Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQN33_RS04945 Genome accession   NZ_LS483408
Coordinates   972929..974239 (-) Length   436 a.a.
NCBI ID   WP_037592122.1    Uniprot ID   -
Organism   Streptococcus uberis strain NCTC4674     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 967929..979239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN33_RS04915 (NCTC4674_01017) - 968453..968839 (-) 387 WP_307935650.1 cytidine deaminase -
  DQN33_RS04920 (NCTC4674_01018) deoC 968829..969491 (-) 663 WP_012658451.1 deoxyribose-phosphate aldolase -
  DQN33_RS04925 (NCTC4674_01019) - 969502..970779 (-) 1278 WP_012658452.1 pyrimidine-nucleoside phosphorylase -
  DQN33_RS04930 (NCTC4674_01020) - 970776..971366 (-) 591 WP_012658453.1 class I SAM-dependent methyltransferase -
  DQN33_RS04935 (NCTC4674_01021) coaA 971630..972550 (+) 921 WP_046389364.1 type I pantothenate kinase -
  DQN33_RS04940 (NCTC4674_01022) rpsT 972610..972852 (+) 243 WP_160463058.1 30S ribosomal protein S20 -
  DQN33_RS04945 (NCTC4674_01023) ciaH 972929..974239 (-) 1311 WP_037592122.1 sensor histidine kinase Regulator
  DQN33_RS04950 (NCTC4674_01024) ciaR 974232..974906 (-) 675 WP_012658457.1 response regulator transcription factor Regulator
  DQN33_RS04955 (NCTC4674_01025) - 975028..977565 (-) 2538 WP_046390250.1 M1 family metallopeptidase -
  DQN33_RS04960 (NCTC4674_01026) phoU 977635..978288 (-) 654 WP_012658459.1 phosphate signaling complex protein PhoU -
  DQN33_RS04965 (NCTC4674_01027) pstB 978308..979066 (-) 759 WP_012658460.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 50104.14 Da        Isoelectric Point: 7.6210

>NTDB_id=1140510 DQN33_RS04945 WP_037592122.1 972929..974239(-) (ciaH) [Streptococcus uberis strain NCTC4674]
MTKYKELLKSDNFNHFSHYFSVFTGIFAVMTFIILQIMKFGVYSSVDSSLLTVAKNSENYTNKTMERISSFYFDNQSGHF
KASTEAFKIKNDNEPVANTDILLFSSNGIVINSFDALSNFQNFTLNKNELNTIQTQKLVNYYGHEEKFHTITVRVHSKNY
PAIAYMMAVVNVEQSEKTNERYEKFIIIVMIVFWLISIIASIYLANWSSKPIIESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNESILDNSEAIASSLDEVRNMRILTTNLLNLARRDDGIKPDWEEIDAQFFNSIFENYSLIAEENGKSFQFDN
QVHRKVKTDKALLKQLLTILFDNAIKYTDADGEIEIQVSTGDKHLYLTVLDNGPGINDIDKKKIFDRFYRVDKARTRSKG
GFGLGLALAQQIVQSLKGSIVVKDNRPKGTIFEVKF

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1140510 DQN33_RS04945 WP_037592122.1 972929..974239(-) (ciaH) [Streptococcus uberis strain NCTC4674]
ATGACTAAATATAAAGAATTACTTAAATCCGATAATTTCAATCACTTTTCCCATTATTTTTCTGTATTTACGGGCATTTT
TGCGGTTATGACTTTCATTATCCTTCAGATCATGAAATTTGGTGTCTATTCATCTGTTGATAGTAGTTTATTGACAGTTG
CCAAGAATTCAGAGAATTATACCAACAAGACCATGGAGAGGATTTCTTCCTTTTATTTTGATAACCAAAGTGGTCATTTT
AAAGCTAGTACAGAAGCATTTAAAATAAAGAATGATAATGAGCCGGTTGCAAATACAGATATCTTACTCTTTAGTTCAAA
CGGTATTGTTATCAACAGTTTTGATGCGCTTTCCAATTTTCAAAATTTTACGCTGAATAAAAACGAATTAAATACGATTC
AAACGCAAAAATTAGTCAATTACTATGGCCATGAAGAAAAATTTCATACCATTACAGTAAGGGTACATTCCAAAAACTAC
CCTGCAATCGCCTATATGATGGCCGTAGTAAATGTTGAACAGTCAGAAAAAACAAATGAACGATATGAGAAATTTATCAT
AATCGTTATGATTGTGTTCTGGCTCATTTCCATTATTGCTAGTATATATCTGGCAAATTGGAGTAGTAAGCCTATCATTG
AGAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCCAGTCATGAATTAAGGACGCCTTTGGCCGTTTTACAGAATCGT
TTAGAAAGTTTATTTCGAAAGCCAAACGAGAGTATTCTTGATAATAGCGAAGCCATTGCGTCAAGCTTAGATGAAGTCAG
AAATATGAGAATACTAACCACTAATCTTCTTAATCTTGCGAGACGTGATGATGGTATAAAACCCGACTGGGAAGAAATTG
ATGCTCAATTCTTTAATAGTATTTTTGAAAATTATAGCCTTATTGCAGAAGAAAATGGCAAATCATTCCAGTTTGATAAT
CAAGTTCATAGAAAAGTAAAAACTGATAAAGCTCTACTCAAACAATTGTTAACGATTCTTTTTGACAATGCCATAAAATA
TACTGATGCTGACGGTGAGATTGAAATACAGGTTTCAACTGGGGATAAACATCTCTATCTTACTGTCTTAGATAATGGAC
CTGGCATTAATGATATTGACAAAAAGAAAATTTTTGACAGATTCTATAGAGTCGATAAAGCCAGAACAAGAAGTAAGGGT
GGATTTGGATTAGGATTAGCCTTAGCTCAACAAATCGTTCAATCTTTAAAAGGAAGTATTGTCGTTAAGGATAATAGGCC
TAAAGGGACAATTTTTGAAGTCAAATTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.881

100

0.569
  ciaH Streptococcus pneumoniae Rx1

50.575

99.771

0.505
  ciaH Streptococcus pneumoniae D39

50.575

99.771

0.505
  ciaH Streptococcus pneumoniae R6

50.575

99.771

0.505
  ciaH Streptococcus pneumoniae TIGR4

50.575

99.771

0.505

Multiple sequence alignment