Detailed information NTG1140886

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: DQN54_RS08795
• Genome accession: NZ_LS483417
• Coordinates: 1657446..1658105 (+)
• Length: 219 a.a.
• NCBI ID: WP_000565023.1
• Uniprot ID: A0A0I8D2P0
• Organism: Streptococcus pneumoniae strain NCTC11902
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1652446..1663105

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN54_RS08770 (NCTC11902_01681)	-	1652751..1653068 (-)	318	WP_001151646.1	PTS sugar transporter subunit IIB	-
DQN54_RS08775 (NCTC11902_01682)	-	1653083..1653979 (-)	897	WP_000825669.1	PEP phosphonomutase	-
DQN54_RS08780 (NCTC11902_01683)	-	1653982..1655244 (-)	1263	WP_000413336.1	PTS sugar transporter subunit IIC	-
DQN54_RS08785 (NCTC11902_01684)	-	1655524..1656702 (+)	1179	WP_000175886.1	ROK family transcriptional regulator	-
DQN54_RS08790 (NCTC11902_01685)	-	1656930..1657376 (-)	447	WP_000155406.1	GNAT family N-acetyltransferase	-
DQN54_RS08795 (NCTC11902_01686)	cclA/cilC	1657446..1658105 (+)	660	WP_000565023.1	prepilin peptidase	Machinery gene
DQN54_RS08800 (NCTC11902_01687)	trpA	1658077..1658853 (-)	777	WP_001126995.1	tryptophan synthase subunit alpha	-
DQN54_RS08805 (NCTC11902_01688)	trpB	1658846..1660069 (-)	1224	WP_000331298.1	tryptophan synthase subunit beta	-
DQN54_RS08810 (NCTC11902_01689)	-	1660047..1660646 (-)	600	WP_000169872.1	phosphoribosylanthranilate isomerase	-
DQN54_RS08815 (NCTC11902_01690)	trpC	1660633..1661400 (-)	768	WP_000076544.1	indole-3-glycerol phosphate synthase TrpC	-
DQN54_RS08820 (NCTC11902_01691)	trpD	1661397..1662401 (-)	1005	WP_000658684.1	anthranilate phosphoribosyltransferase	-
DQN54_RS08825 (NCTC11902_01692)	-	1662412..1662978 (-)	567	WP_000601930.1	aminodeoxychorismate/anthranilate synthase component II	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24921.13 Da
• Isoelectric Point: 8.2409

>NTDB_id=1140886 DQN54_RS08795 WP_000565023.1 1657446..1658105(+) (cclA/cilC) [Streptococcus pneumoniae strain NCTC11902]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWKLLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=1140886 DQN54_RS08795 WP_000565023.1 1657446..1658105(+) (cclA/cilC) [Streptococcus pneumoniae strain NCTC11902]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGAAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-89)

3D structure

• AlphaFold DB: A0A0I8D2P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	97.717	100	0.977
cclA/cilC	Streptococcus pneumoniae Rx1	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae D39	96.347	100	0.963
cclA/cilC	Streptococcus pneumoniae R6	96.347	100	0.963
cclA/cilC	Streptococcus mitis SK321	92.237	100	0.922
cclA/cilC	Streptococcus mitis NCTC 12261	86.301	100	0.863