Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   DQN49_RS04530 Genome accession   NZ_LS483429
Coordinates   844156..845373 (+) Length   405 a.a.
NCBI ID   WP_006996186.1    Uniprot ID   -
Organism   Haemophilus aegyptius strain NCTC8502     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 839156..850373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN49_RS04510 (NCTC8502_00921) corC 840122..841021 (-) 900 WP_006996182.1 CNNM family magnesium/cobalt transport protein CorC -
  DQN49_RS04515 (NCTC8502_00922) ampD 841644..842204 (-) 561 WP_006996183.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  DQN49_RS04520 (NCTC8502_00923) pilA 842319..842768 (+) 450 WP_006996184.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  DQN49_RS04525 (NCTC8502_00924) pilB 842765..844159 (+) 1395 WP_006996185.1 GspE/PulE family protein Machinery gene
  DQN49_RS04530 (NCTC8502_00925) pilC 844156..845373 (+) 1218 WP_006996186.1 type II secretion system F family protein Machinery gene
  DQN49_RS04535 (NCTC8502_00926) pilD 845370..846062 (+) 693 WP_006996187.1 A24 family peptidase Machinery gene
  DQN49_RS04540 (NCTC8502_00927) rho 846118..847380 (-) 1263 WP_006996188.1 transcription termination factor Rho -
  DQN49_RS04545 (NCTC8502_00928) metJ 847615..847932 (+) 318 WP_006996189.1 met regulon transcriptional regulator MetJ -
  DQN49_RS04550 (NCTC8502_00929) cueR 847946..848332 (-) 387 WP_005654127.1 Cu(I)-responsive transcriptional regulator -
  DQN49_RS04555 (NCTC8502_00930) - 848409..848615 (+) 207 WP_005654130.1 heavy-metal-associated domain-containing protein -
  DQN49_RS04560 (NCTC8502_00931) - 848701..848907 (+) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46062.27 Da        Isoelectric Point: 9.9810

>NTDB_id=1141231 DQN49_RS04530 WP_006996186.1 844156..845373(+) (pilC) [Haemophilus aegyptius strain NCTC8502]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNKWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLSAVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQTWF
HQKKNQLISVTPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=1141231 DQN49_RS04530 WP_006996186.1 844156..845373(+) (pilC) [Haemophilus aegyptius strain NCTC8502]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTA
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACAAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTTCCGCTGTTTGTAAAAAAATAGCCACACATCGTAGCCAATCTTTAGCATTACAACGTAAATTACAGAAA
ATTATGTTGTACCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACCGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAACCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTGATCATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.537

100

0.978
  pilC Haemophilus influenzae Rd KW20

96.305

100

0.965
  pilC Glaesserella parasuis strain SC1401

38.25

98.765

0.378

Multiple sequence alignment