Detailed information NTG1139901

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: DQM93_RS04620
• Genome accession: NZ_LS483390
• Coordinates: 873036..873989 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495911.1
• Uniprot ID: Q8DQ27
• Organism: Streptococcus pneumoniae strain NCTC13276
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 868036..878989

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM93_RS04595	rpmG	868779..868928 (+)	150	WP_001810029.1	50S ribosomal protein L33	-
DQM93_RS04600 (NCTC13276_00883)	secG	868968..869201 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
DQM93_RS04605 (NCTC13276_00884)	rnr	869303..871657 (+)	2355	WP_000654897.1	ribonuclease R	-
DQM93_RS04610 (NCTC13276_00885)	smpB	871620..872087 (+)	468	WP_001051750.1	SsrA-binding protein SmpB	-
DQM93_RS04615 (NCTC13276_00886)	tehB	872103..872963 (+)	861	WP_000413762.1	SAM-dependent methyltransferase TehB	-
DQM93_RS04620 (NCTC13276_00887)	coiA	873036..873989 (+)	954	WP_000495911.1	competence protein CoiA	Machinery gene
DQM93_RS04625 (NCTC13276_00888)	pepF	874008..875810 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
DQM93_RS04630 (NCTC13276_00889)	-	875812..876525 (+)	714	WP_000230399.1	O-methyltransferase	-
DQM93_RS04635 (NCTC13276_00890)	prsA	876592..877533 (+)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
DQM93_RS04640 (NCTC13276_00891)	-	877652..877993 (-)	342	Protein_875	transposase	-
DQM93_RS04650	-	878405..878500 (+)	96	Protein_876	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38143.79 Da
• Isoelectric Point: 9.1135

>NTDB_id=1139901 DQM93_RS04620 WP_000495911.1 873036..873989(+) (coiA) [Streptococcus pneumoniae strain NCTC13276]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKGKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKKQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=1139901 DQM93_RS04620 WP_000495911.1 873036..873989(+) (coiA) [Streptococcus pneumoniae strain NCTC13276]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCTTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGCTATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGGAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGCCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAAACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: Q8DQ27

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae Rx1	100	100	1
coiA	Streptococcus pneumoniae D39	100	100	1
coiA	Streptococcus pneumoniae R6	100	100	1
coiA	Streptococcus pneumoniae TIGR4	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435