Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQL20_RS04190 Genome accession   NZ_LS483444
Coordinates   777869..779242 (+) Length   457 a.a.
NCBI ID   WP_006596562.1    Uniprot ID   -
Organism   Streptococcus australis strain NCTC13166     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 772869..784242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL20_RS04170 (NCTC11371_00822) - 773146..775689 (+) 2544 WP_006597322.1 M1 family metallopeptidase -
  DQL20_RS04175 (NCTC11371_00823) - 775744..776286 (-) 543 WP_006597327.1 biotin transporter BioY -
  DQL20_RS04180 (NCTC11371_00824) - 776495..777091 (+) 597 WP_006596564.1 hypothetical protein -
  DQL20_RS04185 (NCTC11371_00825) ciaR 777205..777879 (+) 675 WP_006596563.1 response regulator transcription factor Regulator
  DQL20_RS04190 (NCTC11371_00826) ciaH 777869..779242 (+) 1374 WP_006596562.1 cell wall metabolism sensor histidine kinase WalK Regulator
  DQL20_RS04200 (NCTC11371_00827) - 779493..779879 (+) 387 WP_006596561.1 VOC family protein -
  DQL20_RS04205 (NCTC11371_00828) - 780075..781460 (+) 1386 WP_006596560.1 polysaccharide deacetylase family protein -
  DQL20_RS04210 (NCTC11371_00829) - 781769..782857 (-) 1089 WP_006596559.1 DEAD/DEAH box helicase -
  DQL20_RS04215 (NCTC11371_00830) - 782859..783836 (-) 978 WP_006596558.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 457 a.a.        Molecular weight: 52455.82 Da        Isoelectric Point: 6.8843

>NTDB_id=1141746 DQL20_RS04190 WP_006596562.1 777869..779242(+) (ciaH) [Streptococcus australis strain NCTC13166]
MLNKIKKTVNADDFSYFIRYFGLFTLIFSTMTLIIIQVMRSSLYTTVDENLKMLSKDRYSIISLANRTGNGMGRDEPDDD
RPEDDELGPENGPRPSVTSNSTAILLNDNFENITTDNGFLDLKTVTFSRGYLNKIKQIQITNHYKQKESYRAYLVDIDPD
DYIDGVKYAVIMTNISQLEQTSEKHESQIALVMICFWGISLFASIFLAKMSVKPLLESMNRQKAFVENASHELRTPLAVL
QNRLETLFRKPEATIMESSENIASSLDEVRNMRLLTTNLLNLARRDDGIKPEFCEIPPSFFDQTFANYEIIAEENDKIFE
YENHVERSLVSDKVLLKQLMTILYDNALKYTEEEGKIRFVAQFKDRYLYLRVEDNGPGIADEDKKRIFDRFYRVDKARTR
QKGGFGLGLSLAKQIVEAFNGTITVRDNKPKGAIFEVKLATKSDSKKKSSSKSTKNK

Nucleotide


Download         Length: 1374 bp        

>NTDB_id=1141746 DQL20_RS04190 WP_006596562.1 777869..779242(+) (ciaH) [Streptococcus australis strain NCTC13166]
ATGCTCAATAAAATTAAAAAAACTGTTAATGCGGATGACTTTTCTTATTTCATCCGCTATTTCGGACTCTTTACCTTAAT
TTTCTCAACCATGACCTTGATTATTATTCAAGTGATGCGGTCAAGTCTTTATACAACGGTTGATGAAAATTTAAAGATGC
TGAGTAAAGATCGTTATTCTATTATTAGCTTGGCCAATCGTACAGGAAATGGGATGGGAAGAGACGAACCAGATGATGAC
CGACCAGAAGATGATGAACTTGGTCCCGAGAATGGCCCTAGACCATCGGTCACTTCTAATAGTACAGCCATCCTCTTAAA
TGATAATTTTGAAAATATAACGACGGATAATGGTTTCCTGGATCTAAAAACAGTGACCTTTAGTCGCGGTTATTTAAATA
AGATCAAGCAGATTCAAATCACCAACCATTATAAGCAGAAGGAAAGTTACCGAGCTTATTTGGTAGATATTGATCCCGAT
GATTATATCGACGGGGTGAAATATGCCGTGATCATGACCAACATCAGCCAGTTGGAGCAGACTAGTGAAAAACATGAGAG
CCAAATCGCCTTGGTCATGATTTGCTTCTGGGGCATTTCTCTCTTTGCAAGTATCTTTCTGGCTAAGATGAGTGTGAAAC
CTCTCTTAGAGAGCATGAATCGGCAGAAGGCTTTTGTTGAAAATGCTTCTCATGAATTGCGGACACCTTTAGCCGTTTTG
CAAAATCGTTTGGAAACCCTGTTCCGAAAACCAGAGGCAACGATCATGGAATCCAGTGAGAACATCGCCTCCTCTTTGGA
TGAGGTTCGCAATATGCGCTTACTGACGACCAATCTCTTAAACTTAGCCCGCCGAGATGATGGGATTAAACCTGAGTTTT
GTGAAATCCCTCCCTCTTTTTTCGATCAAACCTTTGCCAATTATGAAATCATTGCCGAGGAAAATGATAAAATCTTCGAG
TATGAGAATCATGTCGAAAGGAGTCTGGTGTCTGACAAGGTCCTACTGAAACAGCTGATGACCATTTTGTATGACAATGC
CCTCAAATACACAGAGGAAGAAGGAAAGATACGATTTGTCGCCCAATTCAAGGATCGTTATCTCTATCTTAGGGTAGAGG
ATAATGGACCAGGGATTGCAGACGAAGATAAAAAACGGATTTTTGATCGATTCTACCGAGTGGATAAGGCGCGGACCCGT
CAAAAGGGTGGTTTTGGGTTAGGTCTTTCTTTAGCCAAGCAAATCGTAGAAGCTTTTAATGGTACCATTACTGTTCGAGA
TAACAAGCCTAAAGGTGCTATTTTTGAGGTAAAGCTAGCAACTAAATCAGATAGTAAAAAGAAATCCAGTTCTAAATCAA
CGAAGAACAAGTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(223-288)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(332-439)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae D39

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae R6

60.802

98.249

0.597
  ciaH Streptococcus pneumoniae TIGR4

60.802

98.249

0.597
  ciaH Streptococcus mutans UA159

50.797

96.061

0.488

Multiple sequence alignment