Detailed information NTG1141034

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: DQN31_RS00690
• Genome accession: NZ_LS483421
• Coordinates: 104519..104953 (+)
• Length: 144 a.a.
• NCBI ID: WP_014407215.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC10877
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 99519..109953

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN31_RS00660 (NCTC10877_00132)	-	101202..101567 (+)	366	WP_002986560.1	DUF1033 family protein	-
DQN31_RS00665 (NCTC10877_00133)	comGA	101660..102584 (+)	925	Protein_81	competence type IV pilus ATPase ComGA	-
DQN31_RS00670 (NCTC10877_00134)	comYB	102520..103554 (+)	1035	WP_227868709.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQN31_RS00675 (NCTC10877_00135)	comGC	103556..103882 (+)	327	WP_014407214.1	competence type IV pilus major pilin ComGC	Machinery gene
DQN31_RS00680 (NCTC10877_00136)	comGD	103857..104285 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
DQN31_RS00685 (NCTC10877_00137)	comGE	104242..104526 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
DQN31_RS00690 (NCTC10877_00138)	comYF	104519..104953 (+)	435	WP_014407215.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQN31_RS00695 (NCTC10877_00139)	comGG	104937..105263 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
DQN31_RS00700 (NCTC10877_00140)	comYH	105361..106314 (+)	954	WP_014407216.1	class I SAM-dependent methyltransferase	Machinery gene
DQN31_RS00705 (NCTC10877_00141)	-	106373..107569 (+)	1197	WP_014407217.1	acetate kinase	-
DQN31_RS00710	-	107756..108064 (+)	309	WP_041174321.1	hypothetical protein	-
DQN31_RS00715 (NCTC10877_00142)	proC	108147..108917 (-)	771	WP_014407219.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16542.20 Da
• Isoelectric Point: 10.0827

>NTDB_id=1141034 DQN31_RS00690 WP_014407215.1 104519..104953(+) (comYF) [Streptococcus pyogenes strain NCTC10877]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLALHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=1141034 DQN31_RS00690 WP_014407215.1 104519..104953(+) (comYF) [Streptococcus pyogenes strain NCTC10877]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTTGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCTTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (47-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	46.715	95.139	0.444
comGF/cglF	Streptococcus mitis NCTC 12261	44.776	93.056	0.417
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396