Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB10   Type   Machinery gene
Locus tag   HPOKI128_RS05955 Genome accession   NZ_CP006822
Coordinates   1246794..1247930 (+) Length   378 a.a.
NCBI ID   WP_025223377.1    Uniprot ID   -
Organism   Helicobacter pylori oki128     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1241794..1252930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPOKI128_RS05920 (HPOKI128_06125) panD 1242258..1242608 (+) 351 WP_025288488.1 aspartate 1-decarboxylase -
  HPOKI128_RS05925 (HPOKI128_06130) - 1242619..1242912 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  HPOKI128_RS05930 (HPOKI128_06135) - 1242912..1243907 (+) 996 WP_025288489.1 PDZ domain-containing protein -
  HPOKI128_RS05935 (HPOKI128_06140) comB6 1243915..1244970 (+) 1056 WP_025223380.1 P-type conjugative transfer protein TrbL Machinery gene
  HPOKI128_RS05940 (HPOKI128_06145) comB7 1244986..1245099 (+) 114 WP_001217868.1 hypothetical protein Machinery gene
  HPOKI128_RS05945 (HPOKI128_06150) comB8 1245096..1245839 (+) 744 WP_025223379.1 type IV secretion system protein Machinery gene
  HPOKI128_RS05950 (HPOKI128_06155) comB9 1245839..1246801 (+) 963 WP_025223378.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPOKI128_RS05955 (HPOKI128_06160) comB10 1246794..1247930 (+) 1137 WP_025223377.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPOKI128_RS05960 (HPOKI128_06165) - 1248000..1249412 (+) 1413 WP_025288490.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPOKI128_RS05965 (HPOKI128_06170) gmd 1249426..1250571 (+) 1146 WP_025288491.1 GDP-mannose 4,6-dehydratase -
  HPOKI128_RS05970 (HPOKI128_06175) - 1250564..1251496 (+) 933 WP_025288492.1 GDP-L-fucose synthase family protein -
  HPOKI128_RS05975 (HPOKI128_06185) hypE 1251753..1252751 (-) 999 WP_025288493.1 hydrogenase expression/formation protein HypE -

Sequence

Protein


Download         Length: 378 a.a.        Molecular weight: 41956.49 Da        Isoelectric Point: 9.9926

>NTDB_id=114171 HPOKI128_RS05955 WP_025223377.1 1246794..1247930(+) (comB10) [Helicobacter pylori oki128]
MNKWLKGALVFVGGFATIVTISLIYHQKPKAPLNNQPNLLNDDEVKYPLQDYTFTQNPQPTNTESSKDATIKALQEQLKA
ALKALNSQGMNSSKEETFKSSPIDPKTNTTPPKKDFSLKQLDLLAARITPFKQSPKNYEENLIFPMDNPKGIDGFTNLKE
KDIATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFAHMGKAVLIPKGSKVIGYYSNNNKMGEYRLDIVWS
RIITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGVPLLLSTLTNGLLIGITSALNNRGNKEGATNFFGDYLLMQL
MRQSGMGINQVVNQILRDKSKIAPIVVIREGSRVFISPNTDIFFPIPKENEVIAESLK

Nucleotide


Download         Length: 1137 bp        

>NTDB_id=114171 HPOKI128_RS05955 WP_025223377.1 1246794..1247930(+) (comB10) [Helicobacter pylori oki128]
ATGAATAAGTGGCTTAAGGGGGCGCTTGTTTTTGTAGGGGGTTTTGCAACGATTGTAACAATTTCTTTAATCTATCATCA
AAAGCCAAAAGCCCCCCTAAATAACCAACCCAACCTTTTGAATGACGATGAGGTGAAATACCCCCTACAAGACTACACCT
TCACTCAAAACCCACAGCCAACTAACACAGAAAGCTCCAAAGACGCTACCATCAAAGCCTTACAAGAACAGCTAAAAGCC
GCTTTAAAAGCCCTAAACTCCCAAGGAATGAACTCTTCTAAAGAAGAAACTTTTAAGAGCTCTCCCATAGATCCAAAAAC
AAACACAACCCCTCCTAAAAAAGACTTTTCTCTAAAGCAATTAGATTTACTGGCCGCTCGCATCACTCCCTTTAAACAAA
GCCCTAAAAATTACGAAGAAAACCTGATTTTCCCCATGGATAACCCTAAGGGCATTGATGGTTTTACCAACCTTAAAGAA
AAAGACATCGCCACCAATGAAAACAAGCTTTTACGCACCATTACAGCCGATAAAATGATACCCGCCTTTTTGATCACGCC
TATTTCTAGCCAGATCGCTGGTAAAGTCATCGCGCAAGTGGAGAGCGATATTTTTGCTCACATGGGCAAGGCCGTCTTAA
TCCCCAAAGGCTCTAAAGTCATAGGCTATTACAGCAACAATAACAAAATGGGCGAATACCGCTTGGATATTGTATGGAGC
CGCATCATCACTCCCCATGGCATCAATATCATGCTCACTAACGCTAAAGGGGCAGACATTAAAGGCTATAACGGCTTAGT
GGGGGAATTGATTGAAAGGAATTTCCAGCGCTATGGCGTGCCGTTACTGCTTTCTACGCTCACTAACGGCTTATTGATTG
GGATCACTTCGGCTTTAAACAACAGGGGCAATAAAGAAGGAGCCACCAATTTCTTTGGGGATTATCTTTTAATGCAATTG
ATGAGGCAAAGCGGCATGGGGATCAATCAAGTGGTCAATCAAATTTTAAGAGATAAGAGCAAAATCGCTCCTATTGTGGT
GATTAGAGAGGGGAGTAGGGTCTTCATTTCGCCCAATACTGACATCTTCTTTCCTATACCCAAAGAGAATGAAGTCATCG
CTGAGTCTTTGAAGTAA

Domains

Predicted by InterproScan.

Bacterial conjugation TrbI-like protein (TrbI)

(173-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB10 Helicobacter pylori P1

96.032

100

0.96

Multiple sequence alignment