Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE1   Type   Regulator
Locus tag   DQN21_RS11100 Genome accession   NZ_LS483409
Coordinates   2219682..2220413 (-) Length   243 a.a.
NCBI ID   WP_077497729.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2214682..2225413
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS11065 (NCTC13773_02248) comE/comE2 2215462..2216190 (-) 729 WP_012962512.1 LytR/AlgR family response regulator transcription factor Regulator
  DQN21_RS11070 (NCTC13773_02249) - 2216289..2216582 (-) 294 WP_009854994.1 bacteriocin immunity protein -
  DQN21_RS11075 (NCTC13773_02250) - 2216633..2216785 (-) 153 WP_231873055.1 hypothetical protein -
  DQN21_RS11080 (NCTC13773_02251) - 2217129..2217440 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  DQN21_RS11085 (NCTC13773_02252) - 2217452..2217601 (-) 150 WP_013643483.1 hypothetical protein -
  DQN21_RS11090 (NCTC13773_02253) - 2217658..2217909 (-) 252 WP_231844599.1 DUF3884 family protein -
  DQN21_RS12630 (NCTC13773_02254) - 2218210..2218350 (+) 141 WP_014295304.1 hypothetical protein -
  DQN21_RS11095 (NCTC13773_02255) - 2218367..2219677 (-) 1311 WP_058621373.1 sensor histidine kinase -
  DQN21_RS11100 (NCTC13773_02256) comE/comE1 2219682..2220413 (-) 732 WP_077497729.1 response regulator transcription factor Regulator
  DQN21_RS11105 (NCTC13773_02257) - 2220430..2220756 (-) 327 WP_009855002.1 LytTR family DNA-binding domain-containing protein -
  DQN21_RS11110 (NCTC13773_02258) - 2220940..2222232 (-) 1293 WP_013643489.1 glycosyltransferase family 2 protein -
  DQN21_RS11115 (NCTC13773_02259) - 2222234..2222533 (-) 300 WP_013643490.1 DUF3884 family protein -
  DQN21_RS11120 (NCTC13773_02260) - 2222559..2222741 (-) 183 WP_013643491.1 hypothetical protein -
  DQN21_RS11125 (NCTC13773_02261) - 2222823..2223032 (-) 210 WP_013643492.1 helix-turn-helix domain-containing protein -
  DQN21_RS11130 (NCTC13773_02262) - 2223022..2224035 (-) 1014 WP_077497732.1 bacteriocin biosynthesis protein -
  DQN21_RS11150 (NCTC13773_02263) - 2225093..2225290 (-) 198 WP_009855009.1 class IIb bacteriocin, lactobin A/cerein 7B family -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 28458.68 Da        Isoelectric Point: 5.6935

>NTDB_id=1140588 DQN21_RS11100 WP_077497729.1 2219682..2220413(-) (comE/comE1) [Streptococcus gallolyticus strain NCTC13773]
MLDIYVLEDNIIQQFRMEREIATIMAKNNWDYRKLEMFGSANEIIAKATEKGEHQIFFLDLEIRDDEKQGIDVAKAIREK
DATAIIVFVTTHSEFMLLTYQALVGAIDFIDKNLNDQAFSERIELCLKEAMKHQNDNFGENSFLFETPKARVRMPYSDIL
YFETSPAVHRVIMHTKNDRMEFYATIAEIAKSDKRLFKCHRSFIINVDNVVRFDKATRSVYFETGDTCLVSRDKIKPLLN
EMR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=1140588 DQN21_RS11100 WP_077497729.1 2219682..2220413(-) (comE/comE1) [Streptococcus gallolyticus strain NCTC13773]
ATGTTAGATATTTATGTACTAGAGGATAATATCATACAGCAATTTCGTATGGAACGCGAGATTGCGACCATTATGGCAAA
AAATAATTGGGACTATCGAAAGTTAGAAATGTTTGGCTCTGCAAATGAGATTATAGCTAAGGCAACTGAAAAAGGAGAGC
ATCAAATTTTCTTTCTTGATTTAGAAATCAGAGACGACGAAAAACAAGGAATTGATGTCGCTAAAGCTATTCGTGAAAAA
GATGCAACAGCTATCATTGTTTTTGTAACAACTCATTCAGAATTTATGCTGCTGACCTACCAAGCGTTAGTAGGGGCAAT
TGATTTTATTGATAAGAACCTGAATGACCAAGCATTTAGTGAACGCATAGAGTTGTGCCTAAAGGAAGCCATGAAACATC
AAAATGATAATTTCGGCGAAAACTCCTTTTTATTTGAAACTCCTAAAGCACGTGTGCGCATGCCATATAGTGACATTCTC
TATTTTGAAACCTCTCCTGCTGTGCACCGCGTGATTATGCATACGAAAAATGACAGAATGGAATTTTATGCAACGATTGC
AGAGATTGCTAAATCAGACAAACGTCTTTTTAAGTGTCATCGTTCTTTTATCATTAATGTGGATAATGTGGTCAGATTTG
ATAAAGCGACACGAAGTGTTTATTTCGAAACTGGGGACACTTGCCTAGTTTCTAGAGATAAAATAAAACCTCTATTAAAT
GAGATGAGGTGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(152-238)

Response regulator receiver domain (Response_reg)

(12-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE1 Streptococcus equinus JB1

71.193

100

0.712
  comE/blpR Streptococcus mutans UA159

48.536

98.354

0.477
  comE/comE2 Streptococcus equinus JB1

47.107

99.588

0.469

Multiple sequence alignment