferase	-
DQK98_RS04865	prsA	920535..921476 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
DQK98_RS04870	-	921595..921936 (-)	342	Protein_927	transposase	-
DQK98_RS04880	-	922348..922443 (+)	96	Protein_928	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=1141898 DQK98_RS04850 WP_000495909.1 916979..917932(+) (coiA) [Streptococcus pneumoniae strain 4041STDY6836170]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1141898 DQK98_RS04850 WP_000495909.1 916979..917932(+) (coiA) [Streptococcus pneumoniae strain 4041STDY6836170]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435