Detailed information NTG1140700

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: DQN40_RS03280
• Genome accession: NZ_LS483413
• Coordinates: 623709..624416 (+)
• Length: 235 a.a.
• NCBI ID: WP_003055001.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 618709..629416

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQN40_RS03250 (NCTC7136_00667)	-	618735..620159 (+)	1425	WP_084916428.1	glycoside hydrolase family 1 protein	-
DQN40_RS03255 (NCTC7136_00668)	-	620258..621073 (-)	816	WP_042357866.1	TIGR03943 family protein	-
DQN40_RS03260 (NCTC7136_00669)	-	621073..621975 (-)	903	WP_002990594.1	permease	-
DQN40_RS03265 (NCTC7136_00670)	-	622123..622278 (-)	156	WP_111678984.1	SPJ_0845 family protein	-
DQN40_RS03270 (NCTC7136_00671)	-	622357..622968 (-)	612	WP_015016795.1	NUDIX hydrolase N-terminal domain-containing protein	-
DQN40_RS03275 (NCTC7136_00672)	-	623140..623622 (+)	483	WP_015016796.1	cupin domain-containing protein	-
DQN40_RS03280 (NCTC7136_00673)	vicR	623709..624416 (+)	708	WP_003055001.1	response regulator transcription factor	Regulator
DQN40_RS03285 (NCTC7136_00674)	-	624417..625745 (+)	1329	WP_012766697.1	ATP-binding protein	-
DQN40_RS03290 (NCTC7136_00675)	-	625912..626787 (+)	876	WP_014612110.1	substrate-binding domain-containing protein	-
DQN40_RS03295 (NCTC7136_00676)	pstC	626904..627767 (+)	864	WP_012766699.1	phosphate ABC transporter permease subunit PstC	-
DQN40_RS03300 (NCTC7136_00677)	pstA	627760..628575 (+)	816	WP_003060853.1	phosphate ABC transporter permease PstA	-
DQN40_RS03305 (NCTC7136_00678)	pstB	628577..629329 (+)	753	WP_003055005.1	phosphate ABC transporter ATP-binding protein PstB	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27491.70 Da
• Isoelectric Point: 5.4461

>NTDB_id=1140700 DQN40_RS03280 WP_003055001.1 623709..624416(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
MTKQILLVDDEEHILRLLDYHLGKEGFSTQLVTDGRKALTLAETEPFDFILLDIMLPQLDGIEVCKRLRAKGIKTPIMMV
SAKSDEFDKVLALELGADDYLTKPFSPRELLARVKAILRRTSKEQQEDDTDDFRDDYRVFGALTVYPDRHEVYKADHLLS
LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLRDKIEDNPKDPQFIQTIRGYGYKFKEL

Nucleotide

• Length: 708 bp

>NTDB_id=1140700 DQN40_RS03280 WP_003055001.1 623709..624416(+) (vicR) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC7136]
ATGACAAAACAAATCTTATTAGTGGATGATGAAGAACACATTTTGAGGCTACTGGATTATCATCTCGGTAAAGAAGGGTT
TTCCACACAATTGGTAACAGATGGCCGAAAAGCATTGACATTGGCAGAAACAGAGCCTTTTGACTTTATCCTACTGGATA
TTATGTTGCCTCAGTTAGACGGCATAGAAGTGTGTAAGCGACTGAGAGCTAAAGGAATAAAAACTCCGATTATGATGGTT
TCTGCTAAAAGTGATGAATTTGATAAGGTTTTGGCCTTGGAATTAGGAGCTGATGACTACCTGACTAAGCCTTTTAGCCC
TAGAGAATTGCTGGCGCGTGTCAAGGCTATTTTACGTCGAACCAGTAAAGAGCAGCAAGAAGATGACACAGATGATTTCA
GGGATGATTATCGGGTATTTGGGGCCCTGACCGTCTATCCAGACCGGCATGAGGTTTATAAGGCAGATCATTTATTGAGC
CTTACCCCAAAGGAATTTGAACTCTTGCTCTATCTTATGAAACATCCCAACATGACATTAACTAGGGAACGTTTACTTGA
ACGGATTTGGGGATATGATTTTGGACAAGAAACCCGTTTAGTGGATGTTCATATTGGCAAATTGAGAGATAAGATAGAGG
ATAATCCTAAAGACCCTCAATTTATTCAAACGATTAGAGGCTATGGGTATAAGTTTAAGGAGTTATAG

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (159-232)

• Response regulator receiver domain (Response_reg) (5-115)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	49.145	99.574	0.489
micA	Streptococcus pneumoniae Cp1015	47.619	98.298	0.468
covR	Lactococcus lactis subsp. lactis strain DGCC12653	41.772	100	0.421
covR	Streptococcus salivarius strain HSISS4	40.506	100	0.409