Detailed information NTG1141863

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: DQK99_RS10825
• Genome accession: NZ_LS483448
• Coordinates: 1961839..1962546 (+)
• Length: 235 a.a.
• NCBI ID: WP_000166475.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 4041STDY6836167
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1960726..1961115	1961839..1962546	flank	724

Gene organization within MGE regions

Location: 1960726..1962546

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQK99_RS10810	-	1960726..1961283 (-)	558	Protein_2005	transposase	-
DQK99_RS12380	-	1961269..1961755 (+)	487	Protein_2006	cupin domain-containing protein	-
DQK99_RS10825	vicR	1961839..1962546 (+)	708	WP_000166475.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27230.61 Da
• Isoelectric Point: 6.6568

>NTDB_id=1141863 DQK99_RS10825 WP_000166475.1 1961839..1962546(+) (vicR) [Streptococcus pneumoniae strain 4041STDY6836167]
MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAETEPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKAPQFIRTIRGYGYKFKEL

Nucleotide

• Length: 708 bp

>NTDB_id=1141863 DQK99_RS10825 WP_000166475.1 1961839..1962546(+) (vicR) [Streptococcus pneumoniae strain 4041STDY6836167]
ATGACAAAACAAGTCTTATTAGTGGATGATGAAGAACACATTCTGAAATTGCTTGACTACCATTTAAGTAAGGAAGGCTT
TTCTACTCAATTGGTAACAAATGGACGGAAGGCCTTAGCTTTGGCAGAAACAGAACCCTTTGATTTTATCTTGCTTGATA
TCATGTTACCACAATTAGATGGCATGGAAGTTTGTAAGCGGCTGAGAGCCAAAGGCGTCAAAACTCCAATTATGATGGTT
TCTGCGAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGGGCTGATGACTACCTGACCAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTGTCCTCAGGCGAACTAAAGGAGAACAAGAAGGAGATGATTCAGATAATATCG
CTGACGATTCTTGGCTATTTGGGACCTTGAAAGTATACCCTGAGCGTCATGAAGTCTACAAGGCGAATAAGTTACTGAGT
TTGACCCCAAAAGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACACTGACTAGAGAGCGTCTTTTGGA
ACGTATCTGGGGGTATGACTTTGGGCAGGAAACACGTTTGGTGGACGTTCATATTGGTAAGTTAAGGGAAAAAATTGAAG
ACAATCCTAAAGCCCCTCAATTTATTCGAACCATTCGGGGGTATGGTTATAAGTTCAAGGAGTTATAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (159-232)

• Response regulator receiver domain (Response_reg) (5-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	48.707	98.723	0.481
micA	Streptococcus pneumoniae Cp1015	47.845	98.723	0.472
covR	Lactococcus lactis subsp. lactis strain DGCC12653	40.773	99.149	0.404
covR	Streptococcus salivarius strain HSISS4	39.744	99.574	0.396