Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   DQM67_RS07535 Genome accession   NZ_LS483383
Coordinates   1496945..1498246 (-) Length   433 a.a.
NCBI ID   WP_005591893.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1491945..1503246
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS07520 (NCTC12479_01460) - 1492396..1495509 (-) 3114 WP_005591896.1 DEAD/DEAH box helicase -
  DQM67_RS07525 (NCTC12479_01461) hpf 1495659..1496201 (-) 543 WP_005591895.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQM67_RS07530 (NCTC12479_01462) comFC/cflB 1496283..1496948 (-) 666 WP_005591894.1 ComF family protein Machinery gene
  DQM67_RS07535 (NCTC12479_01463) comFA/cflA 1496945..1498246 (-) 1302 WP_005591893.1 DEAD/DEAH box helicase Machinery gene
  DQM67_RS07540 (NCTC12479_01464) - 1498303..1498938 (+) 636 WP_005591892.1 YigZ family protein -
  DQM67_RS07545 (NCTC12479_01465) cysK 1499055..1499984 (+) 930 WP_005591891.1 cysteine synthase A -
  DQM67_RS07550 (NCTC12479_01466) - 1500032..1500394 (-) 363 WP_005591890.1 S1 RNA-binding domain-containing protein -
  DQM67_RS07555 (NCTC12479_01467) - 1500394..1501794 (-) 1401 WP_037586248.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  DQM67_RS07560 (NCTC12479_01468) - 1501832..1502464 (-) 633 WP_005591888.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49713.73 Da        Isoelectric Point: 8.5968

>NTDB_id=1139516 DQM67_RS07535 WP_005591893.1 1496945..1498246(-) (comFA/cflA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MLEIKDCLGRIFTKDQLSPELRLQAQQMLSMREERRKLFCGCCGSKVDKENYQLPVNAYYCRECLILGRVRSDQELYYFP
QEAFPKNQVLKWQGQLTTFQEKVSQGLLESVAQKQNSLVHAVTGAGKTEMIYQVIAEVIDHGGAVCLASPRIDVCLELYR
RLQLDFACPISLLHGESEPYFRSPLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPVLYHAVEQSVKEKGTTIFLTATS
TDELDKKVQKGELKRLSLPRRFHGNPLIVPQKVWLADFQKYLAKKKLPPKLKKYIERQRKTGFPLLIFASEIKRGQEFAQ
VLEEIFPAERVGFVASTTENRLEIVEEFRKREITILVTTTILERGVTFPCVDVFVLEANHRLFSRSALVQISGRVGRSME
RPTGDLFFFHDGTTHSIEKAIREIKLMNKEAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=1139516 DQM67_RS07535 WP_005591893.1 1496945..1498246(-) (comFA/cflA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGTTAGAAATAAAAGATTGCCTAGGTAGGATATTTACAAAGGATCAGCTCAGCCCTGAGCTGCGCTTGCAGGCCCAGCA
GATGCTCAGTATGCGAGAGGAAAGGAGGAAATTATTTTGCGGCTGCTGTGGTTCTAAAGTGGACAAGGAGAACTACCAGC
TACCTGTCAATGCCTACTATTGTAGGGAATGTCTGATTTTGGGGCGAGTTCGGAGTGATCAAGAACTCTACTATTTTCCA
CAGGAAGCTTTTCCTAAAAATCAGGTACTCAAGTGGCAGGGACAATTAACGACCTTTCAAGAGAAAGTTTCTCAGGGACT
GTTAGAGTCAGTTGCTCAAAAGCAGAATAGCCTAGTCCATGCAGTGACTGGGGCGGGCAAAACGGAAATGATTTATCAGG
TGATTGCAGAAGTGATTGACCATGGAGGTGCCGTTTGTCTAGCCAGCCCTCGGATTGATGTCTGTTTGGAGCTTTATCGC
CGGCTCCAGCTGGATTTTGCCTGTCCTATTTCACTTTTGCATGGTGAATCCGAGCCATATTTTCGCAGTCCCTTGGTCAT
TGCCACTACCCATCAGCTCCTCAAATTTTATCGAGCTTTTGATTTGTTGATTGTGGATGAAGTAGATGCTTTTCCTTATG
TGGACAATCCTGTGCTCTACCATGCCGTGGAGCAGTCGGTCAAGGAGAAGGGAACGACAATTTTCTTAACTGCCACTTCG
ACGGATGAGCTGGATAAAAAAGTCCAAAAAGGAGAATTAAAACGCCTTAGTCTTCCTCGGCGCTTCCATGGGAATCCTTT
GATTGTGCCCCAAAAAGTTTGGCTGGCAGATTTTCAAAAATATTTGGCGAAAAAGAAATTGCCGCCTAAACTGAAAAAAT
ATATCGAGAGACAGAGAAAAACAGGCTTTCCCTTACTGATCTTTGCCTCGGAAATCAAAAGAGGTCAAGAATTTGCGCAA
GTTTTGGAGGAGATATTTCCAGCGGAAAGAGTCGGATTTGTGGCTTCGACAACTGAAAATCGTCTAGAAATCGTTGAAGA
GTTTCGCAAACGAGAAATTACTATTCTAGTCACGACGACCATCCTAGAGCGTGGTGTGACCTTTCCCTGTGTAGATGTCT
TTGTTCTGGAAGCCAACCATCGCCTCTTTAGTCGTAGCGCCTTGGTTCAGATTTCTGGCCGAGTGGGACGTAGTATGGAG
AGGCCAACGGGAGATTTATTCTTCTTTCACGATGGTACCACACATTCAATCGAAAAAGCGATTCGTGAAATCAAACTGAT
GAACAAGGAGGCCGGCCTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(293-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

72.535

98.383

0.714
  comFA/cflA Streptococcus pneumoniae D39

71.729

98.845

0.709
  comFA/cflA Streptococcus pneumoniae R6

71.729

98.845

0.709
  comFA/cflA Streptococcus pneumoniae TIGR4

71.729

98.845

0.709
  comFA/cflA Streptococcus pneumoniae Rx1

71.729

98.845

0.709
  comFA/cflA Streptococcus mitis SK321

71.596

98.383

0.704
  comFA Lactococcus lactis subsp. cremoris KW2

53.333

96.998

0.517
  comFA Latilactobacillus sakei subsp. sakei 23K

42.105

92.148

0.388
  comFA Bacillus subtilis subsp. subtilis str. 168

39.173

94.919

0.372

Multiple sequence alignment