Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQN23_RS07200 Genome accession   NZ_LS483403
Coordinates   1431493..1432185 (-) Length   230 a.a.
NCBI ID   WP_020917358.1    Uniprot ID   A0AB33ANI4
Organism   Streptococcus lutetiensis strain NCTC13774     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1426493..1437185
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN23_RS07180 (NCTC13774_01501) dnaI 1427297..1428199 (-) 903 WP_020917355.1 primosomal protein DnaI -
  DQN23_RS07185 (NCTC13774_01502) - 1428210..1429361 (-) 1152 WP_111712972.1 DnaD domain protein -
  DQN23_RS07190 (NCTC13774_01503) nrdR 1429348..1429842 (-) 495 WP_006532915.1 transcriptional regulator NrdR -
  DQN23_RS07195 (NCTC13774_01504) - 1430024..1431493 (-) 1470 WP_058832789.1 HAMP domain-containing histidine kinase -
  DQN23_RS07200 (NCTC13774_01505) covR 1431493..1432185 (-) 693 WP_020917358.1 response regulator transcription factor Regulator
  DQN23_RS07205 (NCTC13774_01506) - 1432426..1432962 (-) 537 WP_058814197.1 DUF177 domain-containing protein -
  DQN23_RS07210 (NCTC13774_01507) htpX 1433104..1434003 (-) 900 WP_111712973.1 zinc metalloprotease HtpX -
  DQN23_RS07215 (NCTC13774_01508) - 1434116..1434667 (-) 552 WP_014335211.1 LemA family protein -
  DQN23_RS07220 (NCTC13774_01509) rsmG 1434961..1435674 (+) 714 WP_020917362.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQN23_RS07225 (NCTC13774_01510) - 1435740..1437113 (+) 1374 WP_058832791.1 TrkH family potassium uptake protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26356.30 Da        Isoelectric Point: 4.8466

>NTDB_id=1140362 DQN23_RS07200 WP_020917358.1 1431493..1432185(-) (covR) [Streptococcus lutetiensis strain NCTC13774]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVETNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLEKDTSIIMMT
ARDSIMDIVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDANSKQAKEGQAKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLASVWRYDTDIETNVVDVYIRYLRGKIDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=1140362 DQN23_RS07200 WP_020917358.1 1431493..1432185(-) (covR) [Streptococcus lutetiensis strain NCTC13774]
ATGAGTAAAAAGATTTTAATTATTGAGGATGAAAAAAATCTTGCACGCTTTGTGTCTTTAGAATTACAACATGAGGGGTA
TTCAGTAGTTGTTGAGACAAATGGACGTTTAGGGCTTCAAACAGCATTGGATGATGATTTTGATTTGATCCTATTAGATT
TGATGTTACCTGATATGGACGGATTCGAAATTACACGTCGTCTTCGCTTGGAAAAAGACACATCGATTATCATGATGACT
GCTCGTGATTCTATTATGGATATTGTTGCTGGTCTTGACCGTGGAGCAGATGATTACATTGTAAAACCATTTGCTATTGA
AGAATTACTGGCTCGTGTTCGTGCAGTATTCCGTCGTCAAGATGCTAATTCTAAACAAGCAAAAGAAGGTCAAGCAAAAG
AAGGTCTCTTAGGTCTTCGTTTGAACCCACAAAATCGTTCGGCAGTGCGTGGAGATGATGAAATTTCATTAACAAAACGT
GAATACGACTTGTTGAGCGTGCTTCTTTCAAATGTTAATCGCGTAATGACACGTGAAGAACTTTTGGCAAGTGTTTGGCG
TTATGATACAGACATCGAAACAAATGTCGTGGATGTTTACATCCGTTACCTACGTGGTAAAATTGATATTCCTGGTAAAG
AATCATATATCCAAACAGTTCGTGGAATGGGTTATATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

77.056

100

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

65.066

99.565

0.648
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.739

100

0.417

Multiple sequence alignment