Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   DQM52_RS05595 Genome accession   NZ_LS483367
Coordinates   1087354..1088664 (-) Length   436 a.a.
NCBI ID   WP_014612303.1    Uniprot ID   A0A9X8T438
Organism   Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1082354..1093664
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM52_RS05565 (NCTC5371_01137) - 1082789..1083178 (-) 390 WP_003058840.1 cytidine deaminase -
  DQM52_RS05570 (NCTC5371_01138) deoC 1083165..1083827 (-) 663 WP_111681721.1 deoxyribose-phosphate aldolase -
  DQM52_RS05575 (NCTC5371_01139) - 1083843..1085120 (-) 1278 WP_111681722.1 pyrimidine-nucleoside phosphorylase -
  DQM52_RS05580 (NCTC5371_01140) - 1085107..1085706 (-) 600 WP_015057597.1 class I SAM-dependent methyltransferase -
  DQM52_RS05585 (NCTC5371_01141) coaA 1085974..1086894 (+) 921 WP_110408128.1 type I pantothenate kinase -
  DQM52_RS05590 (NCTC5371_01142) rpsT 1086948..1087196 (+) 249 WP_009881183.1 30S ribosomal protein S20 -
  DQM52_RS05595 (NCTC5371_01143) ciaH 1087354..1088664 (-) 1311 WP_014612303.1 HAMP domain-containing sensor histidine kinase Regulator
  DQM52_RS05600 (NCTC5371_01144) ciaR 1088657..1089331 (-) 675 WP_014612304.1 response regulator transcription factor Regulator
  DQM52_RS05605 (NCTC5371_01145) - 1089535..1092072 (-) 2538 WP_084916834.1 M1 family metallopeptidase -
  DQM52_RS05610 (NCTC5371_01146) phoU 1092273..1092926 (-) 654 WP_003057760.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49918.49 Da        Isoelectric Point: 8.2375

>NTDB_id=1138847 DQM52_RS05595 WP_014612303.1 1087354..1088664(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
MNKLKKEVFSDQYTHFFHFFAVFTGIFVVMTIIILQIMRFGVYSSIDSSLISVSNNASSYANRTMARISSFYFDAENNVI
KPLPDSDNSKLVGTPAANTDIILFSANGTILNSFDAFSNYQNFHLDKRQLGTIVTTSLINFYGQEEKYHTITVRVHIRNY
PAVAYMMAVVNVEQLDSANERYEQIIIIVMIIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDATFFDAIFENYQLVAEENGKVFLFEN
QVNRILRMDKALLKQLMTILFDNAIKYTDKEGVVDIKVKTTEKNLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVISLKGSISVKDNLPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=1138847 DQM52_RS05595 WP_014612303.1 1087354..1088664(-) (ciaH) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5371]
ATGAATAAATTAAAAAAAGAAGTCTTCTCTGACCAATACACCCATTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTTGTGATGACCATCATTATTTTGCAGATTATGCGATTTGGTGTGTATTCTTCTATCGATAGTAGTCTGATTTCTGTTA
GTAATAATGCAAGCAGTTATGCCAATCGTACTATGGCTAGAATATCCTCTTTTTACTTTGATGCAGAAAATAATGTCATT
AAACCTTTGCCTGATTCAGATAATTCAAAGCTAGTAGGAACACCGGCGGCAAACACAGATATTATCCTATTTAGTGCCAA
TGGCACAATTTTGAATTCCTTTGATGCTTTCTCCAATTATCAAAATTTTCATTTAGACAAGCGACAATTAGGGACGATTG
TTACTACTAGCCTGATTAATTTTTACGGTCAAGAGGAGAAGTATCATACCATAACAGTAAGGGTTCATATCAGAAATTAC
CCAGCTGTGGCATATATGATGGCAGTTGTCAACGTCGAGCAGTTGGACAGTGCCAACGAACGCTACGAACAAATTATTAT
CATTGTGATGATCATCTTCTGGTTAATTTCTATTTTGGCAAGTATTTATTTGTCCAAGTGGAGCCGAAAGCCGATTTTGG
AAAGTTATGAAAAACAAAAAATGTTTGTGGAAAATGCTAGTCATGAATTAAGAACCCCATTGGCTGTTTTGCAAAATCGC
TTAGAGTCTCTTTTCCGGAAGCCTAATGAAACCATATTGGAAAATAGTGAACATTTGGCTTCAAGTCTAGATGAAGTTCG
AAATATGCGTATTTTAACAACTAATCTCTTAAATTTAGCAAGACGTGATGATGGGATCAACCCTCAGTGGACTGACTTAG
ACGCTACCTTTTTTGATGCTATTTTTGAGAATTATCAGCTAGTTGCTGAAGAAAATGGCAAGGTATTTCTTTTCGAAAAT
CAAGTTAACCGCATCTTGAGAATGGACAAGGCTCTTTTGAAACAATTGATGACGATTTTATTTGATAATGCGATCAAATA
CACGGATAAAGAAGGCGTTGTTGACATTAAGGTCAAGACAACAGAGAAAAATCTCTTGATTTCAGTCATTGATAACGGTC
CAGGAATTAAAGATGAGGAAAAGAAAAAGATTTTTGACCGTTTTTATCGCGTTGATAAAGCTAGAACCCGTCAGACTGGA
GGCTTTGGCTTAGGCTTGGCCTTAGCTCAACAGATTGTGATATCACTCAAAGGAAGTATCAGCGTTAAGGATAACCTTCC
TAAGGGTAGTATCTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.895

100

0.58
  ciaH Streptococcus pneumoniae Rx1

51.142

100

0.514
  ciaH Streptococcus pneumoniae D39

51.142

100

0.514
  ciaH Streptococcus pneumoniae R6

51.142

100

0.514
  ciaH Streptococcus pneumoniae TIGR4

51.142

100

0.514

Multiple sequence alignment