Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   DQM63_RS07575 Genome accession   NZ_LS483385
Coordinates   1532828..1534177 (-) Length   449 a.a.
NCBI ID   WP_002899938.1    Uniprot ID   -
Organism   Streptococcus sanguinis strain NCTC7863     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1527828..1539177
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM63_RS07560 (NCTC7863_01490) rnc 1530747..1531445 (-) 699 WP_002913383.1 ribonuclease III -
  DQM63_RS07565 (NCTC7863_01491) - 1531567..1531926 (-) 360 WP_002906095.1 YbaN family protein -
  DQM63_RS07570 (NCTC7863_01492) vicX 1532018..1532818 (-) 801 WP_002913382.1 MBL fold metallo-hydrolase Regulator
  DQM63_RS07575 (NCTC7863_01493) micB 1532828..1534177 (-) 1350 WP_002899938.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DQM63_RS07580 (NCTC7863_01494) micA 1534170..1534871 (-) 702 WP_002894937.1 response regulator YycF Regulator
  DQM63_RS07585 (NCTC7863_01495) - 1535208..1535969 (+) 762 WP_002913381.1 amino acid ABC transporter ATP-binding protein -
  DQM63_RS07590 (NCTC7863_01496) - 1535984..1536796 (+) 813 WP_002913380.1 transporter substrate-binding domain-containing protein -
  DQM63_RS07595 (NCTC7863_01497) - 1536809..1537489 (+) 681 WP_002913378.1 amino acid ABC transporter permease -
  DQM63_RS07600 (NCTC7863_01498) - 1537500..1538159 (+) 660 WP_002906089.1 amino acid ABC transporter permease -
  DQM63_RS07605 (NCTC7863_01499) - 1538268..1538666 (+) 399 WP_002913375.1 hypothetical protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 50975.86 Da        Isoelectric Point: 4.3896

>NTDB_id=1139637 DQM63_RS07575 WP_002899938.1 1532828..1534177(-) (micB) [Streptococcus sanguinis strain NCTC7863]
MIEAIKQFVISADFVFAIIIIGFIVVVALLLLENRRDNQKLVQLNQKVKDLIAGDYSEVLDMQGSPEITDMTNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIITINDMATKQLGVKRDEVQNMSILDLLSISDEYDLRDLITNVPE
LTIDSQDENGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSHLEVELTNFTAFITFILNRFDKIKNQDETKKYEIIRDYPITPIW
VEIDTDKLTQVIDNIMNNAIKYSPDGGTITVSIKTTDEQLILSIADEGLGIPKQDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHQGFIWAKSEYGVGSTFTIVLPYENDGVRDDDWDNEDDI

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1139637 DQM63_RS07575 WP_002899938.1 1532828..1534177(-) (micB) [Streptococcus sanguinis strain NCTC7863]
ATGATTGAAGCAATTAAACAATTTGTGATTTCTGCGGATTTTGTCTTTGCAATCATTATTATCGGCTTCATTGTAGTTGT
TGCCTTGCTTTTATTGGAAAATCGCCGTGATAACCAAAAGCTTGTACAGCTTAATCAAAAGGTTAAAGATTTGATTGCAG
GTGACTATTCTGAAGTGCTGGACATGCAAGGGAGTCCAGAAATCACAGATATGACCAACAGTATCAATGATCTTTCAGAG
GTCATTCGACTGACACATGAAAACCTTGAGCAAGAAACAAAACGCCTTTCCAGTATCCTGTCCTATATGACAGATGGCGT
GCTTGCGACCAACCGTCGGGGGCAGATTATCACTATCAACGATATGGCAACCAAGCAGTTGGGAGTTAAGAGAGATGAGG
TCCAAAATATGAGTATTTTGGATCTGCTTTCGATTTCAGACGAGTATGATTTGAGGGACCTGATTACCAATGTTCCTGAG
CTGACGATAGATTCTCAGGATGAAAATGGTGAGTACTTGAGCTTGCGGGTTCGCTTTGCCTTGGTAAGGCGGGAGTCGGG
CTTCATTTCTGGTTTGGTAGCTGTCTTGCATGATACGACCGAGCAGGACAAGGAAGAGCGGGAGCGTCGCCTCTTTGTCT
CCAACGTCAGCCACGAGTTGCGGACTCCGCTGACCAGTGTTAAGTCCTATCTGGAAGCCCTGGATGAGGGAGCCTTGTCT
GAGCCAGTAGCGCCAGACTTTGTCAAGGTATCACTCAATGAAACCAATCGCATGATGCGGATGGTGACGGACCTGCTTAG
TCTGTCCCGCATTGACAACGAGACTAGTCATCTGGAAGTGGAGCTGACGAATTTCACAGCTTTTATCACCTTTATCCTCA
ATCGCTTTGACAAGATAAAAAATCAAGACGAAACTAAGAAATATGAGATTATCCGTGATTATCCGATAACACCGATTTGG
GTGGAGATTGATACAGATAAGCTGACCCAGGTCATTGATAATATCATGAACAATGCCATCAAGTATTCACCAGATGGTGG
AACCATTACTGTTTCCATCAAGACAACAGATGAGCAGTTGATTCTCTCAATTGCAGATGAGGGACTGGGGATTCCCAAAC
AAGACCTGCCTAAGATCTTTGACCGCTTTTATCGAGTGGACAAGGCACGCAGCCGCGCACAGGGCGGAACGGGTCTGGGG
TTGGCCATTGCTAAGGAAATTATCAAGCAGCATCAGGGCTTTATCTGGGCTAAGAGTGAGTATGGTGTGGGCTCGACCTT
TACCATTGTCTTGCCTTATGAGAATGATGGTGTCCGGGATGACGACTGGGATAATGAAGATGATATATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

78.588

97.773

0.768
  vicK Streptococcus mutans UA159

70.72

89.755

0.635

Multiple sequence alignment