Detailed information NTG1138932

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: DQM57_RS00230
• Genome accession: NZ_LS483369
• Coordinates: 40332..41192 (-)
• Length: 286 a.a.
• NCBI ID: WP_111726191.1
• Uniprot ID: A0A7T3ESH3
• Organism: Neisseria cinerea strain NCTC10294
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 35332..46192

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM57_RS00195 (NCTC10294_00038)	rplU	35421..35729 (-)	309	WP_002216394.1	50S ribosomal protein L21	-
DQM57_RS00200 (NCTC10294_00039)	-	35952..36926 (+)	975	WP_108043479.1	polyprenyl synthetase family protein	-
DQM57_RS00205 (NCTC10294_00040)	-	36931..37377 (+)	447	WP_003676595.1	DUF441 domain-containing protein	-
DQM57_RS00215 (NCTC10294_00042)	pilF	37727..39403 (+)	1677	WP_108043478.1	type IV-A pilus assembly ATPase PilB	Machinery gene
DQM57_RS00220 (NCTC10294_00043)	-	39496..39705 (-)	210	WP_039854241.1	DNA gyrase inhibitor YacG	-
DQM57_RS00225 (NCTC10294_00044)	coaE	39698..40330 (-)	633	WP_111726190.1	dephospho-CoA kinase	-
DQM57_RS00230 (NCTC10294_00045)	pilD	40332..41192 (-)	861	WP_111726191.1	A24 family peptidase	Machinery gene
DQM57_RS00235 (NCTC10294_00046)	pilG	41266..42498 (-)	1233	WP_107996268.1	type II secretion system F family protein	Machinery gene
DQM57_RS00240 (NCTC10294_00047)	pgi	42856..44499 (+)	1644	WP_111726193.1	glucose-6-phosphate isomerase	-
DQM57_RS00245 (NCTC10294_00048)	dapD	44709..45530 (+)	822	WP_003676582.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31256.25 Da
• Isoelectric Point: 8.4715

>NTDB_id=1138932 DQM57_RS00230 WP_111726191.1 40332..41192(-) (pilD) [Neisseria cinerea strain NCTC10294]
MSDLSILSAFVVPLAAVFGLLVGSFLNVVIYRIPVMMERGWTVFAKEHLNLPLTDEESHTFNLMKPDSCCPKCRAPVRAW
QNIPIVSYLFLRGKCASCRTKISIRYPLIELLTGILFGLVAWQYGWSWITLGGLILTAFLISLTLIDADTQYLPDSMTLP
LIWLGLLFNFNGDFVSLQSAVSGAVAGYGSLWLLCAVYKLLTGKIGMGNGDFKLLAALGAWLGISVLPVLVFLAALVGLA
MAVIMRISKGQYFAFGPALAISGWIIFAANDSVLRAVNWWLTHSGL

Nucleotide

• Length: 861 bp

>NTDB_id=1138932 DQM57_RS00230 WP_111726191.1 40332..41192(-) (pilD) [Neisseria cinerea strain NCTC10294]
ATGTCTGATTTGTCTATATTGTCGGCATTTGTCGTACCGTTGGCAGCGGTGTTCGGGCTGCTGGTTGGAAGTTTCTTAAA
CGTCGTCATTTACCGCATACCGGTCATGATGGAGCGCGGTTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGATGAGGAAAGCCATACCTTCAACCTGATGAAACCGGATTCCTGTTGCCCGAAATGTCGCGCACCGGTACGCGCATGG
CAGAATATTCCGATTGTCAGCTACCTATTCCTGCGCGGAAAATGTGCCTCCTGCCGAACCAAAATCAGCATACGCTATCC
CTTAATCGAACTGCTGACCGGCATATTGTTCGGCCTGGTCGCATGGCAATACGGCTGGTCTTGGATTACACTGGGCGGTT
TGATACTGACCGCATTTTTGATTTCCCTTACCCTCATCGATGCAGATACCCAATATCTGCCCGATTCAATGACCCTACCC
TTAATTTGGCTGGGGCTGCTGTTCAACTTTAACGGGGATTTCGTGTCTTTACAATCGGCGGTTTCAGGCGCGGTTGCCGG
CTACGGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTTACAGGAAAAATCGGCATGGGTAACGGCGACTTCAAAC
TGCTTGCCGCATTAGGGGCGTGGCTCGGCATATCCGTACTACCCGTTCTGGTATTCCTTGCCGCACTGGTCGGCTTGGCA
ATGGCAGTCATCATGCGCATCTCCAAAGGGCAATATTTTGCCTTCGGTCCCGCACTGGCAATCTCAGGCTGGATTATCTT
CGCAGCAAACGATTCCGTACTTCGTGCGGTTAATTGGTGGCTTACCCATTCGGGACTGTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

3D structure

• AlphaFold DB: A0A7T3ESH3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	85.866	98.951	0.85
pilD	Acinetobacter baumannii D1279779	46.619	98.252	0.458
pilD	Vibrio cholerae strain A1552	47.636	96.154	0.458
pilD	Vibrio campbellii strain DS40M4	46.403	97.203	0.451
pilD	Acinetobacter nosocomialis M2	48.485	92.308	0.448