Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQN42_RS02275 Genome accession   NZ_LS483436
Coordinates   449691..450992 (+) Length   433 a.a.
NCBI ID   WP_003078363.1    Uniprot ID   -
Organism   Streptococcus intermedius strain NCTC11324     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 444691..455992
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN42_RS02260 (NCTC11324_00459) - 444960..447611 (+) 2652 WP_003078269.1 valine--tRNA ligase -
  DQN42_RS02265 (NCTC11324_00460) cysK 447971..448900 (-) 930 WP_004234070.1 cysteine synthase A -
  DQN42_RS02270 (NCTC11324_00461) - 448999..449634 (-) 636 WP_003073631.1 YigZ family protein -
  DQN42_RS02275 (NCTC11324_00462) comFA/cflA 449691..450992 (+) 1302 WP_003078363.1 DEAD/DEAH box helicase Machinery gene
  DQN42_RS02280 (NCTC11324_00463) - 450989..451654 (+) 666 WP_003078227.1 ComF family protein -
  DQN42_RS02285 (NCTC11324_00464) hpf 451733..452275 (+) 543 WP_003073626.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQN42_RS02290 (NCTC11324_00465) rsmD 452474..453013 (+) 540 WP_003078233.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DQN42_RS02295 (NCTC11324_00466) coaD 453003..453500 (+) 498 WP_003078294.1 pantetheine-phosphate adenylyltransferase -
  DQN42_RS02300 (NCTC11324_00467) sepM 453481..454536 (+) 1056 WP_003078259.1 SepM family pheromone-processing serine protease Regulator
  DQN42_RS02305 (NCTC11324_00468) - 454817..455380 (+) 564 WP_004234076.1 YutD family protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49258.96 Da        Isoelectric Point: 8.9325

>NTDB_id=1141428 DQN42_RS02275 WP_003078363.1 449691..450992(+) (comFA/cflA) [Streptococcus intermedius strain NCTC11324]
MIELQDYLGRIFTRSQLPLGLQQQAQTLSGMIEKKGKLWCNRCGQVVNKEKQQLPIGAYYCRSCVRLGRVRSDEKLYYFP
QAEFPKTNVLTWEGRLTDYQAKVSQGLVEAVAKQKNSLVHAVTGAGKTEMIYQVVAQVINEGGAVCLASPRIDVCLELHR
RLQEDFSCDIALLHGESEVYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPMLYHAVTQSVKEQSTIIFLTATS
TDELDKKVSKGELNRLSLPRRFHGNPLIVPKKVWLENFQKYLNQKKLVPKLEQFVKKQRKTGFPLLIFASEIKRGQELAE
VLQSYFSSENVGFVASTTENRLDIVEKFRQKEITILVTTTILERGVTFPCVDVFVVEANHRLFSRSALVQIAGRVGRSMD
RPTGELLFFHDGTNFAIERAIQEIKAMNQEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1141428 DQN42_RS02275 WP_003078363.1 449691..450992(+) (comFA/cflA) [Streptococcus intermedius strain NCTC11324]
ATGATAGAATTACAAGACTATTTAGGTCGTATCTTTACAAGAAGCCAATTACCATTAGGATTGCAGCAACAAGCTCAAAC
ATTGTCGGGAATGATAGAAAAAAAGGGGAAATTATGGTGCAATCGTTGTGGACAAGTAGTTAATAAAGAAAAACAGCAAC
TACCAATAGGTGCTTATTATTGCAGGTCATGTGTGCGATTAGGAAGGGTCAGAAGTGATGAAAAACTCTACTATTTTCCA
CAAGCAGAGTTCCCAAAAACGAATGTTTTGACATGGGAAGGAAGGTTAACAGATTACCAAGCTAAGGTTTCTCAAGGTCT
TGTAGAGGCAGTTGCCAAACAAAAAAATAGCCTGGTTCATGCTGTCACGGGAGCCGGAAAGACGGAAATGATTTATCAAG
TGGTGGCACAAGTTATCAATGAAGGTGGTGCAGTTTGCTTGGCTAGCCCTCGAATTGATGTCTGTCTAGAACTACATCGC
AGATTGCAAGAAGATTTTAGTTGTGATATTGCACTCCTGCACGGTGAATCAGAAGTTTATTTTCGCAGTCCTCTTGTGAT
TGCCACAACGCATCAGCTTCTCAAATTTTACCGAGCATTTGATCTTCTTATTGTTGACGAGGTGGACGCCTTTCCTTATG
TGGATAATCCGATGCTTTACCATGCCGTTACACAATCAGTAAAAGAGCAAAGTACTATAATATTTCTAACGGCAACCTCT
ACAGATGAGCTGGATAAAAAAGTTAGCAAGGGAGAGTTGAACCGCTTAAGTCTCCCTAGACGTTTTCATGGTAACCCTTT
AATTGTTCCTAAAAAAGTTTGGTTGGAAAATTTTCAAAAATACCTGAATCAAAAAAAGCTAGTTCCTAAGTTGGAACAAT
TTGTTAAAAAGCAAAGAAAAACAGGTTTTCCTCTTCTCATTTTTGCTTCTGAGATTAAAAGAGGACAAGAATTGGCAGAG
GTTCTCCAAAGTTATTTTTCCAGTGAGAACGTTGGCTTTGTAGCCTCAACGACTGAAAATCGACTCGATATTGTAGAGAA
ATTTCGACAAAAAGAGATTACAATTTTAGTAACAACGACAATTCTAGAACGTGGTGTGACTTTTCCTTGTGTAGATGTTT
TTGTGGTGGAGGCTAACCACCGTTTGTTTAGTCGCAGTGCTCTGGTACAAATAGCTGGACGCGTTGGTCGCAGTATGGAT
CGTCCGACAGGTGAGCTGCTCTTTTTTCATGATGGGACCAATTTTGCTATTGAACGAGCTATTCAGGAAATTAAGGCGAT
GAATCAGGAGGCTGGTTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-397)

DEAD/DEAH box helicase (DEAD)

(98-245)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

70.093

98.845

0.693
  comFA/cflA Streptococcus pneumoniae D39

70.093

98.845

0.693
  comFA/cflA Streptococcus pneumoniae R6

70.093

98.845

0.693
  comFA/cflA Streptococcus pneumoniae TIGR4

69.86

98.845

0.691
  comFA/cflA Streptococcus mitis NCTC 12261

69.86

98.845

0.691
  comFA/cflA Streptococcus mitis SK321

68.925

98.845

0.681
  comFA Lactococcus lactis subsp. cremoris KW2

54.02

91.917

0.497
  comFA Latilactobacillus sakei subsp. sakei 23K

40.465

99.307

0.402
  comFA Bacillus subtilis subsp. subtilis str. 168

39.012

93.533

0.365

Multiple sequence alignment