Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   DQM45_RS07750 Genome accession   NZ_LS483388
Coordinates   1557912..1558598 (-) Length   228 a.a.
NCBI ID   WP_003082738.1    Uniprot ID   A0A4V0H8F5
Organism   Streptococcus porcinus strain NCTC10999     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1552912..1563598
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM45_RS07730 (NCTC10999_01574) dnaI 1553635..1554537 (-) 903 WP_003082582.1 primosomal protein DnaI -
  DQM45_RS07735 (NCTC10999_01575) - 1554538..1555725 (-) 1188 WP_003083617.1 DnaD domain protein -
  DQM45_RS07740 (NCTC10999_01576) nrdR 1555712..1556206 (-) 495 WP_003084743.1 transcriptional regulator NrdR -
  DQM45_RS07745 (NCTC10999_01577) - 1556421..1557902 (-) 1482 WP_039984627.1 HAMP domain-containing histidine kinase -
  DQM45_RS07750 (NCTC10999_01578) covR 1557912..1558598 (-) 687 WP_003082738.1 two-component system response regulator CovR Regulator
  DQM45_RS07755 (NCTC10999_01579) - 1558817..1559350 (-) 534 WP_003084706.1 DUF177 domain-containing protein -
  DQM45_RS07760 (NCTC10999_01580) htpX 1559546..1560442 (-) 897 WP_003085754.1 zinc metalloprotease HtpX -
  DQM45_RS07765 (NCTC10999_01581) - 1560476..1561030 (-) 555 WP_003084291.1 LemA family protein -
  DQM45_RS07770 (NCTC10999_01582) rsmG 1561179..1561892 (+) 714 WP_003085827.1 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG -
  DQM45_RS07775 (NCTC10999_01583) ktrB 1561977..1563353 (+) 1377 WP_003084296.1 potassium uptake transporter channel subunit KtrB -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 26623.61 Da        Isoelectric Point: 4.6541

>NTDB_id=1139807 DQM45_RS07750 WP_003082738.1 1557912..1558598(-) (covR) [Streptococcus porcinus strain NCTC10999]
MTKKILIVEDEKNLARFVSLELQHEGYEVTVEVNGREGLETALEKDFDLILLDLMLPEMDGFEVTRRLQTEKTTYIMMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARIRAIFRRQDIETEKKAPNQGVYRDLVLNPQNRSVNRGDDEISLTKREY
DLLNILMTNMNRVMTREELLSNVWKYDEAVETNVVDVYIRYLRGKIDMPGRESYIQTVRGMGYVIREK

Nucleotide


Download         Length: 687 bp        

>NTDB_id=1139807 DQM45_RS07750 WP_003082738.1 1557912..1558598(-) (covR) [Streptococcus porcinus strain NCTC10999]
ATGACAAAGAAAATTCTAATTGTCGAAGATGAAAAAAATCTCGCACGGTTTGTCTCACTTGAACTTCAACATGAAGGTTA
CGAGGTGACAGTAGAAGTAAACGGGCGTGAAGGCCTAGAAACAGCATTAGAAAAAGATTTTGATTTAATTTTACTAGATT
TAATGCTTCCAGAAATGGACGGTTTTGAGGTTACTCGTCGTCTTCAAACAGAGAAAACTACCTATATCATGATGATGACT
GCGCGTGATTCTATTATGGACGTTGTGGCAGGTCTCGATCGCGGTGCAGATGATTATATTGTCAAACCATTCGCTATTGA
AGAGTTGTTAGCACGTATTCGGGCAATTTTCCGTCGTCAAGATATTGAAACTGAAAAGAAAGCACCTAATCAAGGTGTTT
ATCGCGATCTTGTTTTGAACCCTCAAAATAGATCCGTGAACCGTGGTGATGATGAAATTTCACTAACAAAACGTGAGTAT
GATCTCTTGAATATTCTTATGACAAATATGAACCGTGTTATGACTCGAGAAGAGTTGCTTTCTAATGTTTGGAAATATGA
TGAAGCTGTTGAAACAAATGTTGTGGATGTTTACATTCGTTATCTTCGTGGTAAAATTGACATGCCTGGTCGTGAATCTT
ATATCCAGACTGTTCGTGGCATGGGTTATGTTATCCGCGAAAAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-224)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4V0H8F5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

82.969

100

0.833
  covR Lactococcus lactis subsp. lactis strain DGCC12653

66.96

99.561

0.667
  vicR Streptococcus mutans UA159

43.723

100

0.443
  micA Streptococcus pneumoniae Cp1015

43.043

100

0.434

Multiple sequence alignment