Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQN21_RS10130 Genome accession   NZ_LS483409
Coordinates   2031411..2032103 (-) Length   230 a.a.
NCBI ID   WP_009854820.1    Uniprot ID   A0A139QWD3
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2026411..2037103
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS10110 (NCTC13773_02056) dnaI 2027186..2028088 (-) 903 WP_009854816.1 primosomal protein DnaI -
  DQN21_RS10115 (NCTC13773_02057) - 2028099..2029256 (-) 1158 WP_074658080.1 DnaD domain protein -
  DQN21_RS10120 (NCTC13773_02058) nrdR 2029240..2029737 (-) 498 WP_009854818.1 transcriptional regulator NrdR -
  DQN21_RS10125 (NCTC13773_02059) - 2029927..2031411 (-) 1485 WP_012962415.1 sensor histidine kinase -
  DQN21_RS10130 (NCTC13773_02060) covR 2031411..2032103 (-) 693 WP_009854820.1 response regulator transcription factor Regulator
  DQN21_RS10135 (NCTC13773_02061) - 2032341..2032877 (-) 537 WP_013643366.1 YceD family protein -
  DQN21_RS10140 (NCTC13773_02062) htpX 2033019..2033921 (-) 903 WP_009854824.1 zinc metalloprotease HtpX -
  DQN21_RS10145 (NCTC13773_02063) - 2034048..2034599 (-) 552 WP_012962418.1 LemA family protein -
  DQN21_RS10150 (NCTC13773_02064) rsmG 2034930..2035643 (+) 714 WP_043913877.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQN21_RS10155 (NCTC13773_02065) - 2035713..2037086 (+) 1374 WP_013643370.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26487.39 Da        Isoelectric Point: 4.7059

>NTDB_id=1140582 DQN21_RS10130 WP_009854820.1 2031411..2032103(-) (covR) [Streptococcus gallolyticus strain NCTC13773]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKETSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDVESKREQDSQGKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1140582 DQN21_RS10130 WP_009854820.1 2031411..2032103(-) (covR) [Streptococcus gallolyticus strain NCTC13773]
ATGAGTAAAAAGATTTTAATTATTGAAGATGAAAAAAATCTTGCACGCTTTGTGTCTTTGGAGTTACAACACGAAGGTTA
TTCTGTAGTTGTAGAAACAAACGGGCGCTTAGGGCTTCAAACGGCTCTTGATGACGATTTTGACTTGATTTTGCTTGATT
TAATGCTTCCAGATATGGATGGATTTGAAATCACGCGTCGTCTTCGATTGGAAAAAGAAACTTCTATTATTATGATGACA
GCTCGCGACTCTATTATGGATATTGTTGCTGGGCTTGATCGTGGTGCAGATGACTATATTGTCAAACCATTTGCAATTGA
AGAACTCTTGGCTCGTGTTCGTGCTGTTTTCCGCCGTCAAGATGTTGAATCTAAACGTGAACAAGACAGTCAAGGAAAAG
AAGGATTGCTTGGTCTACGCTTAAATCCTCAAAATCGTTCAGCGGTTCGAGGTGATGATGAAATTTCGCTTACAAAACGT
GAGTACGATTTGTTAAGTGTTCTTTTGTCAAATGTTAATCGTGTAATGACACGTGAAGAACTGCTAGCCAGTGTTTGGAG
ATACGATACAGATATTGAGACAAATGTTGTTGATGTTTATATCCGTTACCTTCGCGGAAAAGTCGATATTCCAGGTAAAG
AATCTTACATTCAAACAGTTCGTGGAATGGGATACATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A139QWD3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

75.217

100

0.752
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.755

99.565

0.635
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.422

Multiple sequence alignment