Detailed information NTG1138790

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: DQM60_RS08015
• Genome accession: NZ_LS483366
• Coordinates: 1731006..1733246 (-)
• Length: 746 a.a.
• NCBI ID: WP_084870985.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain NCTC7366
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1726006..1738246

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM60_RS07995 (NCTC7366_01611)	-	1726874..1727734 (-)	861	WP_004183173.1	methionyl aminopeptidase	-
DQM60_RS08000 (NCTC7366_01612)	spxR	1727774..1729054 (-)	1281	WP_002884454.1	CBS-HotDog domain-containing transcription factor SpxR	-
DQM60_RS08005 (NCTC7366_01613)	-	1729047..1729592 (-)	546	WP_084870984.1	GNAT family N-acetyltransferase	-
DQM60_RS08010 (NCTC7366_01614)	-	1729658..1730920 (-)	1263	WP_013991032.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
DQM60_RS08015 (NCTC7366_01615)	comEC/celB	1731006..1733246 (-)	2241	WP_084870985.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
DQM60_RS08020 (NCTC7366_01616)	comEA	1733236..1733934 (-)	699	WP_111686659.1	helix-hairpin-helix domain-containing protein	Machinery gene
DQM60_RS08025 (NCTC7366_01617)	-	1734042..1734797 (-)	756	WP_013991035.1	lysophospholipid acyltransferase family protein	-
DQM60_RS08030 (NCTC7366_01618)	-	1734927..1735862 (+)	936	WP_045002039.1	polysaccharide deacetylase family protein	-
DQM60_RS08035 (NCTC7366_01619)	-	1735912..1736676 (+)	765	WP_013991037.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
DQM60_RS08040 (NCTC7366_01620)	-	1736680..1736949 (+)	270	WP_084870988.1	GIY-YIG nuclease family protein	-
DQM60_RS08045 (NCTC7366_01621)	-	1737041..1737427 (-)	387	WP_002886743.1	IS110 family transposase	-
DQM60_RS08050 (NCTC7366_01622)	-	1737447..1738208 (-)	762	WP_002886742.1	IS110 family transposase	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84558.53 Da
• Isoelectric Point: 9.9425

>NTDB_id=1138790 DQM60_RS08015 WP_084870985.1 1731006..1733246(-) (comEC/celB) [Streptococcus salivarius strain NCTC7366]
MWLKKAPINLFSLALLIAALYFTIFVTNVYAMGAFAFLLVCFLKHHWKNKAALKLVGLVGGFFLIYFLFLHHRASIQDKQ
APAEINQVTLVADTLSVNGEQLSAIGKAKGQTYQVFYRLKYEKEQHFFKTTSQTLVLKGKIKLSPATGQRNFQGFNYQSY
LASQGIYRMAQIEHLDHVVPQKSLSPLAFFHQLRRRALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKDYLLIILLPFSLCYGLMTGWTASVLRSLIQSLLAEFGIKKLDNMGITLLLLFLF
LPHFLLTVGGVLSCSYAFLLCLFDFEEMSSLKKSICTSLVLSLGILPFLTYYYGTFQPVSLILTAMFSIVFDSFLLPVLT
VFFVLSGLVIFSQINPLFEWMETFLTWIQSWIGQPLILGKPSLFQFGLMIAVLVMLFDFWKKPQFRVCLLMIFSLLMVWV
KHPLTNEVTMVDVGQGDSIFLRSMKGDTILIDVGGKVTFGSKEKWQEASQTSNAEKALIPYLQARGVSQIDHLVLTHTDT
DHIGDLEEVTKRFKIKEICVSQGALTKPSFVKRLRTLKRPVRTLKAGDNLPMMGSKLQVLYPNKIGDGGNNDSIVLYGKL
LGSSFLFTGDLEKEGEEELMVSYPNLKASVLKAGHHGSKGSSSEAFLDQLHPSLALVSAGENNRYKHPNDETLKRFKKRH
IKVLRTDQNGAIRFKGWFKWSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1138790 DQM60_RS08015 WP_084870985.1 1731006..1733246(-) (comEC/celB) [Streptococcus salivarius strain NCTC7366]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCTTGGCTCTGTTAATAGCTGCTCTTTATTTTACGATTTTTGTCAC
TAATGTTTATGCTATGGGGGCTTTTGCTTTTCTTTTAGTATGTTTTTTGAAGCATCATTGGAAGAATAAGGCAGCCCTAA
AGTTGGTGGGGCTTGTAGGTGGGTTCTTTTTGATTTATTTTTTATTCTTGCATCACAGAGCTAGCATACAAGATAAACAA
GCTCCTGCTGAAATCAATCAGGTGACTCTGGTTGCTGATACGCTATCGGTTAATGGTGAGCAATTATCAGCTATTGGAAA
GGCAAAGGGACAAACTTATCAGGTCTTTTACCGACTCAAATATGAGAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTAGTACTAAAAGGAAAAATAAAGTTATCCCCAGCAACTGGTCAACGTAATTTTCAAGGGTTTAATTATCAGTCTTAT
CTAGCCAGTCAAGGCATTTATCGAATGGCTCAGATTGAGCACTTGGACCATGTGGTGCCTCAAAAATCTCTATCTCCCCT
AGCTTTTTTCCATCAACTGAGGAGGAGGGCATTGGTTCATATCCAGACGCACTTTCCTAATCCTATGAGACACTATATGA
CAGGCCTGCTCTTTGGGTATTTGGATAAGGAGTTTGATGAGCAGAGTCAGCTTTACACAAGCTTAGGTATTATTCATCTA
TTCGCACTTTCAGGGATGCAAGTCGGCTTTTTTCTGGGATGGTTTCGCTATGGACTCCTACGCTTGGGCCTTCCTAAAGA
TTATCTATTAATTATCTTGCTGCCTTTTTCCTTATGCTATGGCTTAATGACAGGTTGGACAGCTTCAGTCCTACGTTCCT
TGATTCAAAGTTTGTTGGCGGAGTTTGGTATTAAAAAACTGGATAATATGGGTATAACCTTGCTTTTATTGTTTCTCTTT
TTACCTCATTTTCTTTTGACAGTGGGAGGTGTTTTAAGTTGTTCCTATGCCTTCTTGTTGTGTTTGTTTGATTTTGAGGA
GATGTCATCTCTTAAAAAGTCAATCTGTACGAGCTTGGTATTGAGTCTTGGGATTTTGCCCTTTCTAACTTACTATTATG
GGACCTTTCAACCGGTGAGTTTAATTCTGACGGCGATGTTTTCGATAGTCTTTGATAGCTTTCTCTTACCTGTCTTGACG
GTCTTCTTTGTCCTTTCAGGACTAGTAATCTTTTCTCAAATCAACCCACTTTTTGAATGGATGGAGACCTTTTTGACTTG
GATACAATCCTGGATAGGCCAGCCTTTGATTTTAGGGAAACCTAGTTTGTTTCAGTTTGGCTTGATGATAGCTGTATTGG
TTATGCTCTTTGATTTTTGGAAAAAGCCCCAGTTTAGGGTTTGTCTTTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAACCAATGAGGTGACTATGGTTGACGTTGGTCAGGGAGATAGTATTTTTCTGAGGAGTATGAAAGGCGA
TACCATCCTAATTGATGTGGGTGGCAAGGTGACTTTCGGCTCAAAGGAAAAATGGCAAGAGGCTAGTCAGACGAGCAATG
CGGAGAAAGCCTTGATTCCCTATCTACAGGCTAGGGGAGTGTCTCAAATTGACCATCTGGTCCTGACTCATACGGACACA
GACCATATTGGTGATTTGGAAGAAGTGACCAAGCGGTTTAAGATTAAGGAAATCTGTGTCAGTCAAGGAGCTTTGACTAA
GCCTAGTTTTGTGAAACGACTTCGAACTTTAAAACGCCCAGTTCGCACTCTAAAGGCTGGAGACAACTTACCCATGATGG
GAAGTAAGCTACAGGTTCTTTATCCAAATAAAATTGGTGATGGTGGTAACAATGATTCGATAGTTCTTTACGGAAAACTA
TTAGGAAGCAGTTTTCTGTTTACTGGTGATTTGGAAAAAGAAGGAGAGGAGGAACTGATGGTCAGCTATCCTAATTTAAA
GGCCAGTGTCCTCAAAGCCGGACACCACGGTTCAAAAGGGTCATCGTCTGAAGCTTTTTTGGACCAGCTGCATCCCTCCC
TTGCACTTGTTTCAGCCGGTGAGAACAATCGTTATAAACATCCAAATGATGAAACTTTGAAGCGTTTTAAGAAACGTCAC
ATTAAGGTTTTACGAACAGACCAGAACGGCGCTATCCGTTTTAAGGGGTGGTTTAAGTGGTCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-169)

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-696)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	48.391	100	0.484
comEC/celB	Streptococcus mitis SK321	48.193	100	0.483
comEC/celB	Streptococcus pneumoniae R6	47.39	100	0.475
comEC/celB	Streptococcus pneumoniae D39	47.39	100	0.475
comEC/celB	Streptococcus pneumoniae Rx1	47.39	100	0.475
comEC/celB	Streptococcus pneumoniae TIGR4	47.122	100	0.472
comEC	Lactococcus lactis subsp. cremoris KW2	43.108	99.196	0.428