Detailed information NTG1140937

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: DQM62_RS00790
• Genome accession: NZ_LS483418
• Coordinates: 116668..117102 (+)
• Length: 144 a.a.
• NCBI ID: WP_011922561.1
• Uniprot ID: -
• Organism: Streptococcus suis strain NCTC10234
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 111668..122102

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM62_RS00755 (NCTC10234_00146)	-	112417..112782 (+)	366	WP_002936568.1	DUF1033 family protein	-
DQM62_RS00760 (NCTC10234_00147)	-	112817..113760 (-)	944	Protein_106	S66 family peptidase	-
DQM62_RS00765 (NCTC10234_00148)	comYA	113846..114796 (+)	951	WP_011921718.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM62_RS00770 (NCTC10234_00149)	comYB	114708..115745 (+)	1038	WP_011921719.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM62_RS00775 (NCTC10234_00150)	comYC	115747..116028 (+)	282	WP_011921720.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM62_RS00780 (NCTC10234_00151)	comGD	116009..116416 (+)	408	WP_011921721.1	competence type IV pilus minor pilin ComGD	-
DQM62_RS00785 (NCTC10234_00152)	comYE	116388..116681 (+)	294	WP_011921722.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQM62_RS00790 (NCTC10234_00153)	comGF/cglF	116668..117102 (+)	435	WP_011922561.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM62_RS00795 (NCTC10234_00154)	comGG	117080..117490 (+)	411	WP_011921724.1	competence type IV pilus minor pilin ComGG	-
DQM62_RS00800 (NCTC10234_00155)	comYH	117547..118500 (+)	954	WP_011922562.1	class I SAM-dependent methyltransferase	Machinery gene
DQM62_RS00805 (NCTC10234_00156)	-	118550..119737 (+)	1188	WP_012775473.1	acetate kinase	-
DQM62_RS00810 (NCTC10234_00157)	-	120051..120602 (+)	552	WP_012775474.1	folate family ECF transporter S component	-
DQM62_RS00815 (NCTC10234_00158)	-	120658..121914 (+)	1257	WP_012775475.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16491.85 Da
• Isoelectric Point: 5.9234

>NTDB_id=1140937 DQM62_RS00790 WP_011922561.1 116668..117102(+) (comGF/cglF) [Streptococcus suis strain NCTC10234]
MLKSKIPAFTLLECLVVLVILSGSLLIFEGLSKLLVQEAHYQGQTVQKEWLVFSSQLRSEWDQAELVKVENGKVYVNKGE
QALAFGKSWSDDFRKTNDRGQGYQPMLYQVDSAAISQENQLVRIDFSFKNGEERTFIYAFKEKS

Nucleotide

• Length: 435 bp

>NTDB_id=1140937 DQM62_RS00790 WP_011922561.1 116668..117102(+) (comGF/cglF) [Streptococcus suis strain NCTC10234]
TTGTTAAAAAGTAAAATTCCTGCTTTTACACTCTTGGAATGTTTGGTGGTTCTAGTCATTCTGTCAGGTAGCCTCTTGAT
TTTTGAAGGCTTATCCAAATTACTAGTCCAGGAAGCGCATTATCAAGGTCAGACCGTTCAAAAGGAATGGTTGGTCTTCT
CTAGCCAATTGCGGTCGGAGTGGGACCAGGCTGAATTGGTCAAGGTTGAAAATGGCAAGGTCTATGTCAACAAAGGTGAA
CAGGCTTTGGCCTTTGGCAAGTCATGGTCGGATGATTTTCGGAAAACAAATGATAGAGGCCAGGGTTACCAACCCATGCT
CTATCAGGTGGATAGCGCAGCCATTTCCCAAGAAAACCAGCTGGTGCGCATCGACTTTAGCTTTAAAAACGGAGAGGAGC
GAACCTTTATCTATGCTTTTAAAGAAAAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae TIGR4	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae Rx1	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae D39	52.482	97.917	0.514
comGF/cglF	Streptococcus pneumoniae R6	52.482	97.917	0.514
comGF/cglF	Streptococcus mitis NCTC 12261	52.985	93.056	0.493
comYF	Streptococcus mutans UA140	48.611	100	0.486
comYF	Streptococcus mutans UA159	47.917	100	0.479
comGF/cglF	Streptococcus mitis SK321	50	93.056	0.465
comGF	Lactococcus lactis subsp. cremoris KW2	45.39	97.917	0.444