Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQM69_RS04275 Genome accession   NZ_LS483381
Coordinates   884384..885769 (+) Length   461 a.a.
NCBI ID   WP_019769637.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NCTC10921     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 879384..890769
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM69_RS04260 (NCTC10921_00838) phoU 880152..880805 (+) 654 WP_002961527.1 phosphate signaling complex protein PhoU -
  DQM69_RS04265 (NCTC10921_00839) - 880912..883455 (+) 2544 WP_109982554.1 M1 family metallopeptidase -
  DQM69_RS04270 (NCTC10921_00840) ciaR 883720..884394 (+) 675 WP_002961524.1 response regulator transcription factor Regulator
  DQM69_RS04275 (NCTC10921_00841) ciaH 884384..885769 (+) 1386 WP_019769637.1 sensor histidine kinase Regulator
  DQM69_RS04280 (NCTC10921_00842) rpsT 885884..886132 (-) 249 WP_019772096.1 30S ribosomal protein S20 -
  DQM69_RS04285 (NCTC10921_00843) coaA 886185..887105 (-) 921 WP_002961520.1 type I pantothenate kinase -
  DQM69_RS04290 (NCTC10921_00844) - 887170..887760 (+) 591 WP_019777495.1 class I SAM-dependent methyltransferase -
  DQM69_RS04295 (NCTC10921_00845) - 887757..889034 (+) 1278 WP_019785613.1 pyrimidine-nucleoside phosphorylase -
  DQM69_RS04300 (NCTC10921_00846) deoC 889042..889704 (+) 663 WP_019770389.1 deoxyribose-phosphate aldolase -
  DQM69_RS04305 (NCTC10921_00847) - 889691..890110 (+) 420 WP_019770119.1 cytidine deaminase -

Sequence

Protein


Download         Length: 461 a.a.        Molecular weight: 51969.24 Da        Isoelectric Point: 6.1942

>NTDB_id=1139393 DQM69_RS04275 WP_019769637.1 884384..885769(+) (ciaH) [Streptococcus sobrinus strain NCTC10921]
MLNKLKKRIFSEGFSTFLHFLSVFTVIFLVMTILILQIMRIGIYSSVDDNLNKAVDSVDSYIYMNMYRASLYSAFGGKNN
SDLSVLTDGDEFLGNGTTLPGNANSTVNQSPNKSHVELNATIETIIYDKNGKVLNSSEIFSGLNKLKIDKSELGEVNEVS
VNGSFREKEHYRYKTVSVSDKQFPKVAYVTIAISVNQLDSANSRYQIIIITVMIIFWLLSVFASVYLANWSRKPILESYE
KQKNFVEDASHELRTPLTVLQNRLESLFRKPDETILDNYETVASSLEEVRNMRILTTNLLNLARRDDKLNPEIEEIEPNF
FDNIFENYSLIAEESGKVLSCSNQLRTSIKSDKTLIKQVMTILFDNAVKYTGDDGAIRIIVSNSDRKLVITVADNGSGIS
EEDKSKIFDRFYRIDKARTRQTGGFGLGLSLAKQIVEALKGTIAVRDNTPTGTVFEIKLNT

Nucleotide


Download         Length: 1386 bp        

>NTDB_id=1139393 DQM69_RS04275 WP_019769637.1 884384..885769(+) (ciaH) [Streptococcus sobrinus strain NCTC10921]
ATGTTAAATAAGTTAAAGAAGAGGATCTTTTCTGAAGGGTTCTCGACTTTTCTTCACTTCCTATCCGTTTTCACTGTTAT
TTTCCTAGTGATGACCATTCTGATTTTGCAAATTATGCGGATTGGAATCTACTCATCGGTTGACGATAATCTCAACAAGG
CTGTAGATAGTGTTGATTCTTATATCTACATGAATATGTACAGAGCTAGCCTTTATTCAGCCTTTGGCGGAAAAAATAAT
TCTGATTTATCTGTTCTAACCGATGGTGATGAATTTTTAGGAAACGGGACAACTTTGCCTGGTAATGCTAATTCAACGGT
GAATCAAAGTCCAAATAAATCTCATGTTGAATTGAATGCAACTATTGAAACCATTATATATGACAAGAATGGTAAGGTAC
TTAATAGCTCGGAAATATTTTCTGGTCTTAATAAGCTGAAAATTGATAAGAGTGAGCTAGGCGAGGTTAACGAGGTTAGT
GTTAACGGTAGCTTTCGTGAAAAGGAGCATTATCGGTATAAGACTGTCTCGGTGTCGGACAAGCAATTCCCAAAGGTTGC
TTATGTGACGATTGCTATTAGTGTTAACCAATTAGATAGTGCCAATTCTCGCTATCAAATTATTATCATTACGGTTATGA
TTATTTTCTGGCTCTTATCTGTCTTTGCCAGTGTTTATCTGGCTAATTGGTCGCGTAAGCCAATTCTTGAAAGTTATGAG
AAACAGAAGAATTTTGTAGAAGATGCCAGTCATGAGTTGAGGACGCCTCTAACGGTTCTCCAAAATCGTTTGGAAAGTCT
TTTTCGTAAGCCTGATGAGACCATTTTGGATAATTACGAGACTGTCGCCTCTAGTTTGGAAGAAGTTCGGAATATGCGGA
TTTTAACCACGAATCTTTTGAATCTGGCTAGACGTGATGACAAACTTAATCCAGAAATTGAAGAAATTGAACCTAATTTC
TTCGACAATATTTTTGAGAATTATAGTTTAATTGCTGAGGAAAGTGGCAAAGTCCTATCTTGTAGCAACCAATTAAGGAC
CTCAATCAAGTCGGATAAGACCTTGATTAAACAAGTTATGACTATCCTTTTTGATAATGCTGTTAAGTATACTGGAGATG
ACGGTGCTATAAGGATTATTGTTTCCAATAGTGATAGAAAGCTGGTTATTACTGTTGCGGATAATGGTTCGGGAATCAGT
GAAGAAGACAAATCGAAAATTTTCGATCGATTTTATCGGATTGACAAGGCGCGAACCCGGCAGACTGGTGGTTTTGGTCT
AGGACTATCCTTAGCTAAGCAGATTGTTGAAGCTTTGAAGGGGACTATTGCTGTTCGAGATAACACACCCACGGGTACTG
TTTTTGAAATTAAATTAAATACTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(352-459)

His Kinase A (phospho-acceptor) domain (HisKA)

(242-306)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

54.031

99.566

0.538
  ciaH Streptococcus pneumoniae Rx1

48.06

100

0.484
  ciaH Streptococcus pneumoniae D39

48.06

100

0.484
  ciaH Streptococcus pneumoniae R6

48.06

100

0.484
  ciaH Streptococcus pneumoniae TIGR4

48.06

100

0.484

Multiple sequence alignment