Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQM54_RS05275 Genome accession   NZ_LS483375
Coordinates   1073002..1074408 (+) Length   468 a.a.
NCBI ID   WP_111723686.1    Uniprot ID   -
Organism   Streptococcus gordonii strain NCTC3165     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 1068002..1079408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM54_RS05250 (NCTC3165_01045) - 1070129..1070413 (+) 285 WP_045634874.1 helix-turn-helix domain-containing protein -
  DQM54_RS05255 (NCTC3165_01046) - 1070464..1070790 (+) 327 WP_083277171.1 DMT family transporter -
  DQM54_RS05260 (NCTC3165_01047) - 1070805..1071608 (+) 804 WP_045634872.1 SDR family NAD(P)-dependent oxidoreductase -
  DQM54_RS05265 (NCTC3165_01048) - 1071792..1072208 (+) 417 WP_111723685.1 hypothetical protein -
  DQM54_RS05270 (NCTC3165_01049) ciaR 1072338..1073012 (+) 675 WP_008808730.1 response regulator transcription factor Regulator
  DQM54_RS05275 (NCTC3165_01050) ciaH 1073002..1074408 (+) 1407 WP_111723686.1 sensor histidine kinase Regulator
  DQM54_RS05280 (NCTC3165_01051) - 1074556..1076007 (-) 1452 WP_172455829.1 alpha-amylase -
  DQM54_RS05285 (NCTC3165_01052) - 1076123..1076632 (-) 510 WP_008808727.1 DNA topology modulation protein -
  DQM54_RS05290 (NCTC3165_01053) rpsT 1076697..1076945 (-) 249 WP_008808726.1 30S ribosomal protein S20 -
  DQM54_RS05295 (NCTC3165_01054) coaA 1077042..1077962 (-) 921 WP_105165144.1 type I pantothenate kinase -
  DQM54_RS05300 (NCTC3165_01055) - 1078068..1078661 (+) 594 WP_111723688.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 468 a.a.        Molecular weight: 53330.33 Da        Isoelectric Point: 9.1193

>NTDB_id=1139118 DQM54_RS05275 WP_111723686.1 1073002..1074408(+) (ciaH) [Streptococcus gordonii strain NCTC3165]
MLNKLRRTFYADDFSYFIRYFGVFTLIFSAMTLLIIQIMRSGLYTTVDDNLKSLSQNPRSVLHLALARAANMQPTIDEGQ
SSDDVSGPQDAPDPGPMDNLKVNSNTEAVLFDEDLKPLTTADHFLSLKKISIKKKDVGKIIQTTLKNNYGQEELYRMLVF
EINPSEFLSGNLLNKVKYAAVLINVNQLEQTSQNHEQIIVIVMISFWLISIIASIYLARVSVKPLMDSMQKQKSFVENAS
HELRTPLAVLQNRLETLFRKPEATIMESSENIASSLEEVRNMRMLTTNLLNLARRDDGIKAEIAEVEPEFFTTTFANYEI
IADENEKVFIYENHIDHNIKTDRTLLKQLMTILFDNAVKYTEEDGIIKFIVWSKDRSLYLRVSDNGPGINNEDKKKIFDR
FYRVDKARTRQKGGFGLGLSLAKQIADALKGTITVKDNRPKGTIFEVKISIKSESKKRVGRLSDGKKD

Nucleotide


Download         Length: 1407 bp        

>NTDB_id=1139118 DQM54_RS05275 WP_111723686.1 1073002..1074408(+) (ciaH) [Streptococcus gordonii strain NCTC3165]
ATGCTGAATAAACTTAGACGAACTTTTTATGCGGATGATTTTTCATATTTCATTCGCTATTTTGGTGTATTCACACTGAT
TTTCTCGGCCATGACTCTTTTAATCATTCAGATTATGCGCTCAGGACTCTATACAACCGTTGACGATAATTTAAAAAGTT
TAAGTCAGAATCCCAGATCTGTTCTCCACCTTGCTTTGGCTCGTGCAGCCAATATGCAACCGACGATTGATGAAGGTCAG
TCATCTGATGATGTATCTGGACCACAAGACGCACCAGACCCTGGACCAATGGATAATCTGAAGGTGAATTCGAACACTGA
AGCTGTCTTGTTTGATGAAGACTTGAAACCATTGACTACTGCAGATCATTTTCTTAGTTTAAAAAAGATTTCAATCAAGA
AAAAGGATGTAGGTAAAATTATTCAGACTACTTTGAAAAACAACTATGGTCAAGAAGAACTCTATCGTATGTTGGTTTTT
GAGATTAATCCAAGCGAATTCTTATCTGGGAATCTTTTGAACAAAGTTAAATATGCAGCAGTCCTGATTAATGTCAATCA
GTTGGAGCAAACCAGTCAGAATCATGAACAGATTATTGTCATTGTTATGATTAGCTTTTGGTTAATCTCAATTATTGCTA
GTATCTATTTGGCTCGTGTCAGTGTGAAGCCTCTGATGGACAGTATGCAGAAACAAAAATCTTTTGTTGAAAATGCAAGC
CATGAGTTGCGTACTCCTTTAGCTGTTTTGCAAAACCGCTTGGAAACTCTTTTCCGAAAACCCGAAGCTACCATTATGGA
ATCAAGCGAAAATATTGCCTCCAGTCTGGAAGAAGTTCGGAATATGCGGATGCTAACAACTAATCTATTGAATCTTGCAA
GAAGAGATGATGGCATTAAGGCTGAAATTGCTGAAGTTGAACCAGAATTTTTCACTACAACATTTGCCAACTATGAAATC
ATTGCGGATGAAAATGAGAAAGTATTTATCTACGAAAATCATATCGACCACAACATCAAGACAGATAGAACACTTCTAAA
ACAGCTGATGACCATTCTCTTTGATAATGCTGTGAAATATACAGAAGAAGATGGGATCATTAAGTTTATAGTATGGTCAA
AAGACCGTTCTCTTTACTTACGAGTGTCCGATAACGGCCCTGGAATCAATAATGAAGACAAAAAGAAAATTTTTGATCGT
TTTTATAGAGTTGATAAGGCCAGAACAAGACAAAAGGGTGGTTTTGGTCTAGGTCTATCTCTCGCAAAACAAATAGCCGA
TGCTCTAAAGGGTACAATTACTGTTAAGGACAATAGACCTAAAGGTACCATTTTTGAGGTCAAAATTTCCATCAAATCAG
AAAGTAAGAAACGAGTTGGACGATTGAGTGATGGAAAAAAAGATTGA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(342-449)

His Kinase A (phospho-acceptor) domain (HisKA)

(233-298)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

66.157

97.863

0.647
  ciaH Streptococcus pneumoniae D39

66.157

97.863

0.647
  ciaH Streptococcus pneumoniae R6

66.157

97.863

0.647
  ciaH Streptococcus pneumoniae TIGR4

66.157

97.863

0.647
  ciaH Streptococcus mutans UA159

54.343

95.94

0.521

Multiple sequence alignment