Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   DQM66_RS10755 Genome accession   NZ_LS483374
Coordinates   2013255..2013917 (-) Length   220 a.a.
NCBI ID   WP_000649974.1    Uniprot ID   A0A0F7YBW3
Organism   Streptococcus pneumoniae strain NCTC7466     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2008255..2018917
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM66_RS10730 (NCTC7466_02060) - 2008405..2008671 (-) 267 WP_001278167.1 Veg family protein -
  DQM66_RS10735 (NCTC7466_02061) dnaB 2008673..2010025 (-) 1353 WP_000852486.1 replicative DNA helicase -
  DQM66_RS10740 (NCTC7466_02062) rplI 2010069..2010521 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  DQM66_RS10745 (NCTC7466_02063) - 2010518..2012491 (-) 1974 WP_000715109.1 DHH family phosphoesterase -
  DQM66_RS10750 (NCTC7466_02064) hpf 2012627..2013175 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  DQM66_RS10755 (NCTC7466_02065) comFC/cflB 2013255..2013917 (-) 663 WP_000649974.1 ComF family protein Machinery gene
  DQM66_RS10760 (NCTC7466_02066) comFA/cflA 2013914..2015212 (-) 1299 WP_000867601.1 DEAD/DEAH box helicase Machinery gene
  DQM66_RS10765 (NCTC7466_02067) - 2015268..2015903 (+) 636 WP_000395739.1 YigZ family protein -
  DQM66_RS10770 (NCTC7466_02068) cysK 2016188..2017108 (+) 921 WP_000029860.1 cysteine synthase A -
  DQM66_RS10780 - 2017347..2017697 (-) 351 Protein_1998 IS66 family transposase -
  DQM66_RS10785 - 2017697..2017968 (+) 272 Protein_1999 transposase -
  DQM66_RS10790 (NCTC7466_02069) tnpB 2018159..2018446 (-) 288 WP_000973412.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25169.03 Da        Isoelectric Point: 7.7116

>NTDB_id=1139089 DQM66_RS10755 WP_000649974.1 2013255..2013917(-) (comFC/cflB) [Streptococcus pneumoniae strain NCTC7466]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1139089 DQM66_RS10755 WP_000649974.1 2013255..2013917(-) (comFC/cflB) [Streptococcus pneumoniae strain NCTC7466]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAGTTGGAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTAGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCCGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F7YBW3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae Rx1

100

100

1
  comFC/cflB Streptococcus pneumoniae D39

100

100

1
  comFC/cflB Streptococcus pneumoniae R6

100

100

1
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus mitis NCTC 12261

91.364

100

0.914
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment